Symptoms and Testing information for KRAS and NRAS Mutation Analysis Panel Test

Symptoms and Testing information for KRAS and NRAS Mutation Analysis Panel Test

In the realm of genetic testing and molecular diagnostics, understanding the nuances of specific mutations and their implications is critical for effective disease management and treatment planning. Among the myriad of genetic mutations that have garnered attention in medical research and clinical practice, mutations in the KRAS and NRAS genes stand out due to their significant role in the development and progression of various cancers. DNA Labs UAE, a leading facility in the field of genetic testing, offers a comprehensive KRAS and NRAS Mutation Analysis Panel Test designed to detect these mutations and provide crucial information for personalized treatment strategies.

Understanding KRAS and NRAS Mutations

Both KRAS and NRAS genes belong to the RAS gene family, which plays a pivotal role in the regulation of cell division, growth, and death. Mutations in these genes can lead to the production of proteins that are always active, promoting uncontrolled cell growth and contributing to the development of cancer. KRAS mutations are particularly prevalent in colorectal cancer, pancreatic cancer, and non-small cell lung cancer, while NRAS mutations are more commonly associated with melanoma, colorectal cancer, and hematologic malignancies.

Symptoms Indicating the Need for KRAS and NRAS Mutation Analysis

Identifying the presence of KRAS or NRAS mutations can be crucial for determining the most effective treatment approach for patients. While the mutations themselves do not cause specific symptoms, the cancers associated with these mutations may present various signs and symptoms, prompting the need for testing. These can include:

  • Unexplained weight loss
  • Persistent fatigue
  • Changes in bowel habits or blood in stool (colorectal cancer)
  • Jaundice or abdominal pain (pancreatic cancer)
  • New or changing skin lesions (melanoma)
  • A persistent cough or breathlessness (lung cancer)

It’s important to note that these symptoms can be associated with a wide range of conditions, not just cancers linked to KRAS or NRAS mutations. Therefore, a comprehensive evaluation by a healthcare professional is necessary to determine the need for further testing.

Benefits of KRAS and NRAS Mutation Analysis Panel Test

The KRAS and NRAS Mutation Analysis Panel Test provided by DNA Labs UAE offers several benefits for patients and healthcare providers. By identifying the specific type of mutation present, this test can help guide treatment decisions, including the use of targeted therapies that are more likely to be effective against cancers with these mutations. Additionally, the test can provide valuable prognostic information, helping to predict the likely course of the disease.

Test Cost

The cost of the KRAS and NRAS Mutation Analysis Panel Test at DNA Labs UAE is 2570 AED. While the cost may seem significant, the potential benefits in terms of personalized treatment planning and improved patient outcomes can be invaluable. It’s also worth noting that insurance coverage for genetic testing varies, so patients should check with their insurance provider to determine if the cost of the test is covered.


With the increasing importance of personalized medicine in cancer treatment, the KRAS and NRAS Mutation Analysis Panel Test represents a critical tool in the arsenal of diagnostic options. By providing detailed information about the presence and type of mutations in the KRAS and NRAS genes, this test can significantly impact treatment decisions and outcomes for patients with certain types of cancer. For more information and to schedule a test, visit DNA Labs UAE.

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