NRAS Mutation Analysis codons 12 and 13 Test
Welcome to DNA Labs UAE, your trusted genetic lab. In this blog, we will discuss the NRAS Mutation Analysis codons 12 and 13 Test, including its cost, symptoms, diagnosis, and more.
Test Details
The NRAS gene is a proto-oncogene that codes for a protein involved in cell signaling pathways. Mutations in this gene can lead to the activation of the NRAS protein, which can contribute to the development of various cancers, including melanoma, colorectal cancer, and thyroid cancer. Codons 12 and 13 of the NRAS gene are hotspots for mutations.
The most common mutation in these codons is a substitution of the amino acid glycine for aspartic acid (G12D) or cysteine (G12C). Other mutations at these codons include substitutions of glycine for valine (G12V), serine (G12S), or arginine (G12R).
NRAS mutation analysis involves testing for the presence of these mutations in tumor samples. This analysis can be done using various techniques, including polymerase chain reaction (PCR) and DNA sequencing.
By identifying NRAS mutations, healthcare providers can determine the most appropriate treatment options for patients with cancer, as certain targeted therapies are available for individuals with specific NRAS mutations.
Test Components
- Paraffin embedded tissue blocks
Price
The cost of the NRAS Mutation Analysis codons 12 and 13 Test is 2100.0 AED.
Sample Condition
Tumor tissue
Report Delivery
The report will be delivered within 7-8 days.
Method
Sanger Sequencing
Test Type
Genetics
Doctor
Gynecologist
Test Department
Pre Test Information
Pre Test Information
NRAS Mutation Analysis (codons 12 & 13) can be done with a doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Thank you for choosing DNA Labs UAE for your genetic testing needs. If you have any further questions or would like to schedule an appointment, please contact us.
Test Name | NRAS Mutation Analysis codons 12 and 13 Test |
---|---|
Components | Paraffin embedded tissue blocks |
Price | 2100.0 AED |
Sample Condition | Tumor tissue |
Report Delivery | 7-8 days |
Method | Sanger Sequencing |
Test type | Genetics |
Doctor | Gynecologist |
Test Department: | |
Pre Test Information | NRAS Mutation Analysis (codons 12 & 13) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
Test Details |
The NRAS gene is a proto-oncogene that codes for a protein involved in cell signaling pathways. Mutations in this gene can lead to the activation of the NRAS protein, which can contribute to the development of various cancers, including melanoma, colorectal cancer, and thyroid cancer. Codons 12 and 13 of the NRAS gene are hotspots for mutations. The most common mutation in these codons is a substitution of the amino acid glycine for aspartic acid (G12D) or cysteine (G12C). Other mutations at these codons include substitutions of glycine for valine (G12V), serine (G12S), or arginine (G12R). NRAS mutation analysis involves testing for the presence of these mutations in tumor samples. This analysis can be done using various techniques, including polymerase chain reaction (PCR) and DNA sequencing. By identifying NRAS mutations, healthcare providers can determine the most appropriate treatment options for patients with cancer, as certain targeted therapies are available for individuals with specific NRAS mutations. |