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Nx Gen Sequencing Familial Hemiplegic Migraine Test Cost

Original price was: 5,200 د.إ.Current price is: 4,680 د.إ.

-10%

The Nx Gen Sequencing Familial Hemiplegic Migraine Test is a cutting-edge diagnostic tool offered by DNA Labs UAE, designed to identify genetic mutations associated with Familial Hemiplegic Migraine (FHM). FHM is a rare subtype of migraine with aura, characterized by temporary weakness on one side of the body, in addition to the typical migraine symptoms. This condition is inherited in an autosomal dominant pattern, meaning a mutation in just one of the two copies of the gene in each cell is sufficient to cause the disorder.

Utilizing Next-Generation Sequencing (NGS) technology, this test comprehensively analyzes the genes known to be linked with FHM, including CACNA1A, ATP1A2, and SCN1A. NGS allows for the simultaneous sequencing of millions of DNA fragments, ensuring a highly sensitive and accurate identification of genetic variations that could predispose individuals to FHM.

The test is priced at 4680 AED and is conducted at DNA Labs UAE, a facility renowned for its state-of-the-art genetic testing services. By opting for this test, individuals with a family history of FHM can gain valuable insights into their genetic predisposition to the condition. This information can be crucial for early diagnosis, personalized treatment plans, and preventive strategies, ultimately enhancing the quality of life for those affected by or at risk of familial hemiplegic migraine.

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  • This test is not intended for medical diagnosis or treatment
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Nx GEN SEQUENCING FAMILIAL HEMIPLEGIC MIGRAINE Test

Test Cost: AED 4680.0

Symptoms and Diagnosis

Familial hemiplegic migraine (FHM) is a rare genetic disorder that causes severe migraines along with temporary paralysis or weakness on one side of the body. It is an inherited condition, and genetic testing can be used to identify specific gene mutations associated with FHM.

Test Components

  • ATP1A2
  • CACNA1A
  • PRRT2
  • SCN1A

Price: AED 4680.0

Sample Condition

Submit 10 mL (5 mL min.) whole blood from 2 Lavender Top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.

Report Delivery

Sample Daily by 9 am; Report 40 Working days

Method

NGS, Sanger sequencing

Test Type

Genetic Disorders-Migraine

Doctor

Neurologist

Test Department

MOLECULAR DIAGNOSTICS

Pre Test Information

Duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.

Test Details

Familial hemiplegic migraine (FHM) is a rare genetic disorder that causes severe migraines along with temporary paralysis or weakness on one side of the body. It is an inherited condition, and genetic testing can be used to identify specific gene mutations associated with FHM.

Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that allows for the simultaneous sequencing of multiple genes or even entire genomes. In the case of FHM, NGS can be used to analyze a panel of genes known to be associated with the condition.

The FHM test using NGS involves collecting a DNA sample, usually through a blood sample or saliva sample. The DNA is then extracted and purified in the laboratory. Next, the specific genes associated with FHM are amplified using polymerase chain reaction (PCR) or other techniques. The amplified DNA fragments are then sequenced using NGS technology.

The sequencing data obtained from NGS is analyzed using specialized software to identify any genetic variations or mutations in the FHM-associated genes. These variations can help determine if a person has a genetic predisposition to FHM.

The results of the NGS test for FHM can provide valuable information for diagnosis, genetic counseling, and treatment planning. It can help confirm a clinical diagnosis of FHM, identify the specific gene mutation responsible for the condition, and assess the risk of passing the condition on to future generations.

It is important to note that genetic testing for FHM using NGS may not be available in all healthcare settings and may require consultation with a genetic counselor or specialist. Additionally, while genetic testing can provide valuable information, it is not a standalone diagnostic tool, and clinical evaluation by a healthcare professional is still necessary for an accurate diagnosis of FHM.

Test Name Nx GEN SEQUENCING FAMILIAL HEMIPLEGIC MIGRAINE Test
Components ATP1A2, CACNA1A, PRRT2, SCN1A
Price 4680.0 AED
Sample Condition Submit 10 mL (5 mL min.) whole blood from 2 Lavender Top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.
Report Delivery Sample Daily by 9 am; Report 40 Working days
Method NGS, Sanger sequencing
Test type Genetic Disorders-Migraine
Doctor Neurologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.
Test Details

Familial hemiplegic migraine (FHM) is a rare genetic disorder that causes severe migraines along with temporary paralysis or weakness on one side of the body. It is an inherited condition, and genetic testing can be used to identify specific gene mutations associated with FHM.

Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that allows for the simultaneous sequencing of multiple genes or even entire genomes. In the case of FHM, NGS can be used to analyze a panel of genes known to be associated with the condition.

The FHM test using NGS involves collecting a DNA sample, usually through a blood sample or saliva sample. The DNA is then extracted and purified in the laboratory. Next, the specific genes associated with FHM are amplified using polymerase chain reaction (PCR) or other techniques. The amplified DNA fragments are then sequenced using NGS technology.

The sequencing data obtained from NGS is analyzed using specialized software to identify any genetic variations or mutations in the FHM-associated genes. These variations can help determine if a person has a genetic predisposition to FHM.

The results of the NGS test for FHM can provide valuable information for diagnosis, genetic counseling, and treatment planning. It can help confirm a clinical diagnosis of FHM, identify the specific gene mutation responsible for the condition, and assess the risk of passing the condition on to future generations.

It is important to note that genetic testing for FHM using NGS may not be available in all healthcare settings and may require consultation with a genetic counselor or specialist. Additionally, while genetic testing can provide valuable information, it is not a standalone diagnostic tool, and clinical evaluation by a healthcare professional is still necessary for an accurate diagnosis of FHM.

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