Test Price
650 AED✅ Home Collection Available
Steroid Panel: 21‑Hydroxylase Deficiency Test in UAE | 650 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection – available daily 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in result interpretation by DHA‑licensed physicians.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
Our Steroid Panel quantifies key adrenal steroids using LC‑MS/MS, the gold‑standard method for 21‑hydroxylase deficiency diagnosis. This comprehensive profile measures 17‑hydroxyprogesterone, androstenedione, and cortisol with sub‑nanogram precision, eliminating cross‑reactivity seen in immunoassays.
| Feature | Our Test (LC‑MS/MS) | Alternative (Immunoassay) |
|---|---|---|
| Methodology | LC‑MS/MS – liquid chromatography‑tandem mass spectrometry | Enzyme‑linked immunoassay (ELISA/RIA) |
| Analytical Sensitivity | 0.05–0.1 ng/mL | 1–5 ng/mL |
| Specificity / Cross‑reactivity | Minimal; resolves structurally similar steroids | Significant interference from other adrenal steroids |
| Panel Depth | Multi‑analyte: 17‑OHP, androstenedione, cortisol, etc. | Often only 17‑OHP (limited profiling) |
| Turnaround Time | 3–4 working days (Mon/Thu by 9 AM → Wed/Sat report) | 1–2 days |
| Clinical Utility | Definitive CAH diagnosis, therapy monitoring | Screening only; confirmatory test required |
Physician Insight & Safety Protocols
“I appreciate the anxiety that abnormal adrenal results can bring. The LC‑MS/MS panel offers unmatched specificity, yet I urge all patients to avoid self‑diagnosis and maintain any prescribed corticosteroids unless instructed otherwise by their physician. I, Dr. Ajay Singh, General Practitioner (DHA: 36234132), personally review critical cases to ensure accurate clinical correlation and personalized follow‑up.”
Medication Advisory
Do not discontinue prescribed medication without consulting your doctor. Sudden withdrawal of corticosteroids can lead to adrenal insufficiency.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Acute illness, recent trauma/surgery, ongoing glucocorticoid therapy without adequate washout period, severe hepatic or renal impairment may affect result accuracy.
- Emergency Red Flags: Severe dizziness, fainting, intense abdominal pain, vomiting, dehydration, or signs of adrenal crisis (hypotension, shock) after sample collection – seek immediate medical attention. Do not wait for test results.
Patient FAQ & Clinical Guidance
1. What does the 21‑Hydroxylase Deficiency Test measure and why is it needed?
Our LC‑MS/MS panel accurately measures 17‑hydroxyprogesterone, androstenedione, and cortisol, diagnosing 21‑hydroxylase deficiency with 99.9% sensitivity. This comprehensive steroid profile is essential for confirming congenital adrenal hyperplasia (CAH), evaluating ambiguous genitalia in newborns, and monitoring glucocorticoid replacement therapy under UAE Ministry of Health protocols.
2. Why is LC‑MS/MS methodology superior to traditional immunoassays?
LC‑MS/MS eliminates cross‑reactivity, achieving precise sub‑nanogram steroid quantification essential for accurate congenital adrenal hyperplasia diagnosis. Unlike immunoassays that can falsely elevate 17‑OHP due to cross‑reactive fetal adrenal steroids, mass spectrometry provides unequivocal identification, enabling confident clinical decisions and reducing unnecessary repeat testing.
3. How should I prepare for the 21‑Hydroxylase Deficiency blood test?
Fast 8 hours, draw blood between 8‑10 AM, and disclose corticosteroid use to your doctor. Diurnal variation significantly affects steroid levels, so a morning sample is mandatory. Avoid SST gel‑barrier tubes; only a plain red‑top serum tube is acceptable, and the sample must be refrigerated or frozen immediately after collection. Our VIP home phlebotomy team ensures all pre‑analytical requirements are strictly followed.
4. What is the turnaround time for results?
Reports are issued within 3–4 working days. Samples received Monday or Thursday by 9 AM are processed and reported by Wednesday or Saturday respectively.
UAE Regulatory & Data Privacy Adherence
Your health data is protected under Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree‑Law No. 4 of 2016 on Medical Liability. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and licensed by the Dubai Health Authority under facility number 1143.
Clinical & Logistical Metadata
| Test Name | Steroid Panel: 21‑Hydroxylase Deficiency Test |
| Price (AED) | 650 AED |
| Turnaround Time | 3–4 working days |
| Sample Type / Matrix | Blood (Serum) |
| Methodology Used | LC‑MS/MS (Liquid Chromatography‑Tandem Mass Spectrometry) |
| ICD‑10‑CM Code | E25.0 |
| LOINC Code | 20574-3 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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