Test Price
2,800 AED✅ Home Collection Available
SLC17A8 Gene Deafness, Autosomal Dominant Type 25 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Genetic Counseling for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SLC17A8 Gene Deafness Genetic Test is a precision molecular diagnostic that analyzes the entire coding sequence of the SLC17A8 gene to identify pathogenic variants responsible for autosomal dominant nonsyndromic hearing loss (DFNA25). With a turnaround time of 3–4 weeks and the option of VIP home blood collection, it delivers clinically actionable insights for family planning and personalized audiological management.
| Feature | Our Test (NGS – SLC17A8 Gene) | Standard Targeted Sanger Sequencing |
|---|---|---|
| Method | Full‑gene next‑generation sequencing with bioinformatic variant calling | PCR‑based Sanger sequencing of known hot‑spot mutations only |
| Detection Rate | >99.9% of coding variants (including novel mutations) | ~80‑85% – misses rare or novel variants |
| Turnaround Time | 3–4 weeks | 4–6 weeks |
| Clinical Applicability | Comprehensive DFNA25 diagnosis and familial cascade testing | Limited to families with previously characterized variants |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I recognize the profound impact hereditary hearing loss can have on a family's life trajectory. The SLC17A8 gene test provides definitive molecular evidence, enabling early intervention and informed reproductive decisions. However, genetic results must always be integrated with comprehensive audiological and clinical assessments for optimal patient management.”
— Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory & Medication Warning
⚠ Do not discontinue any prescribed medication for hearing loss or any other condition without consulting your treating doctor. Genetic test results do not replace ongoing medical therapy.
Patient Safety – Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Individuals under 18 years without parental consent (per Federal Decree-Law No. 4 of 2016 on Medical Liability); test not suitable for prenatal diagnosis without formal genetic counselling; acute febrile illness at time of home collection.
- Emergency Red Flags – Seek immediate ENT/ER care if: Sudden, severe unilateral hearing loss with vertigo; associated neurological symptoms (facial weakness, dysarthria); acute otalgia with discharge or high fever.
Patient FAQ & Clinical Guidance
1. What does the SLC17A8 genetic test detect?
This test identifies pathogenic variants in the SLC17A8 gene responsible for autosomal dominant hereditary hearing loss DFNA25.
2. How is the test performed and when will I get results?
A certified phlebotomist collects a small blood sample (or buccal swab) at your home via our VIP Mobile Phlebotomy service, and the NGS analysis delivers results in 3–4 weeks.
3. What should I do if the result is positive?
A positive result should be discussed with your ENT specialist and a clinical geneticist for personalized hearing management and family cascade testing.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: All genetic data is handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient information is encrypted and accessible only to authorized clinical staff.
Accreditation & Licensing: DNA Labs UAE operates under DHA Facility License Number 1143. Our laboratory is ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139) and follows international standards for genetic testing.
Clinical & Logistical Metadata
| Test Name | SLC17A8 Gene Deafness (DFNA25) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) or Buccal Swab |
| Methodology Used | Next-Generation Sequencing (NGS) – Full Gene Coding Region Analysis |
| ICD-10-CM Code | H90.5 |
| LOINC Code | 54339-1 |
| DHA Facility License & Laboratory Address | License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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