The RNASEH2A gene is associated with Aicardi-Goutieres syndrome type 4 (AGS4), a rare genetic disorder that typically presents in infancy with severe neurological symptoms, including developmental delay, spasticity, and encephalopathy. AGS mimics congenital viral infections and is characterized by an overactive immune response in the brain. The RNASEH2A gene plays a crucial role in DNA repair and the maintenance of genome stability. Mutations in this gene disrupt these processes, leading to the accumulation of DNA fragments in the cell, triggering an abnormal immune response.
A genetic test for the RNASEH2A gene can confirm a diagnosis of Aicardi-Goutieres syndrome type 4. This test is particularly useful for families with a history of the condition or when a child presents with symptoms suggestive of AGS4. The test involves analyzing the patient's DNA, extracted from a blood sample, for mutations in the RNASEH2A gene that are known to cause the disorder.
In the UAE, this specific genetic test is available at DNA Labs UAE, a leading provider of genetic testing and analysis services. The cost of the RNASEH2A gene test for Aicardi-Goutieres syndrome type 4 is 4400 AED. This comprehensive test not only aids in the diagnosis of AGS4 but also helps in the management and treatment planning for affected individuals. It can also provide valuable information for family planning to at-risk couples.
The SAMHD1 gene plays a critical role in the human body's immune response and cell cycle regulation. Mutations in this gene are associated with Aicardi-Goutières syndrome type 5 (AGS5), a rare genetic disorder that affects the brain, immune system, and skin. This condition is characterized by early-onset encephalopathy, which presents with severe intellectual disability, loss of motor control, and seizures, alongside symptoms like skin rashes and an increased susceptibility to autoimmune conditions.
To diagnose AGS5, genetic testing of the SAMHD1 gene is essential. DNA Labs UAE offers a comprehensive genetic test for this purpose, enabling precise identification of mutations in the SAMHD1 gene. The test is crucial for confirming the diagnosis of AGS5, understanding the genetic basis of the condition, and facilitating genetic counseling for affected families.
The cost of the SAMHD1 Gene Aicardi-Goutières syndrome type 5 Genetic Test at DNA Labs UAE is 4400 AED. This investment covers the detailed analysis necessary to detect the specific mutations in the SAMHD1 gene that are responsible for AGS5. Early and accurate diagnosis through this test can significantly impact the management and treatment options for individuals with this syndrome, providing them with a better quality of life.
The ADAR gene Aicardi-Goutieres syndrome type 6 genetic test is a specialized diagnostic tool used to identify mutations in the ADAR gene, which are linked to Aicardi-Goutieres syndrome type 6 (AGS6). AGS6 is a rare genetic disorder characterized by inflammation of the brain, skin lesions, and intellectual disability. Early detection through genetic testing can aid in the management and treatment of the condition.
Performed at DNA Labs UAE, the test involves analyzing the patient's DNA to look for specific mutations in the ADAR gene that are known to cause AGS6. This process helps in confirming the diagnosis, allowing for a better understanding of the disease's progression and the potential impact on the patient's health.
The cost of the ADAR gene Aicardi-Goutieres syndrome type 6 genetic test is 4400 AED. This investment covers the expenses associated with the sophisticated techniques and technologies required to accurately detect mutations in the ADAR gene. By choosing to undergo this test at DNA Labs UAE, patients can expect a reliable diagnosis, which is crucial for planning the appropriate care and treatment strategies for those affected by AGS6.
The IFIH1 gene plays a crucial role in the immune system, acting as a first line of defense against viral infections. Mutations in this gene can lead to Aicardi-Goutieres syndrome type 7, a rare genetic disorder characterized by severe neurological abnormalities and immune system dysfunction. This condition mimics a viral infection even in the absence of an actual virus, leading to significant brain damage and developmental issues.
To diagnose Aicardi-Goutieres syndrome type 7, a genetic test focusing on the IFIH1 gene is essential. DNA Labs UAE offers this specialized genetic testing service. The test is designed to identify mutations in the IFIH1 gene that are responsible for the syndrome, providing crucial information for diagnosis, management, and genetic counseling of affected families.
The cost of the IFIH1 Gene Aicardi-Goutieres syndrome type 7 Genetic Test at DNA Labs UAE is 4400 AED. This test is a valuable resource for families seeking answers to complex neurological and immunological symptoms presenting in their children, guiding them towards appropriate care and support strategies.
The DCPS Gene Al-Raqad Syndrome Genetic Test is a specialized diagnostic tool offered by DNA Labs UAE, designed to detect mutations in the DCPS gene, which are linked to the rare genetic disorder known as Al-Raqad syndrome. Al-Raqad syndrome is characterized by a range of symptoms, including developmental delays, intellectual disability, and skeletal abnormalities. Early detection through genetic testing is crucial for managing the condition and providing appropriate care and interventions.
DNA Labs UAE, a leading provider of genetic testing services, conducts this test with precision and care, ensuring reliable results for patients and their families. The test is priced at 4400 AED, reflecting the comprehensive analysis and detailed report provided. By identifying specific genetic mutations associated with Al-Raqad syndrome, the test enables healthcare professionals to make informed decisions about treatment options and supports families in understanding the condition better.
The GFAP gene Alexander disease genetic test is a specialized diagnostic tool used to identify mutations in the GFAP gene, which are indicative of Alexander disease. Alexander disease is a rare neurological disorder that affects the brain's white matter, leading to a wide range of neurological symptoms and physical disabilities. The GFAP gene encodes the glial fibrillary acidic protein, which is primarily found in astrocytes, a type of glial cell in the brain. Mutations in this gene disrupt the normal function of astrocytes, leading to the accumulation of Rosenthal fibers and the progressive deterioration of white matter.
The test is conducted through a blood sample, where DNA is extracted and analyzed for mutations in the GFAP gene. It is a crucial step for families with a history of Alexander disease or individuals showing symptoms, as early diagnosis can help in managing the disease more effectively, although there is currently no cure.
Conducted by DNA Labs UAE, the test costs 4400 AED. DNA Labs UAE is a reputable facility known for its advanced genetic testing services. They provide detailed analysis and interpretation of the results, ensuring that individuals and their healthcare providers have the necessary information for appropriate medical and supportive care planning.
The SLC16A2 gene test is a critical diagnostic tool for Allan-Herndon-Dudley syndrome (AHDS), a rare X-linked recessive disorder affecting neurological development and function. This genetic test focuses on identifying mutations in the SLC16A2 gene, which plays a significant role in thyroid hormone transport across the brain. Mutations in this gene can lead to the characteristic symptoms of AHDS, including intellectual disability, muscle weakness, and movement disorders.
DNA Labs UAE offers this specialized genetic test for individuals suspected of having AHDS. The test cost is set at 4400 AED. Conducting the test involves collecting a DNA sample, usually through a blood draw, which is then analyzed in the lab for any genetic anomalies in the SLC16A2 gene. The results from this test can provide essential information for the diagnosis, management, and understanding of the condition, allowing for tailored care and support for affected individuals and their families.
The ATRX Gene Alpha-thalassemia/mental retardation syndrome genetic test is a specialized diagnostic tool designed to identify mutations in the ATRX gene, which are linked to a rare condition known as Alpha-thalassemia/mental retardation syndrome (ATR-X). This syndrome is characterized by a combination of alpha-thalassemia, a blood disorder that reduces the production of hemoglobin, and intellectual disability, along with various other physical anomalies. The ATRX gene plays a crucial role in chromatin remodeling, which is essential for normal development, and mutations in this gene can lead to the diverse symptoms observed in affected individuals.
Conducted at DNA Labs UAE, a leading facility in genetic diagnostics, the test offers a comprehensive analysis of the ATRX gene to identify potential mutations. The cost of the test is 4400 AED, reflecting the intricate technology and expertise required to accurately diagnose this complex condition. By opting for this test, individuals at risk or families with a history of the syndrome can gain crucial insights into their genetic makeup, enabling informed decisions regarding management, treatment options, and genetic counseling. DNA Labs UAE ensures confidentiality and provides support through expert genetic counselors to help interpret the results and guide the next steps for affected individuals and their families.
The ATP1A2 gene is associated with Alternating Hemiplegia of Childhood type 1 (AHC1), a rare neurological disorder characterized by recurrent episodes of hemiplegia (paralysis of one side of the body) that can alternate from one side to the other. Symptoms often manifest in infancy or early childhood and can include a wide range of other neurological issues, such as developmental delay, seizures, and abnormalities in movements. The ATP1A2 gene encodes an essential enzyme for maintaining the proper balance of sodium and potassium ions in nerve cells, crucial for normal brain function.
A genetic test for mutations in the ATP1A2 gene can confirm a diagnosis of Alternating Hemiplegia of Childhood type 1. This test is particularly valuable for affected individuals and their families for several reasons. Firstly, it provides a definitive diagnosis, helping to guide treatment and management strategies. Secondly, it offers information on the genetic basis of the condition, which can be useful for understanding the risk of recurrence in future pregnancies.
In the United Arab Emirates, DNA Labs UAE offers a genetic test for the ATP1A2 gene, catering to individuals who might be showing symptoms of AHC1 or have a family history of the disorder. The cost of the test is 4400 AED. The process involves collecting a DNA sample, typically through a blood draw or a cheek swab, which is then analyzed in the laboratory for mutations in the ATP1A2 gene. The results from this test can provide critical insights for families and healthcare providers, enabling informed decisions about care and support for individuals with AHC1.
The ATP1A3 gene is implicated in a rare neurological disorder known as Alternating Hemiplegia of Childhood type 2 (AHC2). This condition is characterized by recurrent episodes of paralysis that affects either side of the body, dystonia, developmental delay, and seizures. The ATP1A3 gene encodes a subunit of the Na+/K+ ATPase pump, crucial for maintaining the electrochemical gradient across the cell membrane, which is essential for normal brain function.
DNA Labs UAE offers a specialized genetic test aimed at identifying mutations in the ATP1A3 gene, which can confirm a diagnosis of AHC2. This test is particularly important for families seeking a definitive diagnosis and for guiding treatment plans. The cost of the test is 4400 AED. Early diagnosis through genetic testing can lead to better management of the symptoms and improve the quality of life for individuals affected by this condition.
