PDGFR Mutation Screening Exons 12 14 18 Test
Are you concerned about potential mutations in the PDGFR gene? DNA Labs UAE offers the PDGFR Mutation Screening Exons 12 14 18 Test to help diagnose and understand certain diseases associated with PDGFR gene mutations.
Test Details
The PDGFR Mutation Screening Exons 12 14 18 Test focuses on specific regions (exons) of the PDGFR gene. By screening for mutations in exons 12, 14, and 18, healthcare professionals can identify changes in the DNA sequence that may be associated with disease development or progression. Mutations in the PDGFR gene can lead to abnormal activation of the receptor, which is linked to various types of cancer, including gastrointestinal stromal tumors (GISTs) and chronic myelomonocytic leukemia (CMML).
Components
- Paraffin embedded tissue blocks
Test Type
Genetics
Sample Condition
Tumor tissue
Report Delivery
7-8 days
Method
Sanger Sequencing
Test Cost
AED 2400.0
Doctor
Gynecologist
Test Department
Pre Test Information
Pre Test Information
PDGFR Mutation Screening (Exons 12, 14, 18) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Importance of PDGFR Mutation Screening
PDGFR is a receptor tyrosine kinase that plays a crucial role in cell growth, proliferation, and differentiation. By identifying PDGFR mutations in exons 12, 14, and 18, healthcare professionals can better understand the genetic basis of certain diseases and tailor treatment strategies accordingly. Targeted therapies that specifically inhibit the abnormal PDGFR signaling pathway can be used to treat patients with PDGFR-mutated cancers.
Don’t wait any longer. Contact DNA Labs UAE today to schedule your PDGFR Mutation Screening Exons 12 14 18 Test and take control of your health.
| Test Name | PDGFR Mutation Screening Exons 12 14 18 Test |
|---|---|
| Components | Paraffin embedded tissue blocks |
| Price | 2400.0 AED |
| Sample Condition | Tumor tissue |
| Report Delivery | 7-8 days |
| Method | Sanger Sequencing |
| Test type | Genetics |
| Doctor | Gynecologist |
| Test Department: | |
| Pre Test Information | PDGFR Mutation Screening (Exons 12, 14, 18) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Test Details |
PDGFR mutation screening refers to the process of testing for mutations in specific exons of the PDGFR (Platelet-Derived Growth Factor Receptor) gene. In this case, the screening focuses on exons 12, 14, and 18 of the PDGFR gene. PDGFR is a receptor tyrosine kinase that plays a crucial role in cell growth, proliferation, and differentiation. Mutations in the PDGFR gene can lead to abnormal activation of the receptor, which is associated with various types of cancer, such as gastrointestinal stromal tumors (GISTs) and chronic myelomonocytic leukemia (CMML). Exons are specific regions of the gene that contain the coding sequence, which is responsible for producing the protein. By screening for mutations in exons 12, 14, and 18 of the PDGFR gene, researchers can identify specific changes in the DNA sequence that may be associated with disease development or progression. The screening process typically involves extracting DNA from patient samples, amplifying the target exons using polymerase chain reaction (PCR), and then sequencing the amplified DNA to detect any mutations. Various techniques, such as Sanger sequencing or next-generation sequencing (NGS), can be used for this purpose. By identifying PDGFR mutations in exons 12, 14, and 18, healthcare professionals can better understand the genetic basis of certain diseases and tailor treatment strategies accordingly. For example, targeted therapies that specifically inhibit the abnormal PDGFR signaling pathway can be used to treat patients with PDGFR-mutated cancers. |
