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Myeloproliferative Neoplasia MPN Extended Profile Test

Original price was: 3,120 د.إ.Current price is: 2,810 د.إ.

-10%

The Myeloproliferative Neoplasia (MPN) Extended Profile Test is a specialized diagnostic examination designed to detect and analyze genetic mutations associated with myeloproliferative disorders. These disorders are a group of blood cancers that occur when the bone marrow, responsible for producing blood cells, works abnormally, leading to an excessive production of one or more types of blood cells. The MPN Extended Profile Test targets specific genes known to be involved in these conditions, such as JAK2, CALR, and MPL mutations, among others, providing crucial information for accurate diagnosis, prognosis, and guiding treatment strategies.

Conducted at DNA Labs UAE, a leading facility in genetic and molecular diagnostics, the test employs advanced genomic technologies to ensure high sensitivity and specificity in detecting relevant mutations. Given the complexity of MPN and its significant variability among patients, this test plays a vital role in personalized medicine, allowing healthcare providers to tailor treatments according to the genetic makeup of each individual’s disease.

The cost of the MPN Extended Profile Test at DNA Labs UAE is 2,810 AED. This price reflects the comprehensive nature of the test, covering a broad spectrum of genetic markers to provide a detailed profile of the myeloproliferative neoplasm. Patients and healthcare providers considering this test should note that the investment in such detailed diagnostic tools can be invaluable in managing these complex conditions effectively, potentially leading to better outcomes and quality of life for patients.

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MYELOPROLIFERATIVE NEOPLASIA MPN EXTENDED PROFILE Test

Test Cost: AED 2810.0

Symptoms and Diagnosis:

The MYELOPROLIFERATIVE NEOPLASIA (MPN) EXTENDED PROFILE test is a comprehensive diagnostic tool used to evaluate and monitor patients with suspected or confirmed myeloproliferative neoplasms (MPNs). MPNs are a group of rare blood disorders characterized by the overproduction of blood cells in the bone marrow.

The MPN EXTENDED PROFILE test includes the following components:

  1. Complete Blood Count (CBC): This test measures the levels of red blood cells, white blood cells, and platelets in the blood. Abnormalities in these cell counts can indicate the presence of an MPN.
  2. Bone Marrow Aspiration and Biopsy: This procedure involves the extraction of a small sample of bone marrow tissue for microscopic examination. It helps determine the presence of abnormal cells and assess the overall health of the bone marrow.
  3. JAK2 V617F Mutation Analysis: The JAK2 gene mutation is commonly associated with MPNs, particularly polycythemia vera (PV) and essential thrombocythemia (ET). This test detects the presence of the JAK2 V617F mutation in the patient’s blood or bone marrow sample.
  4. CALR Mutation Analysis: CALR gene mutations are also frequently found in MPNs, particularly essential thrombocythemia (ET) and primary myelofibrosis (PMF). This test identifies the presence of CALR mutations in the patient’s blood or bone marrow sample.
  5. MPL Mutation Analysis: MPL gene mutations are less common but can be present in some MPN cases, particularly primary myelofibrosis (PMF). This test detects the presence of MPL mutations in the patient’s blood or bone marrow sample.
  6. Additional Molecular Testing: Depending on the specific MPN suspected, additional molecular tests may be included to identify other gene mutations associated with MPNs, such as ASXL1, TET2, or IDH1/2 mutations.

The results of the MPN EXTENDED PROFILE test help healthcare providers establish a definitive diagnosis, classify the specific MPN subtype, and guide treatment decisions. Regular monitoring of these markers can also help assess disease progression and response to therapy.

Test Details:

Sample Condition: 8 mL (4 mL min.) whole blood in 2 Lavender top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Report Delivery: SampleMon by 9 am; Report Sat

Method: Real Time PCR, Sequencing

Test Type: Cancer

Doctor: Hematologist, Oncologist

Test Department: MOLECULAR DIAGNOSTICS

Pre Test Information: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

For more information or to schedule an appointment, please contact DNA Labs UAE.

Test Name MYELOPROLIFERATIVE NEOPLASIA MPN EXTENDED PROFILE Test
Components *Jak2 V617F*Jak2 Exon 12*BCR-ABL PCR Qualitative*CALR*MPL
Price 2810.0 AED
Sample Condition 8 mL (4 mL min.) whole blood in 2 Lavender top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery SampleMon by 9 am; Report Sat
Method Real Time PCR, Sequencing
Test type Cancer
Doctor Hematologist, Oncologist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Test Details

The MYELOPROLIFERATIVE NEOPLASIA (MPN) EXTENDED PROFILE test is a comprehensive diagnostic tool used to evaluate and monitor patients with suspected or confirmed myeloproliferative neoplasms (MPNs). MPNs are a group of rare blood disorders characterized by the overproduction of blood cells in the bone marrow.

The MPN EXTENDED PROFILE test includes the following components:

1. Complete Blood Count (CBC): This test measures the levels of red blood cells, white blood cells, and platelets in the blood. Abnormalities in these cell counts can indicate the presence of an MPN.

2. Bone Marrow Aspiration and Biopsy: This procedure involves the extraction of a small sample of bone marrow tissue for microscopic examination. It helps determine the presence of abnormal cells and assess the overall health of the bone marrow.

3. JAK2 V617F Mutation Analysis: The JAK2 gene mutation is commonly associated with MPNs, particularly polycythemia vera (PV) and essential thrombocythemia (ET). This test detects the presence of the JAK2 V617F mutation in the patient’s blood or bone marrow sample.

4. CALR Mutation Analysis: CALR gene mutations are also frequently found in MPNs, particularly essential thrombocythemia (ET) and primary myelofibrosis (PMF). This test identifies the presence of CALR mutations in the patient’s blood or bone marrow sample.

5. MPL Mutation Analysis: MPL gene mutations are less common but can be present in some MPN cases, particularly primary myelofibrosis (PMF). This test detects the presence of MPL mutations in the patient’s blood or bone marrow sample.

6. Additional Molecular Testing: Depending on the specific MPN suspected, additional molecular tests may be included to identify other gene mutations associated with MPNs, such as ASXL1, TET2, or IDH1/2 mutations.

The results of the MPN EXTENDED PROFILE test help healthcare providers establish a definitive diagnosis, classify the specific MPN subtype, and guide treatment decisions. Regular monitoring of these markers can also help assess disease progression and response to therapy.

SKU: TEST-4824 Category:

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