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BCR-ABL Gene Rearrangement PCR Qualitative Test

1,000 د.إ

-17%

The BCR-ABL Gene Rearrangement PCR Qualitative Test is a sophisticated diagnostic procedure designed to detect the presence of the BCR-ABL gene fusion, a significant genetic abnormality often associated with certain types of leukemia, including chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). This rearrangement results from a translocation between chromosomes 9 and 22, creating the Philadelphia chromosome, which is a hallmark of these leukemias. The test employs Polymerase Chain Reaction (PCR) technology, a sensitive and specific method that amplifies traces of the BCR-ABL gene sequence, enabling the detection of this genetic anomaly even at very low levels.

Conducted at DNA Labs UAE, a facility renowned for its state-of-the-art genetic testing services, the BCR-ABL Gene Rearrangement PCR Qualitative Test is crucial for the diagnosis, prognosis, and monitoring of treatment response in patients suspected of having leukemia linked to the BCR-ABL fusion gene. This test is instrumental in guiding treatment decisions, including the use of tyrosine kinase inhibitors that specifically target cells harboring this genetic abnormality.

The cost of the BCR-ABL Gene Rearrangement PCR Qualitative Test at DNA Labs UAE is set at 1000 AED. This investment is pivotal for patients requiring a definitive diagnosis of leukemia types associated with the BCR-ABL gene rearrangement, offering them a pathway to targeted treatment and potentially improved outcomes.

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BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test

Cost: AED 1000.0

Test Components

  • Price: 1000.0 AED
  • Sample Condition: 5 mL (3 mL min.) whole blood / Bone marrow in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.

Report Delivery

Sample: Mon / Wed / Fri by 9 am

Report: Tue / Thu / Sat

Method

Real Time PCR

Test Type

Leukemia

Doctor

Oncologist, Hematologist

Test Department

MOLECULAR DIAGNOSTICS

Pre Test Information

No special preparation required

Test Details

The BCR-ABL gene rearrangement PCR qualitative test is a diagnostic tool used to detect the presence of a specific genetic abnormality called the BCR-ABL gene rearrangement. This abnormality is commonly found in patients with chronic myeloid leukemia (CML) and a small percentage of patients with acute lymphoblastic leukemia (ALL).

The test involves extracting DNA from a patient’s blood or bone marrow sample and amplifying specific regions of the BCR and ABL genes using the polymerase chain reaction (PCR) technique. The PCR amplification allows for the detection of any rearrangements or mutations in the BCR-ABL gene.

A positive result indicates the presence of the BCR-ABL gene rearrangement, confirming the diagnosis of CML or ALL. This information is crucial for determining appropriate treatment options and monitoring the response to therapy.

It is important to note that this test is qualitative, meaning it only provides a yes or no answer regarding the presence of the BCR-ABL gene rearrangement. It does not provide information about the quantity or level of the abnormal gene. For quantitative assessment, a separate test called the BCR-ABL quantitative PCR test is performed.

Test Name BCR-ABL GENE REARRANGEMENT PCR QUALITATIVE Test
Components
Price 1000.0 AED
Sample Condition 5 mL (3 mL min.) whole blood \/ Bone marrow in 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.
Report Delivery SampleMon / Wed / Fri by 9 am; Report Tue / Thu / Sat
Method Real Time PCR
Test type Leukemia
Doctor Oncologist, Hematologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information No special preparation required
Test Details

The BCR-ABL gene rearrangement PCR qualitative test is a diagnostic tool used to detect the presence of a specific genetic abnormality called the BCR-ABL gene rearrangement. This abnormality is commonly found in patients with chronic myeloid leukemia (CML) and a small percentage of patients with acute lymphoblastic leukemia (ALL).

The test involves extracting DNA from a patient’s blood or bone marrow sample and amplifying specific regions of the BCR and ABL genes using the polymerase chain reaction (PCR) technique. The PCR amplification allows for the detection of any rearrangements or mutations in the BCR-ABL gene.

A positive result indicates the presence of the BCR-ABL gene rearrangement, confirming the diagnosis of CML or ALL. This information is crucial for determining appropriate treatment options and monitoring the response to therapy.

It is important to note that this test is qualitative, meaning it only provides a yes or no answer regarding the presence of the BCR-ABL gene rearrangement. It does not provide information about the quantity or level of the abnormal gene. For quantitative assessment, a separate test called the BCR-ABL quantitative PCR test is performed.