PDGFRß CMML Test
At DNA Labs UAE, we offer the PDGFRß CMML Test for AED 1050.0. This test is used to diagnose Chronic Myelomonocytic Leukemia (CMML) and involves the analysis of the PDGFR (Platelet-Derived Growth Factor Receptor Beta) gene.
Test Details
The PDGFRß CMML Test is performed using a Sodium Heparin Vacutainer (2ml) and can be done with a doctor’s prescription. It is important to note that the prescription is not applicable for surgery, pregnancy cases, or people planning to travel abroad.
Symptoms and Diagnosis
CMML is a type of cancer that affects the blood and bone marrow. It is characterized by the overproduction of white blood cells, specifically monocytes. The PDGFR gene plays a role in cell growth, division, and survival. Mutations or abnormalities in the PDGFR gene can lead to the overactivation of the PDGFR protein, resulting in uncontrolled cell growth and the development of CMML.
Test Method and Type
The PDGFRß CMML Test is performed using the FISH (Fluorescence In Situ Hybridization) method, which allows for the detection of specific genetic abnormalities. This test falls under the category of Genetics and is conducted by our experienced oncology doctors in our specialized Test Department.
Report Delivery
After the test is conducted, the report will be delivered within 3-4 days.
Treatment Options
In cases where CMML patients have PDGFR mutations, targeted therapies that specifically inhibit PDGFR, such as tyrosine kinase inhibitors, may be used. These drugs can help block the activity of the overactive PDGFR protein and slow down the growth of cancer cells.
If you suspect CMML or have been recommended by your doctor, it is important to get the PDGFRß CMML Test done for an accurate diagnosis. Contact DNA Labs UAE today to schedule an appointment.
| Test Name | PDGFRß CMML Test |
|---|---|
| Components | Sodium Heparin Vacutainer (2ml) |
| Price | 1050.0 AED |
| Sample Condition | Bone Marrow \/ Peripheral blood |
| Report Delivery | 3-4 days |
| Method | FISH |
| Test type | Genetics |
| Doctor | Oncology |
| Test Department: | |
| Pre Test Information | PDGFR (CMML) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details | PDGFR stands for Platelet-Derived Growth Factor Receptor Beta. CMML stands for Chronic Myelomonocytic Leukemia. PDGFR is a receptor protein found on the surface of certain cells, including blood cells. It plays a role in cell growth, division, and survival. When activated, PDGFR can stimulate the growth and proliferation of cells. CMML is a type of cancer that affects the blood and bone marrow. It is characterized by the overproduction of white blood cells, specifically monocytes. CMML is considered a myelodysplastic/myeloproliferative neoplasm, meaning it has features of both myelodysplastic syndromes (MDS) and myeloproliferative neoplasms (MPN). In some cases of CMML, there may be mutations or abnormalities in the PDGFR gene. These mutations can lead to the overactivation of the PDGFR protein, resulting in uncontrolled cell growth and the development of CMML. Targeted therapies that specifically inhibit PDGFR, such as tyrosine kinase inhibitors, may be used in the treatment of CMML patients with PDGFR mutations. These drugs can help block the activity of the overactive PDGFR protein and slow down the growth of cancer cells. |
