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NPM1 Mutation Analysis Exon 12 Insertion Test Cost

Original price was: 1,600 د.إ.Current price is: 1,200 د.إ.

-25%

The NPM1 Mutation Analysis Exon 12 Insertion Test is a specialized diagnostic procedure aimed at detecting mutations within exon 12 of the Nucleophosmin 1 (NPM1) gene. These mutations are significant because they are frequently observed in patients with acute myeloid leukemia (AML), a type of cancer that affects the blood and bone marrow. Identifying the presence of NPM1 mutations is crucial for the prognosis, treatment planning, and monitoring of AML patients, as these mutations are associated with distinct clinical outcomes and may influence the response to certain therapies.

Performed at DNA Labs UAE, a leading laboratory renowned for its advanced genetic testing capabilities, this test involves analyzing the patient’s DNA to search for the specific insertion mutations within exon 12 of the NPM1 gene. The procedure is conducted under strict quality controls to ensure accuracy and reliability of the results.

The cost of the NPM1 Mutation Analysis Exon 12 Insertion Test at DNA Labs UAE is set at 1200 AED. This price reflects the intricate nature of the testing process and the valuable insights it provides to healthcare providers, helping them to tailor treatment strategies that are more effective for patients with AML. By offering this test, DNA Labs UAE contributes to the personalized approach in cancer treatment, enabling better patient care and outcomes.

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NPM1 Mutation Analysis Exon 12 Insertion Test

Test Name: NPM1 Mutation Analysis Exon 12 Insertion Test

Components: EDTA Vacutainer (2ml)

Price: 1200.0 AED

Sample Condition: Bone Marrow/Peripheral Blood

Report Delivery: 7-8 days

Method: Sanger Sequencing

Test Type: Genetics

Doctor: Gynecologist

Test Department:

Pre Test Information: NPM1 Mutation Analysis (Exon 12 insertion) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.

Test Details

NPM1 mutation analysis refers to the testing and analysis of mutations in the NPM1 gene. The NPM1 gene is responsible for producing the nucleophosmin protein, which is involved in various cellular processes, including cell growth and division. One specific type of NPM1 mutation is the exon 12 insertion mutation. This mutation involves the insertion of a small piece of DNA sequence into exon 12 of the NPM1 gene.

This mutation is commonly found in patients with acute myeloid leukemia (AML) and is associated with a favorable prognosis. To perform NPM1 mutation analysis, a sample of the patient’s blood or bone marrow is collected. The DNA is then extracted from the sample and specific regions of the NPM1 gene, including exon 12, are amplified using a technique called polymerase chain reaction (PCR). The amplified DNA is then sequenced to identify any mutations, including the exon 12 insertion mutation.

The results of NPM1 mutation analysis can help in the diagnosis and prognosis of AML. Patients with the exon 12 insertion mutation have been shown to have a better response to certain chemotherapy treatments and a higher chance of achieving complete remission. In summary, NPM1 mutation analysis, specifically for the exon 12 insertion mutation, is a diagnostic and prognostic tool used in the management of AML.

Test Name NPM1 Mutation Analysis Exon 12 insertion Test
Components EDTA Vacutainer (2ml)
Price 1200.0 AED
Sample Condition Bone Marrow\/Peripheral Blood
Report Delivery 7-8 days
Method Sanger Sequencing
Test type Genetics
Doctor Gynecologist
Test Department:
Pre Test Information NPM1 Mutation Analysis (Exon 12 insertion) can be done with a Doctors prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.
Test Details

NPM1 mutation analysis refers to the testing and analysis of mutations in the NPM1 gene. The NPM1 gene is responsible for producing the nucleophosmin protein, which is involved in various cellular processes, including cell growth and division.

One specific type of NPM1 mutation is the exon 12 insertion mutation. This mutation involves the insertion of a small piece of DNA sequence into exon 12 of the NPM1 gene. This mutation is commonly found in patients with acute myeloid leukemia (AML) and is associated with a favorable prognosis.

To perform NPM1 mutation analysis, a sample of the patient’s blood or bone marrow is collected. The DNA is then extracted from the sample and specific regions of the NPM1 gene, including exon 12, are amplified using a technique called polymerase chain reaction (PCR). The amplified DNA is then sequenced to identify any mutations, including the exon 12 insertion mutation.

The results of NPM1 mutation analysis can help in the diagnosis and prognosis of AML. Patients with the exon 12 insertion mutation have been shown to have a better response to certain chemotherapy treatments and a higher chance of achieving complete remission.

In summary, NPM1 mutation analysis, specifically for the exon 12 insertion mutation, is a diagnostic and prognostic tool used in the management of AML.