Symptoms and Testing information for ADAM10 Gene Alzheimer disease type 18 susceptibility to Genetic Test

Symptoms and Testing information for ADAM10 Gene Alzheimer disease type 18 susceptibility to Genetic Test

Symptoms of ADAM10 Gene Alzheimer Disease Type 18 Susceptibility to Genetic Test

Alzheimer’s disease is a progressive neurodegenerative disorder that is characterized by memory loss, cognitive decline, and personality changes. Among the genetic factors contributing to the risk of developing Alzheimer’s, the ADAM10 gene plays a crucial role. Mutations in the ADAM10 gene are linked to Alzheimer disease type 18, a form of the condition with a genetic predisposition. Understanding the symptoms and undergoing genetic testing can be pivotal in managing the risks associated with this gene mutation.

Understanding the Role of ADAM10 in Alzheimer’s Disease

The ADAM10 gene encodes a protein that is involved in the processing of amyloid precursor protein (APP). This processing is crucial for the prevention of amyloid-beta peptide accumulation, which is a hallmark of Alzheimer’s disease. Mutations in the ADAM10 gene can disrupt this process, leading to an increased risk of developing Alzheimer’s disease. Early detection through genetic testing for ADAM10 gene mutations can provide individuals and their families with critical information for managing their health.

Key Symptoms Associated with ADAM10 Gene Mutation

Individuals with a susceptibility to Alzheimer disease type 18 due to ADAM10 gene mutation may exhibit a range of symptoms, which typically develop progressively over time. Key symptoms to be aware of include:

  • Memory loss that disrupts daily life
  • Challenges in planning or solving problems
  • Difficulty completing familiar tasks at home, at work, or at leisure
  • Confusion with time or place
  • Trouble understanding visual images and spatial relationships
  • New problems with words in speaking or writing
  • Misplacing things and losing the ability to retrace steps
  • Decreased or poor judgment
  • Withdrawal from work or social activities
  • Changes in mood and personality, including apathy and depression

Genetic Testing for ADAM10 Gene Mutation

Genetic testing for the ADAM10 gene mutation is a powerful tool in identifying individuals at risk of Alzheimer disease type 18. The test involves analyzing DNA to look for mutations in the ADAM10 gene that are associated with an increased risk of developing Alzheimer’s disease. This information can be invaluable for early intervention strategies and for family members to understand their own risk of developing the disease.

Test Cost and Where to Get Tested

The cost of the genetic test for ADAM10 gene Alzheimer disease type 18 susceptibility is 4400 AED. This test can be conducted at specialized genetic laboratories that offer comprehensive genetic testing services. One such facility is DNA Labs UAE, which provides a wide range of genetic testing services, including the ADAM10 gene test. For more information about the test and to schedule an appointment, please visit DNA Labs UAE.


Alzheimer’s disease poses significant challenges not only to those who suffer from it but also to their families. Understanding the genetic factors that contribute to the risk of developing Alzheimer’s, such as mutations in the ADAM10 gene, can provide crucial insights for early detection and management. With the availability of genetic testing, individuals can take proactive steps towards understanding their risk and implementing preventive measures. If you or a loved one is experiencing symptoms associated with Alzheimer’s disease, consider discussing genetic testing options with your healthcare provider.

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