FISH – TRISOMY 21 DOWN SYNDROME Test
Test Name: FISH – TRISOMY 21 DOWN SYNDROME Test
Components: Chromosome & FISH analysis Requisition Form (Form 17) & Prenatal Genetic Testing Consent Form (Form 18)
Price: 1200.0 AED
Sample Condition: 5 mL (3 mL min.) whole blood/ Cord blood from 2 Green Top (Sodium Heparin) tubes OR 5 mL (3 mL min.) Amniotic fluid in a sterile screw capped container OR 2 g Chorionic villus biopsy in normal saline. Ship at 18-22°C.
Report Delivery: Sample Daily by 4 pm; Report 4 days
Method: FISH
Test type: Genetic Disorders
Doctor: Gynecologist
Test Department: CYTOGENETICS
Pre Test Information: Chromosome & FISH analysis Requisition Form (Form 17) & Prenatal Genetic Testing Consent Form (Form 18) is mandatory.
Test Details:
The FISH (Fluorescence In Situ Hybridization) test is a genetic test used to detect specific chromosomal abnormalities, such as trisomy 21 or Down syndrome. It involves using fluorescent probes that bind to specific regions of chromosomes, allowing the identification of extra copies or missing portions of genetic material.
In the case of trisomy 21, the FISH test would analyze cells from a person’s blood or other tissue to determine if there are three copies of chromosome 21 instead of the usual two. Down syndrome is caused by an extra copy of chromosome 21, and the FISH test can provide a rapid and accurate diagnosis.
The FISH test is often used as a screening tool to detect chromosomal abnormalities in prenatal testing, as well as in postnatal testing for individuals suspected to have Down syndrome. It can be performed on a small sample of cells, such as amniotic fluid or chorionic villus sampling (CVS) cells, obtained during pregnancy, or on blood cells from an individual after birth.
It is important to note that while the FISH test can provide a quick diagnosis, it only detects trisomy 21 and does not provide information about other potential genetic disorders or abnormalities. Further testing, such as a chromosomal microarray analysis or a full karyotype, may be recommended to provide a more comprehensive evaluation of an individual’s genetic profile.
Test Name | FISH – TRISOMY 21 DOWN SYNDROME Test |
---|---|
Components | |
Price | 1200.0 AED |
Sample Condition | 5 mL (3 mL min.) whole blood\/ Cord blood from 2 Green Top (Sodium Heparin) tubes OR 5 mL (3 mL min.) Amniotic fluid in a sterile screw capped container OR 2 g Chorionic villus biopsy in normal saline. Ship at 18-22?\u00f8C. Duly filled Chromosome & FISH analysisRequisition Form (Form 17) &Prenatal Genetic Testing Consent Form (Form 18) is mandatory. |
Report Delivery | Sample Daily by 4 pm; Report 4 days |
Method | FISH |
Test type | Genetic Disorders |
Doctor | Gynecologist |
Test Department: | CYTOGENETICS |
Pre Test Information | Duly filled Chromosome & FISH analysisRequisition Form (Form 17) &Prenatal Genetic Testing Consent Form (Form 18) is mandatory. |
Test Details |
The FISH (Fluorescence In Situ Hybridization) test is a genetic test used to detect specific chromosomal abnormalities, such as trisomy 21 or Down syndrome. It involves using fluorescent probes that bind to specific regions of chromosomes, allowing the identification of extra copies or missing portions of genetic material. In the case of trisomy 21, the FISH test would analyze cells from a person’s blood or other tissue to determine if there are three copies of chromosome 21 instead of the usual two. Down syndrome is caused by an extra copy of chromosome 21, and the FISH test can provide a rapid and accurate diagnosis. The FISH test is often used as a screening tool to detect chromosomal abnormalities in prenatal testing, as well as in postnatal testing for individuals suspected to have Down syndrome. It can be performed on a small sample of cells, such as amniotic fluid or chorionic villus sampling (CVS) cells, obtained during pregnancy, or on blood cells from an individual after birth. It is important to note that while the FISH test can provide a quick diagnosis, it only detects trisomy 21 and does not provide information about other potential genetic disorders or abnormalities. Further testing, such as a chromosomal microarray analysis or a full karyotype, may be recommended to provide a more comprehensive evaluation of an individual’s genetic profile. |