Test Price
1,500 AEDโ Home Collection Available
Metanephrines Fractionated, Random Urine Test | 1500 AED | DHA Licensed Facility
Executive Summary & Core Metrics
- Diagnostic Accuracy: 99.9% sensitivity achieved through ISO 9001:2015 certified HPLC-EC methodology for fractionated metanephrine quantification.
- Turnaround Time: Results delivered within 3โ6 working days from sample receipt at our Dubai Healthcare City laboratory.
- Home Collection Available: Sterile urine collection kit provided with acidification tube and full instructions; courier pickup arranged at your convenience.
- Post-Test Consultation: Complimentary telephone follow-up with a qualified clinician to interpret your results and advise next steps.
- Insurance Verification: Direct coverage check via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This advanced urinary test quantifies fractionated metanephrines (metanephrine and normetanephrine) in a random urine specimen. It serves as a first-line biochemical screen for catecholamine-secreting neuroendocrine tumours, most notably pheochromocytoma. The assay is performed using High-Performance Liquid Chromatography with Electrochemical Detection (HPLC-EC), a gold-standard technique that delivers high-resolution separation and quantification. All processes operate under ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139), ensuring reproducible, clinically actionable results.
| Feature | Our Test (Premium) | Closest Alternative |
|---|---|---|
| Methodology | HPLC with Electrochemical Detection (LC-EC) | Basic HPLC or Immunoassay |
| Precision | Fractionated, high-resolution quantification of metanephrine and normetanephrine | Often total metanephrines only |
| Turnaround Time | 3โ6 working days (ISO-certified) | 5โ10 days (non-accredited) |
| Accreditation | ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Unknown or none |
| Regulatory Compliance | Full DHA/MOHAP, UAE PDPL, Federal Law No. 2 of 2019 | Variable |
Physician Insight & Safety Protocols
โFractionated metanephrine levels provide a critical biochemical clue in the workup for neuroendocrine tumours, but no single laboratory value should be interpreted in isolation. These results must be correlated with the patient's clinical presentation, imaging findings, and blood pressure profile. I strongly recommend discussing every aspect of this report with your treating oncologist or endocrinologist before making any management decisions.โ
โ Mr. Prabhakar Reddy Kalathoor, Specialist Diagnostic Radiology | DHA Registration ID: 61713011
โ Medication Advisory
Do not discontinue any prescribed medication without explicit instructions from your physician. Abrupt cessation of antihypertensives or other chronic therapies can lead to serious adverse events. Certain drugs, including Alpha-Methyldopa, Buspirone, Codeine, L-dopa, Paracetamol, and Metoclopramide, may interfere with metanephrine measurements and must be discussed with your doctor prior to testing.
Exclusion Criteria & Emergency Red Flags
- Strictly avoid Alpha-Methyldopa, Buspirone, Codeine, Isoproterenol metabolite, Mandelamine, L-dopa, Paracetamol, Metoclopramide, pepper, alcoholic beverages, tea/coffee, tobacco, and strenuous exercise for at least 72 hours before and during specimen collection.
- Urine must be acidified with 50% non-concentrated HCl to pH 1โ2 immediately after collection; improper acidification may invalidate results.
- ER Red Flags: Sudden severe headache, heart palpitations, excessive sweating, and dangerously elevated blood pressure may signal a catecholamine crisis โ seek emergency medical attention immediately.
Patient FAQ & Clinical Guidance
1. What does this test measure?
It measures fractionated metanephrine and normetanephrine levels in a random urine sample to screen for catecholamine-secreting neuroendocrine tumours such as pheochromocytoma and paraganglioma.
2. How should I prepare for the test?
Avoid all listed medications, caffeine, alcohol, tobacco, and strenuous exercise for 72 hours prior to collection. Collect a random urine specimen in the provided sterile container and acidify immediately with the supplied HCl solution. Follow the kit instructions carefully to ensure accurate results.
3. What do abnormal results mean?
Elevated fractionated metanephrines may indicate the presence of a catecholamine-secreting tumour. Your specialist will correlate the results with imaging (CT, MRI, or MIBG scan) and clinical findings to determine the appropriate diagnostic and therapeutic pathway.
4. Is home collection safe for this test?
Yes. Our dedicated courier service delivers a sterile collection kit with a pre-measured acidification tube and step-by-step instructions. The sealed specimen is transported under temperature-controlled conditions to our ISO-certified laboratory in Dubai Healthcare City.
UAE Regulatory & Data Privacy Adherence
Your health data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All clinical procedures, including patient consent and safety protocols, comply with Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA) and operates under the oversight of the Ministry of Health and Prevention (MOHAP).
Clinical & Logistical Metadata
| Test Name | Metanephrines Fractionated, Random Urine |
| Price (AED) | 1,500 AED |
| Turnaround Time | 3โ6 working days |
| Sample Type / Matrix | Random Urine (acidified to pH 1โ2 with 50% HCl) |
| Methodology Used | High-Performance Liquid Chromatography with Electrochemical Detection (HPLC-EC) |
| ICD-10-CM Code | E27.5 (Adrenomedullary hyperfunction) |
| LOINC Code | 32218-8 (Metanephrines panel [Moles/volume] in Urine) |
| DHA Facility License & Laboratory Address | DHA Facility License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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