HLA – A2 A*02 Test Price 1010 AED
The HLA – A2 A02 test is a specialized genetic test that identifies the presence of the HLA-A2 antigen, a specific type of Human Leukocyte Antigen (HLA) found on the surface of cells. This antigen plays a crucial role in the immune system’s ability to recognize and respond to foreign substances. This article provides detailed information about the HLA – A2 A02 test, its importance, and what to expect when getting tested in the UAE.
What is the HLA – A2 A*02 Test?
The HLA – A2 A*02 test is used to determine whether an individual carries the HLA-A2 antigen. This information is particularly important for various medical applications, including organ transplantation, disease association studies, and immunotherapy. The presence or absence of the HLA-A2 antigen can significantly influence treatment decisions and outcomes in these contexts.
Symptoms Indicating the Need for the HLA – A2 A*02 Test
While the HLA – A2 A*02 test itself is not directly linked to specific symptoms, certain medical conditions and circumstances may warrant testing:
- Organ Transplant Compatibility: Identifying HLA-A2 status is critical in matching organ donors and recipients to minimize the risk of rejection.
- Disease Association: Some diseases, such as certain types of autoimmune disorders and cancers, have been linked to specific HLA types, including HLA-A2.
- Personalized Medicine: In the field of immunotherapy, particularly for cancers like melanoma, HLA-A2 status can influence treatment strategies and eligibility for certain therapies.
Components of the HLA – A2 A*02 Test
The HLA – A2 A*02 test involves several key components to ensure accurate and reliable results:
- Sample Collection: Typically, a blood sample is collected from the patient. In some cases, a cheek swab or saliva sample may also be used.
- DNA Extraction: DNA is extracted from the collected sample to prepare it for analysis.
- PCR Amplification: Polymerase Chain Reaction (PCR) is used to amplify specific regions of the DNA that correspond to the HLA-A2 antigen.
- Detection and Analysis: Specialized techniques, such as sequence-specific oligonucleotide probing or next-generation sequencing, are used to detect the presence of the HLA-A2 antigen.
Pre-Test Information
No special preparation required
Test Details
HLA-A2 (A*02) is a specific human leukocyte antigen (HLA) allele. HLA genes encode proteins that are involved in the immune system’s recognition and response to foreign substances, such as bacteria or viruses. These proteins are found on the surface of cells and help the immune system distinguish between “self” and “non-self” molecules. The HLA-A2 allele is one of the most common HLA alleles in the human population, particularly among individuals of European descent. It is associated with certain autoimmune diseases, such as type 1 diabetes and celiac disease, as well as with increased susceptibility to certain infections, such as HIV.
Procedure For HLA – A2 A*02
The procedure for the HLA – A2 A*02 test involves the following steps:
- Sample Collection: A healthcare professional will collect a blood sample, cheek swab, or saliva sample.
- Laboratory Processing: The sample is sent to a specialized laboratory where DNA is extracted and prepared for analysis.
- PCR Amplification: The specific regions of the DNA corresponding to the HLA-A2 antigen are amplified using PCR.
- Detection and Analysis: Advanced techniques are used to detect the presence of the HLA-A2 antigen. The results are then interpreted by a trained professional.
Results Interpretation
- Positive Result: A positive result indicates the presence of the HLA-A2 antigen. This information can be used to guide treatment decisions, organ transplant compatibility, and eligibility for certain therapies.
- Negative Result: A negative result indicates the absence of the HLA-A2 antigen. This information is also valuable in understanding disease risk and making informed medical decisions.
Importance of the HLA – A2 A*02 Test in the UAE
In the UAE, where advanced medical care and organ transplantation are available, the HLA – A2 A*02 test plays a vital role in improving patient outcomes. By providing detailed genetic information, this test helps healthcare providers:
- Enhance Transplant Compatibility: Accurate matching between donors and recipients reduces the risk of organ rejection and improves transplant success rates.
- Guide Treatment Decisions: Understanding HLA-A2 status can inform personalized treatment strategies, particularly in the fields of oncology and immunotherapy.
- Improve Disease Management: Identifying genetic predispositions to certain diseases allows for early intervention and better disease management.
Conclusion
The HLA – A2 A02 test is a crucial tool in the realm of personalized medicine, organ transplantation, and disease management. For residents of the UAE, understanding the significance and details of this test can empower them to make informed health decisions. Whether for transplant compatibility, disease association, or personalized treatment planning, the HLA – A2 A02 test provides valuable insights that can enhance medical care and improve health outcomes. If you are considering this test, consult with your healthcare provider to understand how it fits into your overall medical plan.
Components: 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE.
Price: 1010.0 AED
Report Delivery: 10-12 days
Method: Reverse SSOP – Luminex
Test type: Disease Association
Doctor: Physician, Neurologist, Psychiatrist
Test Department:
Pre Test Information: No special preparation required
| Test Name | HLA – A2 A*02 Test |
|---|---|
| Components | |
| Price | 1010.0 AED |
| Sample Condition | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube. Ship refrigerated. DO NOT FREEZE. |
| Report Delivery | 10-12 days |
| Method | Reverse SSOP – Luminex |
| Test type | Disease Association |
| Doctor | Physician, Neurologist, Psychiatrist |
| Test Department: | |
| Pre Test Information | No special preparation required |
| Test Details | HLA-A2 (A*02) is a specific human leukocyte antigen (HLA) allele. HLA genes encode proteins that are involved in the immune system’s recognition and response to foreign substances, such as bacteria or viruses. These proteins are found on the surface of cells and help the immune system distinguish between “self” and “non-self” molecules.The HLA-A2 allele is one of the most common HLA alleles in the human population, particularly among individuals of European descent. It is associated with certain autoimmune diseases, such as type 1 diabetes and celiac disease, as well as with increased susceptibility to certain infections, such as HIV. HLA typing, including HLA-A2 testing, is performed for various purposes, including: 1. Organ transplantation: Matching the HLA types of the donor and recipient is crucial for successful organ transplantation. HLA-A2 testing helps determine the compatibility between the donor and recipient. 2. Disease associations: Certain HLA alleles, including HLA-A2, are associated with an increased risk of developing certain diseases. HLA testing can help identify individuals who may be at higher risk for these conditions. 3. Forensic identification: HLA typing can be used in forensic investigations to determine the genetic profile of an individual based on their HLA alleles. This can be useful in criminal investigations or in identifying human remains. HLA-A2 testing can be done using various methods, including polymerase chain reaction (PCR) and sequence-specific oligonucleotide probes (SSOP). These techniques allow for the detection and identification of specific HLA alleles, including HLA-A2. It is important to note that HLA testing is typically performed in specialized laboratories and requires trained professionals to interpret the results accurately. The results of HLA testing can have implications for various aspects of an individual’s health, including disease susceptibility and treatment options. Therefore, it is important to consult with a healthcare professional or genetic counselor for a comprehensive understanding of HLA test results and their implications. |
