VON WILLEBRAND FACTOR RISTOCETIN COFACTOR ACTIVITY vWFRCo Test

Welcome to DNA Labs UAE, your trusted genetic lab for all your testing needs. In this blog post, we will be discussing the VON WILLEBRAND FACTOR RISTOCETIN COFACTOR ACTIVITY (vWFRCo) Test, including its cost, symptoms, diagnosis, and more.

Test Details

The VON WILLEBRAND FACTOR RISTOCETIN COFACTOR ACTIVITY (vWF:RCo) test is a laboratory test that measures the activity of von Willebrand factor (vWF) in the blood. Von Willebrand factor is a protein that plays a crucial role in blood clotting by helping platelets adhere to the blood vessel walls and form a clot.

During the vWF:RCo test, a blood sample is collected and mixed with a substance called ristocetin. Ristocetin causes platelets to aggregate in the presence of vWF. The degree of platelet aggregation is then measured, which reflects the activity of vWF in the blood.

This test is primarily used to diagnose von Willebrand disease, a bleeding disorder characterized by a deficiency or dysfunction of vWF. It helps determine the quantity and quality of vWF in the blood, which can aid in the diagnosis and classification of von Willebrand disease.

The vWF:RCo test is typically performed alongside other tests, such as the von Willebrand factor antigen test and the von Willebrand factor collagen binding test, to provide a comprehensive assessment of vWF function. The results of these tests help guide treatment decisions and monitor the effectiveness of therapy in individuals with von Willebrand disease.

Test Cost

The cost of the VON WILLEBRAND FACTOR RISTOCETIN COFACTOR ACTIVITY vWFRCo Test is AED 2320.0.

Symptoms and Diagnosis

Von Willebrand disease can present with various symptoms, including:

• Excessive bleeding from minor cuts or injuries
• Frequent nosebleeds
• Easy bruising
• Heavy or prolonged menstrual periods

If you experience any of these symptoms, it is important to consult a hematologist for further evaluation. The diagnosis of von Willebrand disease involves a thorough medical history, physical examination, and laboratory tests, including the vWF:RCo test.

Sample Collection and Transport

To perform the vWF:RCo test, a 3 mL whole blood sample is required. The blood should be collected in a Blue Top (Sodium Citrate) tube and mixed thoroughly by inversion. It is important to transport the sample to the lab within 4 hours. If immediate transportation is not possible, the sample can be processed to obtain platelet-poor plasma (PPP) within 1 hour of collection.

To obtain PPP, the collected blood sample should be centrifuged at 3600 rpm for 15 minutes. The supernatant should then be transferred to a clean plastic tube and centrifuged again at 3600 rpm for another 15 minutes. Finally, the supernatant (PPP) should be transferred to a labeled, clean plastic screw-capped vial and immediately frozen. It is important not to thaw the sample once it has been frozen.

Pre-Test Information

For accurate results, overnight fasting is preferred before undergoing the vWF:RCo test. Additionally, a duly filled Coagulation Requisition Form (Form 15) is mandatory for the test.

Report Delivery

If the sample is received by 11 am, the report will be delivered on the same day by 6 pm.

Conclusion

The VON WILLEBRAND FACTOR RISTOCETIN COFACTOR ACTIVITY vWFRCo Test is a valuable diagnostic tool for von Willebrand disease. It measures the activity of von Willebrand factor in the blood and helps in the diagnosis and classification of this bleeding disorder. If you are experiencing symptoms or have concerns about von Willebrand disease, consult a hematologist and consider undergoing the vWF:RCo test.

For more information or to schedule a test, contact DNA Labs UAE today.