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Tacrolimus Genotyping CYP3A5 Test Cost

Original price was: 1,350 د.إ.Current price is: 1,220 د.إ.

-10%

The Tacrolimus Genotyping CYP3A5 Test is a specialized genetic test performed to determine how an individual metabolizes tacrolimus, a critical immunosuppressive medication commonly used in organ transplant patients to prevent rejection. This test specifically analyzes the CYP3A5 gene, which plays a significant role in the enzyme production that metabolizes tacrolimus and other drugs. Understanding a patient’s CYP3A5 genotype can help healthcare providers tailor drug dosages to achieve optimal therapeutic levels, reducing the risk of drug toxicity or treatment failure.

This precise and valuable test is available at DNA Labs UAE, a leading provider of genetic testing services in the United Arab Emirates. The test is priced at 1220 AED, offering patients and healthcare professionals a critical tool in the management of transplant medications and the customization of treatment plans based on genetic makeup. By leveraging such genetic insights, DNA Labs UAE supports more effective and personalized medical care, particularly for those undergoing organ transplantation.

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TACROLIMUS GENOTYPING CYP3A5 Test

Introduction

The Tacrolimus Genotyping (CYP3A5) test is a genetic test offered by DNA Labs UAE. This test determines an individual’s CYP3A5 genotype, which is crucial for the metabolism of tacrolimus, a medication commonly used in organ transplant patients to prevent rejection.

Test Details

The Tacrolimus Genotyping (CYP3A5) test helps determine an individual’s ability to metabolize tacrolimus, which can vary depending on their CYP3A5 genotype. There are two common genotypes: CYP3A5 expressers (CYP3A5*1) and non-expressers (CYP3A5*3).

CYP3A5 expressers have higher enzyme activity and may require higher doses of tacrolimus for therapeutic levels, while non-expressers have lower enzyme activity and may require lower doses. By identifying an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects.

This test is particularly useful in organ transplant patients who require long-term tacrolimus therapy to ensure proper drug dosing and efficacy.

Test Components and Price

The TACROLIMUS GENOTYPING CYP3A5 Test is priced at 1220.0 AED. The sample condition required is 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. It should be shipped refrigerated and should not be frozen. The report delivery is on Sample Mon / Thu by 11 am and the report will be delivered on Wed / Sat.

Method and Test Type

The Tacrolimus Genotyping (CYP3A5) test is performed using the Real Time PCR method. It falls under the category of therapeutic drug monitoring.

Doctor and Test Department

The TACROLIMUS GENOTYPING CYP3A5 Test is recommended by Nephrologists and Transplant Surgeons. It is conducted in the Molecular Diagnostics department of DNA Labs UAE.

Pre Test Information

No special preparation is required for the TACROLIMUS GENOTYPING CYP3A5 Test.

Conclusion

The TACROLIMUS GENOTYPING CYP3A5 Test offered by DNA Labs UAE is a crucial genetic test for organ transplant patients on long-term tacrolimus therapy. By determining an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects. The test cost is 1220.0 AED, and the sample required is 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. It is performed using the Real Time PCR method in the Molecular Diagnostics department. Nephrologists and Transplant Surgeons recommend this test to ensure proper drug dosing and efficacy.

Test Name TACROLIMUS GENOTYPING CYP3A5 Test
Components
Price 1220.0 AED
Sample Condition 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE.
Report Delivery Sample Mon / Thu by 11 am; Report Wed / Sat
Method Real Time PCR
Test type Therapeutic drug monitoring
Doctor Nephrologist, Transplant surgeon
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information No special preparation required
Test Details

The Tacrolimus Genotyping (CYP3A5) test is a genetic test that determines an individual’s CYP3A5 genotype. The CYP3A5 gene encodes an enzyme that is responsible for the metabolism of tacrolimus, a medication commonly used in organ transplant patients to prevent rejection.

The test helps determine an individual’s ability to metabolize tacrolimus, which can vary depending on their CYP3A5 genotype. There are two common genotypes: CYP3A5 expressers (CYP3A5*1) and non-expressers (CYP3A5*3). CYP3A5 expressers have higher enzyme activity and may require higher doses of tacrolimus for therapeutic levels, while non-expressers have lower enzyme activity and may require lower doses.

By identifying an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects. This test is particularly useful in organ transplant patients who require long-term tacrolimus therapy to ensure proper drug dosing and efficacy.