FISH – 17p TP53 DELETION Test
At DNA Labs UAE, we offer the FISH – 17p TP53 DELETION Test to detect the deletion of the TP53 gene in cancer cells. This diagnostic test is crucial in the diagnosis and prognosis of various types of cancer.
Test Details
The FISH (Fluorescence In Situ Hybridization) – 17p (TP53) deletion test is a diagnostic test used to detect the deletion of the TP53 gene in cancer cells. TP53 is a tumor suppressor gene that plays a crucial role in preventing the development of cancer. However, in some cases, the TP53 gene can be deleted or mutated, leading to the loss of its tumor suppressor function.
The FISH test involves using fluorescently labeled DNA probes that specifically bind to the TP53 gene region on chromosome 17. If there is a deletion of the TP53 gene, the fluorescent signal will be absent or reduced in the cancer cells. This test can be performed on tissue samples obtained through biopsy or surgical resection.
The FISH – 17p (TP53) deletion test is commonly used in the diagnosis and prognosis of various types of cancer, including but not limited to, chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), and certain solid tumors. The presence of TP53 deletion or mutation is associated with a poorer prognosis and resistance to certain cancer treatments.
Test Cost
The cost of the FISH – 17p TP53 DELETION Test at DNA Labs UAE is AED 1080.0.
Symptoms and Diagnosis
If you are experiencing symptoms such as unexplained weight loss, fatigue, or abnormal bleeding, it is important to consult with an oncologist. The FISH – 17p TP53 DELETION Test can help in the diagnosis of various types of cancer, including chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), and certain solid tumors.
Referring Details
- Test Name: FISH – 17p TP53 DELETION Test
- Components: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
- Price: 1080.0 AED
- Sample Condition: 5 mL (3 mL min.) whole blood OR 4 mL (2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22°C. DO NOT FREEZE.
- Report Delivery: Sample Daily by 4 pm; Report 4 days
- Method: FISH
- Test Type: Multiple Myeloma
- Doctor: Oncologist
- Test Department: CYTOGENETICS
- Pre Test Information: Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory.
Importance for Oncologists
The results of the FISH – 17p TP53 DELETION Test can help guide treatment decisions and determine the appropriate therapy for patients with TP53 abnormalities. It provides valuable information for oncologists in designing personalized treatment plans and predicting the patient’s response to specific therapies.
For more information or to schedule a test, please contact DNA Labs UAE.
Test Name | FISH – 17p TP53 DELETION Test |
---|---|
Components | |
Price | 1080.0 AED |
Sample Condition | 5 mL (3 mL min.) whole blood OR 4 mL ( 2 mL min.) Bone Marrow from 2 Green Top (Sodium Heparin) tubes. Ship at 18-22?\u00f8C. DO NOT FREEZE. Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Report Delivery | Sample Daily by 4 pm; Report 4 days |
Method | FISH |
Test type | Multiple Myeloma |
Doctor | Oncologist |
Test Department: | CYTOGENETICS |
Pre Test Information | Duly filled Chromosome & FISH analysis Requisition Form (Form 17) is mandatory. |
Test Details | The FISH (Fluorescence In Situ Hybridization) – 17p (TP53) deletion test is a diagnostic test used to detect the deletion of the TP53 gene in cancer cells. TP53 is a tumor suppressor gene that plays a crucial role in preventing the development of cancer. However, in some cases, the TP53 gene can be deleted or mutated, leading to the loss of its tumor suppressor function. The FISH test involves using fluorescently labeled DNA probes that specifically bind to the TP53 gene region on chromosome 17. If there is a deletion of the TP53 gene, the fluorescent signal will be absent or reduced in the cancer cells. This test can be performed on tissue samples obtained through biopsy or surgical resection. The FISH – 17p (TP53) deletion test is commonly used in the diagnosis and prognosis of various types of cancer, including but not limited to, chronic lymphocytic leukemia (CLL), acute myeloid leukemia (AML), and certain solid tumors. The presence of TP53 deletion or mutation is associated with a poorer prognosis and resistance to certain cancer treatments. The results of the FISH – 17p (TP53) deletion test can help guide treatment decisions and determine the appropriate therapy for patients with TP53 abnormalities. It provides valuable information for oncologists in designing personalized treatment plans and predicting the patient’s response to specific therapies. |