BCL2 Test Cost AED:1050.0 | Symptoms, Diagnosis, and Details
If you’re looking for information about the BCL2 test, you’ve come to the right place. At DNA Labs UAE, we offer the BCL2 test at a cost of AED 1050.0. Read on to learn more about the test, its components, symptoms, diagnosis, and more.
Test Name: BCL2 Test
Components: Sodium Heparin Vacutainer (2ml)
Price: 1050.0 AED
Sample Condition: Bone Marrow / Peripheral blood
Report Delivery: 3-4 days
Method: FISH
Test Type: Genetics
Doctor: Oncology
Test Department: Pre Test Information
BCL2 can be done with a doctor’s prescription. However, please note that the prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Details
The BCL2 test focuses on a gene that encodes a protein called B-cell lymphoma 2 (Bcl-2). This protein plays a crucial role in regulating programmed cell death, also known as apoptosis. The Bcl-2 protein is part of the Bcl-2 family, which includes both pro-apoptotic and anti-apoptotic members.
The BCL2 gene was initially identified in the context of B-cell lymphoma, a type of cancer that affects the lymphatic system. In certain cases of B-cell lymphoma, there is an overexpression of the Bcl-2 protein, which leads to increased cell survival and resistance to apoptosis. This allows the cancer cells to evade cell death and continue to multiply.
Bcl-2 inhibits the release of cytochrome c from the mitochondria, which is a crucial step in initiating apoptosis. It also interacts with other members of the Bcl-2 family to regulate apoptosis. Maintaining a balance between pro-apoptotic and anti-apoptotic members of the Bcl-2 family is vital for normal cell survival and tissue homeostasis.
Alterations in the BCL2 gene or dysregulation of Bcl-2 protein expression have been associated with various other cancers, including breast cancer, lung cancer, and prostate cancer. Additionally, Bcl-2 has been found to play a role in other biological processes, such as cell differentiation, autophagy, and neuronal development.
The significance of Bcl-2 in cancer biology has led to the development of targeted therapies that specifically inhibit the Bcl-2 protein. These therapies aim to restore apoptosis in cancer cells and promote their death. One example of such a therapy is venetoclax, which has shown promising results in the treatment of certain types of leukemia and lymphoma.
In summary, the BCL2 test focuses on a gene that encodes the Bcl-2 protein, which plays a crucial role in regulating apoptosis. Dysregulation of Bcl-2 expression has been implicated in various cancers, and targeted therapies are being developed to inhibit the Bcl-2 protein and promote cancer cell death.
Test Name | BCL2 Test |
---|---|
Components | Sodium Heparin Vacutainer (2ml) |
Price | 1050.0 AED |
Sample Condition | Bone Marrow \/ Peripheral blood |
Report Delivery | 3-4 days |
Method | FISH |
Test type | Genetics |
Doctor | Oncology |
Test Department: | |
Pre Test Information | BCL2 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
BCL2 is a gene that encodes a protein known as B-cell lymphoma 2 (Bcl-2). This protein plays a crucial role in regulating programmed cell death, or apoptosis. Bcl-2 is a member of the Bcl-2 family of proteins, which includes both pro-apoptotic and anti-apoptotic members. The BCL2 gene was first identified in the context of B-cell lymphoma, a type of cancer that affects the lymphatic system. In certain cases of B-cell lymphoma, there is an overexpression of the Bcl-2 protein, leading to increased cell survival and resistance to apoptosis. This allows the cancer cells to evade cell death and continue to proliferate. Bcl-2 acts by inhibiting the release of cytochrome c from the mitochondria, which is a key step in initiating apoptosis. It also interacts with other members of the Bcl-2 family to regulate apoptosis. The balance between pro-apoptotic and anti-apoptotic members of the Bcl-2 family is crucial for maintaining normal cell survival and tissue homeostasis. Alterations in the BCL2 gene or dysregulation of Bcl-2 protein expression have been implicated in various other cancers, including breast cancer, lung cancer, and prostate cancer. In addition, Bcl-2 has also been found to play a role in other biological processes, such as cell differentiation, autophagy, and neuronal development. The importance of Bcl-2 in cancer biology has led to the development of targeted therapies that specifically inhibit the Bcl-2 protein. These therapies aim to restore apoptosis in cancer cells and promote their death. One example of such a therapy is venetoclax, which has shown promising results in the treatment of certain types of leukemia and lymphoma. In summary, BCL2 is a gene that encodes the Bcl-2 protein, which plays a crucial role in regulating apoptosis. Dysregulation of Bcl-2 expression has been implicated in various cancers, and targeted therapies are being developed to inhibit the Bcl-2 protein and promote cancer cell death. |