HLA – PANEL REACTIVE IgG ANTIBODIES PRA SCREEN Test
Test Name: HLA – PANEL REACTIVE IgG ANTIBODIES PRA SCREEN Test
Components: Class I, Class II
Price: 1360.0 AED
Sample Condition: 3 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. Collect specimen preferably 48 hours after dialysis. Provide brief clinical history.
Report Delivery: 10-12 days
Method: Luminex X-Map technology
Test type: Transplantation
Doctor: Nephrologist, Gastroenterologist, Hematologist
Test Department:
Pre Test Information: Collect specimen preferably 48 hours after dialysis. Provide brief clinical history.
Test Details:
The HLA – Panel Reactive IgG Antibodies (PRA) screen test is a laboratory test that is used to determine the presence of antibodies in a person’s blood against human leukocyte antigens (HLA). HLA antigens are proteins found on the surface of cells that play a crucial role in immune responses.
The PRA screen test is typically performed before organ transplantation, such as kidney or heart transplant, to assess the compatibility between the donor and recipient. It helps identify the presence of pre-formed antibodies in the recipient’s blood that could potentially cause rejection of the transplanted organ.
During the test, the recipient’s blood sample is mixed with a panel of cells that express different HLA antigens. If the recipient has antibodies against any of these HLA antigens, the antibodies will bind to the corresponding cells in the panel. The binding is then detected using various techniques, such as flow cytometry or enzyme-linked immunosorbent assay (ELISA).
The results of the PRA screen test are reported as a percentage, known as the panel reactive antibody (PRA) level. A higher PRA level indicates a greater likelihood of antibody-mediated rejection and may pose challenges in finding a suitable organ donor.
The PRA screen test is an important tool in the evaluation of transplant candidates and helps guide the selection of compatible donors. It provides valuable information to transplant teams to minimize the risk of rejection and improve the success of organ transplantation.
Test Name | HLA – PANEL REACTIVE IgG ANTIBODIES PRA SCREEN Test |
---|---|
Components | *Class I*Class II |
Price | 1360.0 AED |
Sample Condition | 3 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. Collect specimen preferably 48 hours after dialysis. Provide brief clinical history. |
Report Delivery | 10-12 days |
Method | Luminex X-Map technology |
Test type | Transplantation |
Doctor | Nephrologist, Gastroenterologist, Hematologist |
Test Department: | |
Pre Test Information | Collect specimen preferably 48 hours after dialysis. Provide brief clinical history. |
Test Details |
The HLA – Panel Reactive IgG Antibodies (PRA) screen test is a laboratory test that is used to determine the presence of antibodies in a person’s blood against human leukocyte antigens (HLA). HLA antigens are proteins found on the surface of cells that play a crucial role in immune responses. The PRA screen test is typically performed before organ transplantation, such as kidney or heart transplant, to assess the compatibility between the donor and recipient. It helps identify the presence of pre-formed antibodies in the recipient’s blood that could potentially cause rejection of the transplanted organ. During the test, the recipient’s blood sample is mixed with a panel of cells that express different HLA antigens. If the recipient has antibodies against any of these HLA antigens, the antibodies will bind to the corresponding cells in the panel. The binding is then detected using various techniques, such as flow cytometry or enzyme-linked immunosorbent assay (ELISA). The results of the PRA screen test are reported as a percentage, known as the panel reactive antibody (PRA) level. A higher PRA level indicates a greater likelihood of antibody-mediated rejection and may pose challenges in finding a suitable organ donor. The PRA screen test is an important tool in the evaluation of transplant candidates and helps guide the selection of compatible donors. It provides valuable information to transplant teams to minimize the risk of rejection and improve the success of organ transplantation. |