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HLA – Narcolepsy DRB115 DQB10602 DQA1*0102 Test

Original price was: 1,610 د.إ.Current price is: 1,450 د.إ.

-10%

The HLA – Narcolepsy DRB1*15 DQB1*0602 DQA1*0102 Test is a specialized diagnostic assessment aimed at identifying specific human leukocyte antigen (HLA) markers that are strongly associated with narcolepsy, a chronic sleep disorder characterized by overwhelming daytime drowsiness and sudden sleep attacks. This test focuses on detecting the presence of the HLA-DRB1*15, HLA-DQB1*0602, and HLA-DQA1*0102 alleles, which have been linked to an increased susceptibility to narcolepsy, particularly Type 1 narcolepsy that involves cataplexy (a sudden, temporary loss of muscle tone triggered by strong emotions).

Conducted at DNA Labs UAE, a leading facility in genetic and molecular diagnostics, this test provides critical insights into an individual’s genetic predisposition to narcolepsy, facilitating early detection and the potential for targeted management strategies. The cost of the test is 1450 AED, reflecting the sophisticated technology and expertise required to accurately identify these specific genetic markers. By undergoing this test, individuals who exhibit symptoms of narcolepsy or have a family history of the disorder can gain a clearer understanding of their condition, enabling them to seek appropriate treatment and lifestyle adjustments to manage their symptoms effectively.

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HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test

At DNA Labs UAE, we offer the HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test for individuals who suspect they may have narcolepsy. This genetic test looks for specific human leukocyte antigen (HLA) markers associated with narcolepsy.

Test Details

The HLA – NARCOLEPSY (DRB1*15 DQB1*06:02 DQA1*01:02) test is a sequencing-based typing (SBT) method that analyzes a person’s genetic material, usually through a blood or saliva sample. The test specifically looks for the presence of the HLA-DQB1*06:02 allele, which is strongly associated with narcolepsy. The test also examines the HLA-DRB1*15 and HLA-DQA1*01:02 alleles, which are additional genetic markers associated with an increased risk of narcolepsy.

Test Components and Price

The test costs AED 1450.0 and requires either a 4 mL (3 mL min.) whole blood sample in 1 Lavender Top (EDTA) tube or a 6 mL (3 mL min.) whole blood sample in 1 Yellow Top (ACD) tube. The sample should be shipped refrigerated and should not be frozen.

Symptoms and Diagnosis

Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, sudden loss of muscle tone (cataplexy), hallucinations, and disrupted nighttime sleep. If you are experiencing these symptoms, it is recommended to consult with a physician or neurologist for further evaluation.

Pre Test Information

No special preparation is required before taking the HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test.

Report Delivery

The test results will be delivered within 10-12 days after the sample is received.

Test Type and Usage

The HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test is a disease association test primarily used in clinical settings to aid in the diagnosis of narcolepsy. It can also be used for research purposes to study the genetic basis of narcolepsy and its potential associations with other conditions or factors.

It’s important to note that a positive result indicates an increased risk of developing narcolepsy, but it does not guarantee that the individual will develop the disorder. Similarly, a negative result does not completely rule out the possibility of developing narcolepsy, as other genetic and environmental factors may also contribute to its development.

If you suspect you may have narcolepsy or are interested in studying the genetic basis of narcolepsy, consider taking the HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test at DNA Labs UAE. Our experienced team of professionals will provide you with accurate and reliable results.

Test Name HLA – NARCOLEPSY DRB1*15 DQB1*0602 DQA1*0102 Test
Components
Price 1450.0 AED
Sample Condition 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE.
Report Delivery 10-12 days
Method Sequencing Based Typing (SBT)
Test type Disease Association
Doctor Physician, Neurologist
Test Department:
Pre Test Information No special preparation required
Test Details

The HLA – NARCOLEPSY (DRB1*15 DQB1*06:02 DQA1*01:02) test is a genetic test that looks for specific human leukocyte antigen (HLA) markers associated with narcolepsy. Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, sudden loss of muscle tone (cataplexy), hallucinations, and disrupted nighttime sleep.

The test specifically looks for the presence of the HLA-DQB1*06:02 allele, which is strongly associated with narcolepsy. This allele is found in more than 90% of individuals with narcolepsy with cataplexy. The test also examines the HLA-DRB1*15 and HLA-DQA1*01:02 alleles, which are additional genetic markers associated with an increased risk of narcolepsy.

By analyzing a person’s genetic material, usually through a blood or saliva sample, the test can determine if they have these specific HLA markers. A positive result indicates an increased risk of developing narcolepsy, although it does not guarantee that the individual will develop the disorder. Conversely, a negative result does not completely rule out the possibility of developing narcolepsy, as other genetic and environmental factors may also contribute to its development.

The HLA – NARCOLEPSY (DRB1*15 DQB1*06:02 DQA1*01:02) test is primarily used in clinical settings to aid in the diagnosis of narcolepsy. It can also be used for research purposes to study the genetic basis of narcolepsy and its potential associations with other conditions or factors.

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