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Desmoglein DSG 1 and 3 Antibody in Dilution/End Point Titre Test

Original price was: 2,340 د.إ.Current price is: 2,110 د.إ.

-10%

The Desmoglein DSG 1 and 3 Antibody in Dilution/End Point Titre Test is a specialized diagnostic procedure designed to detect and measure the levels of antibodies against Desmoglein 1 and Desmoglein 3 in the blood. Desmogleins are critical components of the skin and mucous membranes, playing a pivotal role in cell adhesion, thus maintaining the integrity and function of the epidermis. Autoantibodies against Desmoglein 1 and 3 are hallmarks of autoimmune blistering diseases such as Pemphigus Vulgaris and Pemphigus Foliaceus, respectively. These conditions can lead to severe skin blisters and erosions, impacting patients’ quality of life.

The test employs an end point titre methodology, which quantifies the highest dilution of serum at which antibodies can still be detected, providing valuable information on the severity and progression of the disease. This information is crucial for guiding treatment decisions and monitoring response to therapy.

Conducted at DNA Labs UAE, a facility known for its state-of-the-art diagnostic services, the test is priced at 2110 AED. The lab ensures accurate and reliable results, utilizing advanced technologies and methodologies under the supervision of highly qualified professionals. Given the critical nature of diagnosing autoimmune blistering diseases accurately and promptly, the Desmoglein DSG 1 and 3 Antibody in Dilution/End Point Titre Test represents a vital tool in the management of affected patients, aiding in the initiation of appropriate treatments to mitigate symptoms and improve outcomes.

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DESMOGLEIN DSG 1 AND 3 ANTIBODY IN DILUTIONEND POINT TITRE Test

Test Name: DESMOGLEIN DSG 1 AND 3 ANTIBODY IN DILUTIONEND POINT TITRE Test

Components: Desmoglein 1 and 3 antibodies

Price: 2110.0 AED

Sample Condition: 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen. Overnight fasting is preferred.

Report Delivery: Sample Tue / Fri by 9 am; Report 3 days

Method: Immunofluorescence assay (IFA)

Test Type: Autoimmune Disorders

Doctor: Dermatologist

Test Department: IMMUNOPATHOLOGY

Pre Test Information: Overnight fasting is preferred.

Test Details:

The Desmoglein (DSG) 1 and 3 antibody in dilution/end point titre test is a laboratory test used to detect the presence of antibodies against Desmoglein 1 and 3 proteins in the blood. Desmogleins are proteins found in the desmosomes, which are structures that hold cells together in tissues such as the skin and mucous membranes.

Antibodies against Desmoglein 1 and 3 are associated with autoimmune diseases, particularly pemphigus vulgaris and pemphigus foliaceus, which are blistering disorders of the skin and mucous membranes.

In the test, the patient’s blood sample is collected and diluted with a series of dilutions. Each dilution is then tested to determine the highest dilution at which the antibodies against Desmoglein 1 and 3 can still be detected. This highest dilution is known as the endpoint titre.

The test results are reported as the endpoint titre, which indicates the level of antibodies against Desmoglein 1 and 3 in the patient’s blood. Higher endpoint titres suggest a stronger immune response against these proteins and may indicate a higher likelihood of autoimmune blistering disorders such as pemphigus vulgaris or pemphigus foliaceus.

The Desmoglein 1 and 3 antibody in dilution/end point titre test is an important diagnostic tool in the evaluation of autoimmune blistering disorders and helps in confirming the diagnosis and guiding treatment decisions.

Test Name DESMOGLEIN DSG 1 AND 3 ANTIBODY IN DILUTIONEND POINT TITRE Test
Components
Price 2110.0 AED
Sample Condition 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen. Overnight fasting is preferred.
Report Delivery Sample Tue / Fri by 9 am; Report3 days
Method Immunofluorescence assay (IFA)
Test type Autoimmune Disorders
Doctor Dermatologist
Test Department: IMMUNOPATHOLOGY
Pre Test Information Overnight fasting is preferred.
Test Details

The Desmoglein (DSG) 1 and 3 antibody in dilution/end point titre test is a laboratory test used to detect the presence of antibodies against Desmoglein 1 and 3 proteins in the blood.

Desmogleins are proteins found in the desmosomes, which are structures that hold cells together in tissues such as the skin and mucous membranes. Antibodies against Desmoglein 1 and 3 are associated with autoimmune diseases, particularly pemphigus vulgaris and pemphigus foliaceus, which are blistering disorders of the skin and mucous membranes.

In the test, the patient’s blood sample is collected and diluted with a series of dilutions. Each dilution is then tested to determine the highest dilution at which the antibodies against Desmoglein 1 and 3 can still be detected. This highest dilution is known as the endpoint titre.

The test results are reported as the endpoint titre, which indicates the level of antibodies against Desmoglein 1 and 3 in the patient’s blood. Higher endpoint titres suggest a stronger immune response against these proteins and may indicate a higher likelihood of autoimmune blistering disorders such as pemphigus vulgaris or pemphigus foliaceus.

The Desmoglein 1 and 3 antibody in dilution/end point titre test is an important diagnostic tool in the evaluation of autoimmune blistering disorders and helps in confirming the diagnosis and guiding treatment decisions.