Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test
Are you worried about passing on a genetic disorder to your offspring? DNA Labs UAE offers a comprehensive Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test to help you make informed decisions about your reproductive health.
Test Details
The Pre-implantation Genetic Diagnosis (PGD) is a procedure used in assisted reproductive technology (ART) that allows the identification of genetic disorders in embryos before they are implanted into the uterus. This test is typically recommended for couples who have a high risk of passing on a genetic disorder to their children.
Single gene disorders are genetic disorders caused by mutations in a single gene. These disorders can be inherited in an autosomal dominant or recessive manner, or may be X-linked. Some examples of single gene disorders include cystic fibrosis, sickle cell anemia, and Huntington’s disease.
In the case of a known mutation, the PGD test involves testing embryos for the specific mutation that is known to cause the genetic disorder. This is done by analyzing DNA samples from cells removed from the embryo before it is implanted into the uterus. By selecting embryos that do not carry the mutation, the risk of passing on the genetic disorder to the child can be significantly reduced.
Test Components
- EDTA Vacutainer (2ml)
Test Price
The cost of the Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test is AED 9000.0.
Sample Condition
The test requires a peripheral blood sample from both parents and the affected child.
Report Delivery
The test results will be delivered within 15-20 days.
Method
The test is conducted using Sanger Sequencing, a widely used DNA sequencing method.
Test Type
The Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test falls under the Genetics category.
Doctor
This test can be requested by a Gynecologist.
Test Department
This test is available in the Pre Test Information department.
Pre Test Information
Please note that a doctor’s prescription is required to proceed with the Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test. However, the prescription is not applicable for surgery and pregnancy cases or for individuals planning to travel abroad.
At DNA Labs UAE, we understand the importance of genetic testing in reproductive health. Our Pre-implantation Genetic Disorder (PGD) Single Gene Disorder – Known Mutation – Baseline Test provides valuable information to couples who are at risk of passing on genetic disorders to their children. By identifying specific mutations and developing testing protocols, we can help you make informed decisions and increase the chances of having a healthy baby.
| Test Name | Pre-implantation Genetic DisorderPGD Single gene Disorder- Known mutation- Baseline Test |
|---|---|
| Components | EDTA Vacutainer (2ml) |
| Price | 9000.0 AED |
| Sample Condition | Peripheral blood of parents and affected child |
| Report Delivery | 15-20 days |
| Method | Sanger Sequencing |
| Test type | Genetics |
| Doctor | Gynecologist |
| Test Department: | |
| Pre Test Information | Pre-implantation Genetic Disorder/PGD (Single gene Disorder- Known mutation)- Baseline can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details |
Pre-implantation Genetic Diagnosis (PGD) is a procedure used in assisted reproductive technology (ART) that enables the identification of genetic disorders in embryos before they are implanted into the uterus. PGD is typically used in couples who have a high risk of passing on a genetic disorder to their offspring. Single gene disorders are genetic disorders caused by mutations in a single gene. These disorders can be inherited in an autosomal dominant or recessive manner or may be X-linked. Examples of single gene disorders include cystic fibrosis, sickle cell anemia, and Huntington’s disease. In the case of a known mutation, PGD involves testing embryos for the specific mutation that is known to cause the genetic disorder. This is typically done by analyzing DNA samples from cells removed from the embryo before it is implanted into the uterus. Embryos that do not carry the mutation can then be selected for implantation, reducing the risk of the genetic disorder being passed on to the child. The baseline for PGD in cases of single gene disorders with a known mutation involves identifying the specific genetic mutation and developing a testing protocol to detect the mutation in embryos. This may involve using techniques such as polymerase chain reaction (PCR) or fluorescence in situ hybridization (FISH) to analyze DNA samples from the embryos. The goal is to identify embryos that are free of the mutation and have the best chance of developing into a healthy baby. |
