HLA Hypersensitivity to Abacavir B*5701 Test
At DNA Labs UAE, we offer the HLA Hypersensitivity to Abacavir B*5701 Test at a cost of AED 1400.0. This genetic test helps determine if an individual has a specific human leukocyte antigen (HLA) gene variant called HLA-B*57:01.
Test Components and Sample Condition
The test requires a sample of 4 mL (minimum 3 mL) whole blood in 1 Lavender Top (EDTA) tube or 6 mL (minimum 3 mL) whole blood in 1 Yellow Top (ACD) tube. Alternatively, a buccal swab collected in a sterile container can also be used. The sample should be shipped refrigerated and should not be frozen.
Report Delivery and Method
The report for the HLA Hypersensitivity to Abacavir B*5701 Test is typically delivered within 10-12 days. The test is performed using PCR (Polymerase Chain Reaction) sequencing method.
Test Type and Doctor
The HLA Hypersensitivity to Abacavir B*5701 Test falls under the category of AIDS tests. It is recommended to consult a physician for this test.
Pre Test Information
No special preparation is required before taking this test.
Test Details
The HLA Hypersensitivity to Abacavir (B*57:01) Test is crucial in identifying individuals who are at risk of developing a severe hypersensitivity reaction to the antiretroviral drug abacavir, which is commonly used to treat HIV infection. The test helps determine if an individual has the HLA-B*57:01 variant, which is associated with an increased risk of hypersensitivity reaction to abacavir.
Hypersensitivity reactions to abacavir can manifest as fever, rash, gastrointestinal symptoms, respiratory symptoms, and in severe cases, life-threatening conditions such as Stevens-Johnson syndrome or toxic epidermal necrolysis. By identifying individuals with the HLA-B*57:01 variant, healthcare providers can avoid prescribing abacavir to these individuals and opt for alternative antiretroviral medications.
This test plays a crucial role in preventing severe hypersensitivity reactions and improving patient safety and treatment outcomes. It is typically performed using a blood sample, and the results can guide healthcare providers in making informed decisions regarding the use of abacavir in HIV treatment.
Test Name | HLA HYPERSENSITIVITY TO ABACAVIR B*5701 Test |
---|---|
Components | |
Price | 1400.0 AED |
Sample Condition | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube OR Buccal swab collected in a sterile container. Ship refrigerated. DO NOT FREEZE. |
Report Delivery | 10-12 days |
Method | PCR, Sequencing |
Test type | AIDS |
Doctor | Physician |
Test Department: | |
Pre Test Information | No special preparation required |
Test Details |
The HLA hypersensitivity to abacavir (B*57:01) test is a genetic test that determines if an individual has a specific human leukocyte antigen (HLA) gene variant called HLA-B*57:01. This variant is associated with an increased risk of hypersensitivity reaction to the antiretroviral drug abacavir, which is used to treat HIV infection. The test is usually performed before starting abacavir therapy to identify individuals who are at risk of developing a severe hypersensitivity reaction. This reaction can manifest as fever, rash, gastrointestinal symptoms, respiratory symptoms, and potentially life-threatening conditions such as Stevens-Johnson syndrome or toxic epidermal necrolysis. By identifying individuals with the HLA-B*57:01 variant, healthcare providers can avoid prescribing abacavir to these individuals and opt for alternative antiretroviral medications. This test helps prevent severe hypersensitivity reactions and improves patient safety and treatment outcomes. The test is typically performed using a blood sample, and the results can guide healthcare providers in making informed decisions regarding the use of abacavir in HIV treatment. |