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Anti – ds DNA Antibody Crithidia IFA in Dilutions Test

770 د.إ

-10%

The “Anti-ds DNA Antibody Crithidia Indirect Fluorescent Antibody (IFA) in Dilutions Test” is a diagnostic laboratory examination performed to detect the presence of autoantibodies against double-stranded DNA (dsDNA) in the blood. This test is particularly significant in the diagnosis and monitoring of systemic lupus erythematosus (SLE), an autoimmune disease where the immune system mistakenly attacks healthy tissue. The Crithidia luciliae organism, used in this assay, provides a highly specific substrate due to its kinetoplast containing a large amount of double-stranded DNA. When a patient’s serum containing anti-dsDNA antibodies is applied to the Crithidia substrate, it binds to the kinetoplast. This binding is then visualized using a fluorescent-tagged anti-human antibody, providing a clear indication of the presence of these autoantibodies.

The test cost at DNA Labs UAE is 770 AED. DNA Labs UAE is a reputable laboratory that offers a wide range of diagnostic tests, including the Anti-ds DNA Antibody Crithidia IFA in Dilutions Test. They utilize state-of-the-art technology and methodologies to ensure accurate and reliable results, which are crucial for the effective management and treatment of conditions like SLE. The test is conducted by experienced professionals who specialize in autoimmune diagnostics, ensuring that patients receive the highest standard of care.

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ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test

At DNA Labs UAE, we offer the ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test for the detection of antibodies against double-stranded DNA (ds DNA) in a person’s blood. This test is performed using a technique called indirect immunofluorescence assay (IFA) and utilizes Crithidia luciliae, a type of parasite, as a substrate.

Test Details

The ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test is performed using a patient’s blood sample. The sample is mixed with Crithidia luciliae, and if the patient has antibodies against ds DNA, these antibodies will bind to the Crithidia luciliae. A fluorescent dye is then added, which attaches to the bound antibodies, causing them to emit fluorescence under a microscope. The presence and pattern of fluorescence indicate the presence of anti-ds DNA antibodies.

This test is usually performed in dilutions, starting with a high concentration of Crithidia luciliae and then serially diluted to lower concentrations. This allows for the determination of the antibody titer, which is the highest dilution at which the antibodies can still be detected.

Test Cost and Sample Condition

The cost of the ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test is AED 770.0. The sample condition required is 3 mL (1.5 mL min.) serum from 1 SST. The sample should be shipped refrigerated or frozen, and overnight fasting is preferred.

Report Delivery

The sample for the ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test should be provided by 11 am, and the report will be delivered the next day.

Test Type and Doctor

The ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test is a type of autoimmune disorders test. It is typically requested by rheumatologists, dermatologists, and physicians.

Test Department

The ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test is conducted in the Immunopathology department at DNA Labs UAE.

Pre Test Information

Overnight fasting is preferred before taking the ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test.

Diagnosis and Monitoring of Systemic Lupus Erythematosus (SLE)

The ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test is primarily used in the diagnosis and monitoring of systemic lupus erythematosus (SLE), an autoimmune disease. Anti-ds DNA antibodies are highly specific for SLE and are found in approximately 60-70% of patients with the disease. Higher antibody titers are associated with more active disease and can help guide treatment decisions.

It is important to note that this test is not used as a standalone diagnostic tool for SLE, as the presence of anti-ds DNA antibodies can also be seen in other autoimmune diseases and even some infectious diseases. Therefore, it is usually combined with other clinical and laboratory findings to make a definitive diagnosis.

Test Name ANTI – ds DNA ANTIBODY CRITHIDIA IFA IN DILUTIONS Test
Components
Price 770.0 AED
Sample Condition 3 mL (1.5 mL min.) serum from 1 SST. Ship refrigerated or frozen. Overnight fasting is preferred.
Report Delivery Sample Daily by 11 am; Report Next day
Method Immunofluorescence Assay
Test type Autoimmune disorders
Doctor Rheumatologist, Dermatologist, Physician
Test Department: IMMUNOPATHOLOGY
Pre Test Information Overnight fasting is preferred.
Test Details

The anti-ds DNA antibody Crithidia IFA in dilutions test is a laboratory test used to detect the presence of antibodies against double-stranded DNA (ds DNA) in a person’s blood. This test utilizes a technique called indirect immunofluorescence assay (IFA) and uses Crithidia luciliae, a type of parasite, as a substrate.

In this test, the patient’s blood sample is mixed with Crithidia luciliae, and if the patient has antibodies against ds DNA, these antibodies will bind to the Crithidia luciliae. Then, a fluorescent dye is added, which will attach to the bound antibodies, causing them to emit fluorescence under a microscope. The presence and pattern of fluorescence indicate the presence of anti-ds DNA antibodies.

The test is usually performed in dilutions, meaning that the blood sample is initially mixed with a high concentration of Crithidia luciliae, and then serially diluted to lower concentrations. This allows for the determination of the antibody titer, which is the highest dilution at which the antibodies can still be detected.

The anti-ds DNA antibody Crithidia IFA in dilutions test is primarily used in the diagnosis and monitoring of systemic lupus erythematosus (SLE), an autoimmune disease. Anti-ds DNA antibodies are highly specific for SLE and are found in approximately 60-70% of patients with the disease. Higher antibody titers are associated with more active disease and can help guide treatment decisions.

It is important to note that this test is not used as a standalone diagnostic tool for SLE, as the presence of anti-ds DNA antibodies can also be seen in other autoimmune diseases and even some infectious diseases. It is usually combined with other clinical and laboratory findings to make a definitive diagnosis.