FLT3 ITD D835Y Mutation Detection Test
Test Name: FLT3 ITD D835Y Mutation Detection Test
Components: EDTA Vacutainer (2ml)
Price: 1200.0 AED
Sample Condition: Bone marrow / Peripheral blood (Transport immediately)
Report Delivery: 3-4 days
Method: End Point PCR
Test Type: Genetics
Doctor: General Physician
Test Department:
Pre Test Information: FLT3 (ITD, D835Y) Mutation Detection can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Test Details
FLT3 (ITD, D835Y) mutation detection is a molecular diagnostic test used to identify specific mutations in the FLT3 gene. FLT3 is a receptor tyrosine kinase that plays a crucial role in the regulation of cell growth and survival.
Mutations in the FLT3 gene, particularly internal tandem duplications (ITDs) and D835Y point mutations, are commonly found in patients with acute myeloid leukemia (AML). The FLT3 ITD mutation is characterized by the insertion of multiple copies of a portion of the gene, resulting in constitutive activation of the FLT3 receptor and increased cell proliferation. The D835Y mutation, on the other hand, involves a substitution of the amino acid aspartic acid (D) with tyrosine (Y) at position 835, leading to increased activation of the FLT3 receptor.
Detection of FLT3 mutations is important in the diagnosis and prognosis of AML, as patients with FLT3 mutations tend to have a poorer prognosis and may require different treatment strategies.
The FLT3 (ITD, D835Y) mutation detection test typically involves the analysis of DNA samples, usually obtained from bone marrow or blood, using techniques such as polymerase chain reaction (PCR) and DNA sequencing.
Overall, FLT3 (ITD, D835Y) mutation detection is a valuable tool in the management of AML, allowing for personalized treatment approaches and improved patient outcomes.
Test Name | FLT3 ITD D835Y Mutation Detection Test |
---|---|
Components | EDTA Vacutainer (2ml) |
Price | 1200.0 AED |
Sample Condition | Bone marrow \/ Peripheral blood (Transport immediately) |
Report Delivery | 3-4 days |
Method | End Point PCR |
Test type | Genetics |
Doctor | General Physician |
Test Department: | |
Pre Test Information | FLT3 (ITD, D835Y) Mutation Detection can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
FLT3 (ITD, D835Y) mutation detection is a molecular diagnostic test used to identify specific mutations in the FLT3 gene. FLT3 is a receptor tyrosine kinase that plays a crucial role in the regulation of cell growth and survival. Mutations in the FLT3 gene, particularly internal tandem duplications (ITDs) and D835Y point mutations, are commonly found in patients with acute myeloid leukemia (AML). The FLT3 ITD mutation is characterized by the insertion of multiple copies of a portion of the gene, resulting in constitutive activation of the FLT3 receptor and increased cell proliferation. The D835Y mutation, on the other hand, involves a substitution of the amino acid aspartic acid (D) with tyrosine (Y) at position 835, leading to increased activation of the FLT3 receptor. Detection of FLT3 mutations is important in the diagnosis and prognosis of AML, as patients with FLT3 mutations tend to have a poorer prognosis and may require different treatment strategies. The FLT3 (ITD, D835Y) mutation detection test typically involves the analysis of DNA samples, usually obtained from bone marrow or blood, using techniques such as polymerase chain reaction (PCR) and DNA sequencing. Overall, FLT3 (ITD, D835Y) mutation detection is a valuable tool in the management of AML, allowing for personalized treatment approaches and improved patient outcomes. |