THROMBOPHILIA PROFILE Test
Are you at risk for blood clotting disorders? Find out with the THROMBOPHILIA PROFILE Test at DNA Labs UAE.
Test Components
- Protein C, Functional
- Protein S Antigen, Free
- Antithrombin Activity, Functional
- Factor V Leiden Mutation
- Prothrombin Gene Mutation
- MTHFR Gene Mutation
Test Price
AED 3510.0
Sample Condition
For the THROMBOPHILIA PROFILE Test, a 3mL whole blood sample is required in a Blue Top (Sodium Citrate) tube. Mix the sample thoroughly by inversion and transport it to the lab within 4 hours. If immediate transport is not possible, make Platelet Poor Plasma (PPP) within 1 hour of collection. Centrifuge the sample at 3600rpm for 15 minutes and transfer the supernatant to a clean plastic tube. Centrifuge the supernatant again at 3600rpm for 15 minutes and finally transfer the supernatant (PPP) to a labelled clean plastic screw-capped vial. Freeze the sample immediately and ship it frozen. DO NOT THAW.
In addition, a 5mL (3mL minimum) whole blood sample is required in 2 Lavender Top (EDTA) tubes. Ship the samples refrigerated. DO NOT FREEZE.
It is recommended to have overnight fasting prior to the test. A duly filled Coagulation Requisition Form (Form 15) is mandatory. Patients should discontinue Heparin for 1 day and Oral Anticoagulants for 7 days before sampling, with prior consent from the treating Physician, as these drugs may affect test results.
Report Delivery
Sample collection on Monday or Thursday by 11 am will have the report delivered on Wednesday or Saturday.
Method
The THROMBOPHILIA PROFILE Test is performed using chromogenic, immunoturbidimetry, and PCR methods.
Test Type
The THROMBOPHILIA PROFILE Test falls under the category of Disorders of Coagulation.
Doctor
This test is conducted by a Hematologist.
Test Department
The THROMBOPHILIA PROFILE Test is conducted in the Coagulation department.
Pre Test Information
Prior to the test, overnight fasting is preferred. A duly filled Coagulation Requisition Form (Form 15) is mandatory. Patients should discontinue Heparin for 1 day and Oral Anticoagulants for 7 days before sampling, with prior consent from the treating Physician, as these drugs may affect test results.
Test Details
The THROMBOPHILIA PROFILE Test is a series of blood tests used to assess the risk of blood clotting disorders, specifically thrombophilia. Thrombophilia refers to a condition where there is an increased tendency for blood clot formation, which can lead to conditions such as deep vein thrombosis (DVT) or pulmonary embolism.
The THROMBOPHILIA PROFILE Test includes the following tests:
- Activated Protein C Resistance (APCR): This test detects the Factor V Leiden mutation, the most common inherited cause of thrombophilia.
- Prothrombin Gene Mutation (PTG20210A): This test detects a mutation in the prothrombin gene, another common inherited cause of thrombophilia.
- Antithrombin (AT) III: This test measures the levels of antithrombin, a protein that helps regulate blood clotting.
- Protein C: This test measures the levels of protein C, a protein that helps regulate blood clotting.
- Protein S: This test measures the levels of protein S, a protein that helps regulate blood clotting.
- Lupus Anticoagulant: This test detects the presence of lupus anticoagulant antibodies, which can increase the risk of abnormal blood clotting.
- Anticardiolipin Antibodies (ACA): This test detects the presence of anticardiolipin antibodies, which can increase the risk of abnormal blood clotting.
The results of the THROMBOPHILIA PROFILE Test can help healthcare providers determine the underlying cause of thrombophilia and guide treatment decisions. Treatment may involve lifestyle modifications, such as weight loss and exercise, or medications to prevent blood clot formation.
Test Name | THROMBOPHILIA PROFILE Test |
---|---|
Components | *ProteinC, Functional*Protein S Antigen, Free *AntithrombinActivityFunctional*FactorV LeidenMutation*ProthrombinGeneMutation *MTHFRgenemutation |
Price | 3510.0 AED |
Sample Condition | 3mLwholebloodin1BlueTop (SodiumCitrate)tube.Mixthoroughly byinversion.TransporttoLabwithin4 hours.Ifthisisnotpossible,makePPP within1hourofcollectionasfollows: Centrifugesampleat3600rpmfor15 min.&transfersupernatanttoaclean plastictube.Centrifugethissupernatant again at 3600 rpm for 15 min. & finally transferthesupernatant(PPP)to1 labelled cleanplasticscrewcappedvial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAWAND 5 mL (3 mL min.) wholebloodin2LavenderTop (EDTA)tubes.Shiprefrigerated.DO NOT FREEZE. Overnight fasting is preferred.Duly filled Coagulation Requisition Form (Form 15) is mandatory. Itisrecommendedthatpatient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior tosamplingasthesedrugsmayaffect testresults. Discontinuationshouldbe with prior consent from the treating Physician. |
Report Delivery | SampleMon / Thu by 11 am; Report Wed / Sat |
Method | Chromogenic, Immunoturbidimetry, PCR |
Test type | Disorders of Coagulation |
Doctor | Hematologist |
Test Department: | COAGULATION |
Pre Test Information | Overnight fasting is preferred.Duly filled Coagulation Requisition Form (Form 15) is mandatory. Itisrecommendedthatpatient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior tosamplingasthesedrugsmayaffect testresults. Discontinuationshouldbe with prior consent from the treating Physician. |
Test Details | Thrombophilia profile test is a series of blood tests that are used to assess the risk of blood clotting disorders, specifically thrombophilia. Thrombophilia refers to a condition where there is an increased tendency for blood clot formation, which can lead to conditions such as deep vein thrombosis (DVT) or pulmonary embolism. The thrombophilia profile test typically includes the following tests: 1. Activated Protein C Resistance (APCR): This test is used to detect a mutation called Factor V Leiden, which is the most common inherited cause of thrombophilia. Individuals with this mutation have a reduced ability to break down blood clots, increasing their risk for clot formation. 2. Prothrombin Gene Mutation (PTG20210A): This test detects a mutation in the prothrombin gene, which is another common inherited cause of thrombophilia. Individuals with this mutation have increased levels of prothrombin, a protein involved in blood clotting, leading to an increased risk of clot formation. 3. Antithrombin (AT) III: This test measures the levels of antithrombin, a protein that helps to regulate blood clotting. Low levels of antithrombin can increase the risk of clot formation. 4. Protein C: This test measures the levels of protein C, a protein that helps to regulate blood clotting. Low levels of protein C can increase the risk of clot formation. 5. Protein S: This test measures the levels of protein S, a protein that helps to regulate blood clotting. Low levels of protein S can increase the risk of clot formation. 6. Lupus Anticoagulant: This test detects the presence of lupus anticoagulant antibodies, which can increase the risk of abnormal blood clotting. 7. Anticardiolipin Antibodies (ACA): This test detects the presence of anticardiolipin antibodies, which can increase the risk of abnormal blood clotting. The results of the thrombophilia profile test can help healthcare providers determine the underlying cause of thrombophilia and guide treatment decisions. Treatment may involve lifestyle modifications, such as weight loss and exercise, or medications to prevent blood clot formation. |