NOTCH3 MUTATION DETECTION CADASIL Test
Welcome to DNA Labs UAE, where we offer the NOTCH3 MUTATION DETECTION CADASIL Test. This genetic test is designed to detect mutations in the NOTCH3 gene, which is associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
Test Details
The NOTCH3 mutation detection CADASIL test is used to identify any mutations or changes in the NOTCH3 gene. This test is typically ordered by a healthcare professional, such as a neurologist or geneticist, who specializes in diagnosing and managing CADASIL.
Components
- NOTCH3 Gene
Price
The cost of the NOTCH3 MUTATION DETECTION CADASIL Test is 2340.0 AED.
Sample Condition
4 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery
Sample collected on Monday by 11 am will have the report delivered on Friday.
Method
The NOTCH3 MUTATION DETECTION CADASIL Test is performed using PCR (Polymerase Chain Reaction) and sequencing techniques.
Test Type
This test falls under the category of Neurologic Disorder.
Doctor
This test is typically ordered by a Neurologist.
Test Department
This test is conducted in the Molecular Diagnostics department.
Pre Test Information
A duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory prior to the test.
About CADASIL
CADASIL is a hereditary condition that affects the small blood vessels in the brain. It can lead to recurrent strokes, cognitive decline, and other neurological symptoms.
Importance of NOTCH3 Mutation Detection
Detecting a NOTCH3 mutation is crucial for both diagnostic and genetic counseling purposes. It allows individuals with CADASIL to receive appropriate medical management and treatment. Additionally, it helps identify at-risk family members who may benefit from genetic testing or counseling.
It’s important to note that the test results should be interpreted in conjunction with the individual’s clinical symptoms and family history.
| Test Name | NOTCH3 MUTATION DETECTION CADASIL Test |
|---|---|
| Components | *NOTCH3 Gene |
| Price | 2340.0 AED |
| Sample Condition | 4 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. |
| Report Delivery | Sample Mon by 11 am; Report Fri |
| Method | PCR, Sequencing |
| Test type | Neurologic Disorder |
| Doctor | Neurologist |
| Test Department: | MOLECULAR DIAGNOSTICS |
| Pre Test Information | Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. |
| Test Details |
The NOTCH3 mutation detection CADASIL test is a genetic test used to detect mutations in the NOTCH3 gene, which is associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). CADASIL is a hereditary condition that affects the small blood vessels in the brain, leading to recurrent strokes, cognitive decline, and other neurological symptoms. The test involves analyzing a person’s DNA sample, typically obtained through a blood sample, to identify any mutations or changes in the NOTCH3 gene. This can help confirm a diagnosis of CADASIL and provide information about the specific genetic variant present. Detection of a NOTCH3 mutation can be important for both diagnostic and genetic counseling purposes. It allows individuals with CADASIL to receive appropriate medical management and treatment, as well as helps identify at-risk family members who may benefit from genetic testing or counseling. It’s important to note that this test is typically ordered by a healthcare professional, such as a neurologist or geneticist, who specializes in diagnosing and managing CADASIL. The test results should be interpreted in conjunction with the individual’s clinical symptoms and family history. |
