Sperm DNA Fragmentation DFI Test Price 1970 AED in Dubai

At DNA Labs UAE, we offer the Sperm DNA Fragmentation DFI Test to assess the integrity of the genetic material in sperm cells and identify potential causes of male infertility.

What is Sperm DNA Fragmentation?

Sperm DNA fragmentation refers to the breaking or fragmentation of the DNA strands within sperm cells. This condition can arise due to various factors, including oxidative stress, defective maturation, and abortive apoptosis during spermatogenesis. The integrity of sperm DNA is paramount for successful fertilization and embryo development. High levels of DNA fragmentation can lead to reduced fertility, increased risk of miscarriages, and even chromosomal abnormalities in offspring.

DNA Fragmentation Sperm Test

The DNA Fragmentation Index (DFI) test is a diagnostic tool that measures the percentage of sperm with fragmented DNA. This test is particularly useful for men who have experienced unexplained infertility, recurrent miscarriages, or failed assisted reproductive technology (ART) treatments. By assessing the DFI, healthcare providers can gain valuable insights into the underlying causes of fertility issues and tailor treatment plans accordingly.

How Does the DFI Test Work?

The DFI test involves analyzing a semen sample using sophisticated diagnostic techniques such as the Sperm Chromatin Structure Assay (SCSA), Terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL), or the Sperm Chromatin Dispersion (SCD) test. These methods evaluate the extent of DNA damage by detecting breaks in the DNA strands. The results are then used to determine the DFI, which is expressed as a percentage.

Interpreting DFI Results

Understanding the DFI results is crucial for making informed decisions about fertility treatments. Generally, a DFI of less than 15% is considered normal, while values between 15% and 30% are deemed average. A DFI of more than 30% indicates poor sperm DNA integrity, which can significantly impact fertility outcomes.

Current Trends and Expert Opinions

Recent studies have highlighted the importance of DFI testing in predicting fertility outcomes. For instance, research has shown that high DFI levels are associated with lower pregnancy rates and increased risk of miscarriages. Experts emphasize the need for standardized DFI testing protocols and cut-off values to ensure accurate and reliable results.

Conclusion

For individuals in the UAE struggling with fertility issues, the DFI test offers a valuable diagnostic tool that can help uncover the underlying causes of infertility. By understanding sperm DNA fragmentation and its impact on fertility, couples can make informed decisions about their reproductive health. With the advancements in DFI testing, there is hope for improved fertility outcomes and a brighter future for those seeking to conceive.

Test Details

The Sperm DNA Fragmentation DFI (DNA Fragmentation Index) test is a laboratory test that measures the level of DNA damage in sperm. It assesses the integrity of the genetic material in sperm cells and can help identify potential causes of male infertility.

During the test, sperm cells are isolated from a semen sample and their DNA is extracted. The DNA is then analyzed to determine the percentage of fragmented DNA present. A higher DFI value indicates a higher level of DNA damage in the sperm, which can negatively impact fertility.

Sperm DNA fragmentation can occur due to various factors such as oxidative stress, infections, exposure to toxins, advanced age, or genetic abnormalities. High levels of DNA fragmentation have been associated with decreased sperm quality, reduced sperm motility, and lower pregnancy rates.

The DFI test can be used as a diagnostic tool to assess male fertility potential and guide appropriate treatment options. It can help determine the need for assisted reproductive techniques such as in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI), which can bypass the effects of DNA damage in sperm.

Overall, the Sperm DNA Fragmentation DFI test provides valuable information about the quality of sperm DNA and can aid in the evaluation and management of male infertility.

Test Name:

Sperm DNA Fragmentation DFI Test

Components:

• Price: 1970.0 AED

Sample Condition:

Seminal Fluid

Report Delivery:

Sample Daily by 6 pm; Report 7 Working days

Method:

TUNEL Assay, Fluorescent microscopy

Test Type:

Infertility

Doctor:

Endocrinologist

Test Department:

CYTOGENETICS

Pre Test Information

The sperm DNA fragmentation test checks for the integrity of the genetic material (DNA) in sperm. Many lifestyle factors such as smoking, scrotal heat exposure are causes of male infertility. Varicocele and chronic infection also lead to sperm DNA damage. High DNA fragmentation accounts for cases of unexplained infertility, recurrent miscarriage, and failed IVF cycles.