Symptoms and Testing information for SCNN1G Gene Liddle Syndrome Genetic Test

Symptoms and Testing information for SCNN1G Gene Liddle Syndrome Genetic Test

Liddle syndrome is a rare autosomal dominant disorder that affects the body’s electrolyte balance, leading to high blood pressure, low potassium levels, and metabolic alkalosis. This condition is caused by mutations in the SCNN1G gene, among others, which encode the gamma subunit of the epithelial sodium channel (ENaC) in the kidneys. The ENaC plays a crucial role in sodium absorption and potassium excretion. Mutations in the SCNN1G gene lead to increased activity of this channel, resulting in excessive sodium reabsorption and potassium loss. Recognizing the symptoms of Liddle syndrome is vital for early diagnosis and management. DNA Labs UAE offers a comprehensive genetic test for the SCNN1G gene to help identify this condition.

Symptoms of Liddle Syndrome include:

1. Hypertension: High blood pressure is often the first and most noticeable symptom. It can develop early in life, even in childhood or adolescence, and may be resistant to standard antihypertensive treatments.
2. Hypokalemia: Low levels of potassium in the blood can cause muscle weakness, fatigue, and cramping. Severe cases might lead to paralysis.
3. Metabolic Alkalosis: An imbalance in the body’s acid-base balance, leading to increased blood pH.
4. Low Renin and Aldosterone Levels: Despite the high blood pressure and hypokalemia, levels of renin and aldosterone in the blood are abnormally low.
5. No Edema: Unlike other conditions that cause sodium retention, Liddle syndrome does not typically result in edema (swelling due to fluid retention).

The SCNN1G Gene Liddle Syndrome Genetic Test offered by DNA Labs UAE is a targeted examination for mutations in the SCNN1G gene. This test is crucial for individuals showing symptoms of Liddle syndrome or those with a family history of the condition. Early detection through genetic testing can guide effective management strategies, including specific dietary recommendations and tailored pharmacological treatment.

The cost of the SCNN1G Gene Liddle Syndrome Genetic Test at DNA Labs UAE is 4400 AED. This investment in health allows for a precise diagnosis, facilitating the implementation of an appropriate treatment plan that can significantly improve quality of life and reduce the risk of complications associated with unmanaged hypertension and electrolyte imbalances.

For more information and to schedule a test, please visit DNA Labs UAE.

Symptoms of Liddle Syndrome

Liddle syndrome is a rare autosomal dominant disorder that affects the body’s electrolyte balance, leading to high blood pressure, low potassium levels, and metabolic alkalosis. This condition is caused by mutations in the SCNN1G gene, among others, which encode the gamma subunit of the epithelial sodium channel (ENaC) in the kidneys. The ENaC plays a crucial role in sodium absorption and potassium excretion. Mutations in the SCNN1G gene lead to increased activity of this channel, resulting in excessive sodium reabsorption and potassium loss. Recognizing the symptoms of Liddle syndrome is vital for early diagnosis and management. DNA Labs UAE offers a comprehensive genetic test for the SCNN1G gene to help identify this condition.

  • Hypertension: High blood pressure is often the first and most noticeable symptom. It can develop early in life, even in childhood or adolescence, and may be resistant to standard antihypertensive treatments.

  • Hypokalemia: Low levels of potassium in the blood can cause muscle weakness, fatigue, and cramping. Severe cases might lead to paralysis.

  • Metabolic Alkalosis: An imbalance in the body’s acid-base balance, leading to increased blood pH.

  • Low Renin and Aldosterone Levels: Despite the high blood pressure and hypokalemia, levels of renin and aldosterone in the blood are abnormally low.

  • No Edema: Unlike other conditions that cause sodium retention, Liddle syndrome does not typically result in edema (swelling due to fluid retention).

The SCNN1G Gene Liddle Syndrome Genetic Test offered by DNA Labs UAE is a targeted examination for mutations in the SCNN1G gene. This test is crucial for individuals showing symptoms of Liddle syndrome or those with a family history of the condition. Early detection through genetic testing can guide effective management strategies, including specific dietary recommendations and tailored pharmacological treatment.

The cost of the SCNN1G Gene Liddle Syndrome Genetic Test at DNA Labs UAE is 4400 AED. This investment in health allows for a precise diagnosis, facilitating the implementation of an appropriate treatment plan that can significantly improve quality of life and reduce the risk of complications associated with unmanaged hypertension and electrolyte imbalances.

For more information and to schedule a test, please visit DNA Labs UAE.

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