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BCL2 Test

1,050 د.إ

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The BCL2 test is a specialized diagnostic procedure aimed at detecting the BCL2 gene rearrangements within cells. BCL2, short for B-cell lymphoma 2, is a gene implicated in various forms of cancer, most notably in lymphomas. Its protein product plays a crucial role in regulating cell death (apoptosis), and its overexpression can lead to an increased survival of cancer cells, contributing to the development and progression of the disease.

At DNA Labs UAE, this test is conducted with precision and care, leveraging advanced molecular techniques to provide accurate results. The test is crucial for patients suspected of having lymphomas or other related conditions, as it helps in confirming the diagnosis, guiding treatment decisions, and providing prognostic information. The cost of the BCL2 test at DNA Labs UAE is 1050 AED, reflecting the sophisticated nature of the testing and the invaluable insights it offers into the patient’s health status. By identifying BCL2 gene rearrangements, healthcare providers can tailor treatment strategies more effectively, potentially improving patient outcomes.

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BCL2 Test Cost AED:1050.0 | Symptoms, Diagnosis, and Details

If you’re looking for information about the BCL2 test, you’ve come to the right place. At DNA Labs UAE, we offer the BCL2 test at a cost of AED 1050.0. Read on to learn more about the test, its components, symptoms, diagnosis, and more.

Test Name: BCL2 Test

Components: Sodium Heparin Vacutainer (2ml)

Price: 1050.0 AED

Sample Condition: Bone Marrow / Peripheral blood

Report Delivery: 3-4 days

Method: FISH

Test Type: Genetics

Doctor: Oncology

Test Department: Pre Test Information

BCL2 can be done with a doctor’s prescription. However, please note that the prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

The BCL2 test focuses on a gene that encodes a protein called B-cell lymphoma 2 (Bcl-2). This protein plays a crucial role in regulating programmed cell death, also known as apoptosis. The Bcl-2 protein is part of the Bcl-2 family, which includes both pro-apoptotic and anti-apoptotic members.

The BCL2 gene was initially identified in the context of B-cell lymphoma, a type of cancer that affects the lymphatic system. In certain cases of B-cell lymphoma, there is an overexpression of the Bcl-2 protein, which leads to increased cell survival and resistance to apoptosis. This allows the cancer cells to evade cell death and continue to multiply.

Bcl-2 inhibits the release of cytochrome c from the mitochondria, which is a crucial step in initiating apoptosis. It also interacts with other members of the Bcl-2 family to regulate apoptosis. Maintaining a balance between pro-apoptotic and anti-apoptotic members of the Bcl-2 family is vital for normal cell survival and tissue homeostasis.

Alterations in the BCL2 gene or dysregulation of Bcl-2 protein expression have been associated with various other cancers, including breast cancer, lung cancer, and prostate cancer. Additionally, Bcl-2 has been found to play a role in other biological processes, such as cell differentiation, autophagy, and neuronal development.

The significance of Bcl-2 in cancer biology has led to the development of targeted therapies that specifically inhibit the Bcl-2 protein. These therapies aim to restore apoptosis in cancer cells and promote their death. One example of such a therapy is venetoclax, which has shown promising results in the treatment of certain types of leukemia and lymphoma.

In summary, the BCL2 test focuses on a gene that encodes the Bcl-2 protein, which plays a crucial role in regulating apoptosis. Dysregulation of Bcl-2 expression has been implicated in various cancers, and targeted therapies are being developed to inhibit the Bcl-2 protein and promote cancer cell death.

For more information about the BCL2 test and other genetic tests, please contact DNA Labs UAE. Our expert oncology team is here to assist you.

Test Name BCL2 Test
Components Sodium Heparin Vacutainer (2ml)
Price 1050.0 AED
Sample Condition Bone Marrow \/ Peripheral blood
Report Delivery 3-4 days
Method FISH
Test type Genetics
Doctor Oncology
Test Department:
Pre Test Information BCL2 can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

BCL2 is a gene that encodes a protein known as B-cell lymphoma 2 (Bcl-2). This protein plays a crucial role in regulating programmed cell death, or apoptosis. Bcl-2 is a member of the Bcl-2 family of proteins, which includes both pro-apoptotic and anti-apoptotic members.

The BCL2 gene was first identified in the context of B-cell lymphoma, a type of cancer that affects the lymphatic system. In certain cases of B-cell lymphoma, there is an overexpression of the Bcl-2 protein, leading to increased cell survival and resistance to apoptosis. This allows the cancer cells to evade cell death and continue to proliferate.

Bcl-2 acts by inhibiting the release of cytochrome c from the mitochondria, which is a key step in initiating apoptosis. It also interacts with other members of the Bcl-2 family to regulate apoptosis. The balance between pro-apoptotic and anti-apoptotic members of the Bcl-2 family is crucial for maintaining normal cell survival and tissue homeostasis.

Alterations in the BCL2 gene or dysregulation of Bcl-2 protein expression have been implicated in various other cancers, including breast cancer, lung cancer, and prostate cancer. In addition, Bcl-2 has also been found to play a role in other biological processes, such as cell differentiation, autophagy, and neuronal development.

The importance of Bcl-2 in cancer biology has led to the development of targeted therapies that specifically inhibit the Bcl-2 protein. These therapies aim to restore apoptosis in cancer cells and promote their death. One example of such a therapy is venetoclax, which has shown promising results in the treatment of certain types of leukemia and lymphoma.

In summary, BCL2 is a gene that encodes the Bcl-2 protein, which plays a crucial role in regulating apoptosis. Dysregulation of Bcl-2 expression has been implicated in various cancers, and targeted therapies are being developed to inhibit the Bcl-2 protein and promote cancer cell death.

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