VANGL1 Gene Caudal Regression Syndrome Genetic Test
Welcome to DNA Labs UAE, where we offer the VANGL1 Gene Caudal Regression Syndrome Genetic Test. This test is designed to diagnose individuals with caudal regression syndrome (CRS) by identifying mutations in the VANGL1 gene and other associated genes.
Test Components and Price
The VANGL1 Gene Caudal Regression Syndrome Genetic Test is priced at 4400.0 AED. The test requires a blood sample, extracted DNA, or one drop of blood on an FTA card.
Report Delivery
After the sample is collected, the report will be delivered within 3 to 4 weeks.
Method and Test Type
The test utilizes Next-Generation Sequencing (NGS) technology, which allows for the analysis of multiple genes simultaneously. The test falls under the category of dysmorphology.
Doctor and Test Department
The test is conducted under the supervision of a pediatrician in our Genetics department.
Pre Test Information
Prior to the test, it is important to provide the clinical history of the patient who is undergoing the VANGL1 Gene Caudal Regression Syndrome Genetic Test. Additionally, a genetic counseling session will be conducted to draw a pedigree chart of family members affected by CRS.
Test Details
The VANGL1 gene plays a crucial role in planar cell polarity (PCP), a developmental process necessary for the proper formation and organization of tissues and organs during embryonic development. Mutations in the VANGL1 gene can result in caudal regression syndrome (CRS), a rare congenital disorder characterized by abnormal development in the lower spine and other structures in the lower body. The severity of CRS can vary and may affect various organs and systems, including the spine, lower limbs, genitourinary system, and gastrointestinal tract.
NGS genetic testing is employed to analyze multiple genes simultaneously. In the context of caudal regression syndrome, NGS genetic testing is used to identify mutations in the VANGL1 gene and other associated genes. This aids in the diagnosis of individuals with CRS and enables appropriate medical management and genetic counseling.
It is important to note that the VANGL1 gene is just one of several genes associated with caudal regression syndrome. NGS genetic testing can also identify mutations in other genes related to the condition. The interpretation of genetic test results requires the expertise of a geneticist or genetic counselor, who can provide appropriate counseling and guidance based on the specific findings.
| Test Name | VANGL1 Gene Caudal regression syndrome Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Dysmorphology |
| Doctor | Pediatrics |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for VANGL1 Gene Caudal regression syndrome NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with VANGL1 Gene Caudal regression syndrome NGS Genetic DNA Test gene VANGL1 |
| Test Details |
The VANGL1 gene is involved in a developmental process called planar cell polarity (PCP), which is crucial for the proper formation and organization of tissues and organs during embryonic development. Mutations in the VANGL1 gene can lead to a condition called caudal regression syndrome (CRS). Caudal regression syndrome is a rare congenital disorder characterized by the abnormal development of the lower spine and other structures in the lower body. It can range from mild to severe and may affect various organs and systems, including the spine, lower limbs, genitourinary system, and gastrointestinal tract. NGS (Next-Generation Sequencing) genetic testing is a high-throughput method used to analyze multiple genes simultaneously. In the context of caudal regression syndrome, NGS genetic testing can be used to identify mutations in the VANGL1 gene and other genes associated with the condition. This can help in diagnosing individuals with CRS and providing appropriate medical management and genetic counseling. It’s important to note that the VANGL1 gene is just one of many genes that can be associated with caudal regression syndrome, and NGS genetic testing can help identify mutations in other genes as well. Additionally, the interpretation of genetic test results requires the expertise of a geneticist or genetic counselor who can provide appropriate counseling and guidance based on the specific findings. |
