MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test
At DNA Labs UAE, we offer the MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test for individuals suspected to have mitochondrial complex I deficiency. This genetic test analyzes the MT-ND3 gene, which is responsible for encoding a subunit of the mitochondrial complex I enzyme.
Test Components and Price
The cost of the MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test is AED 4400.0. The test requires a blood sample or extracted DNA. Alternatively, one drop of blood can be collected on an FTA card.
Report Delivery
After the sample is received, the report will be delivered within 3 to 4 weeks.
Testing Method
The MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test utilizes NGS (Next-Generation Sequencing) technology. This advanced sequencing method allows for the simultaneous analysis of multiple genes.
Test Type
The MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test is specifically designed to diagnose neurological disorders.
Referring Doctor and Test Department
This test is recommended for individuals who have been referred by a neurologist. The test is conducted in the Genetics department of DNA Labs UAE.
Pre Test Information
Prior to the test, a clinical history of the patient is required. This information helps in understanding the patient’s symptoms and medical background. Additionally, a genetic counseling session may be conducted to draw a pedigree chart of family members affected by MT-ND3 Gene Mitochondrial complex I deficiency.
Test Details
The MT-ND3 gene is a crucial component of the mitochondrial DNA (mtDNA) and is responsible for the production of ATP, which is essential for cellular energy. A deficiency in the MT-ND3 gene can lead to mitochondrial complex I deficiency, a rare genetic disorder. This deficiency affects the normal functioning of the electron transport chain and reduces ATP production.
Individuals with mitochondrial complex I deficiency may experience various symptoms, including muscle weakness, exercise intolerance, developmental delay, intellectual disability, seizures, and organ dysfunction.
The NGS genetic testing method used in this test allows for the identification of mutations or variations in the MT-ND3 gene and other genes associated with mitochondrial complex I deficiency. This testing helps confirm a diagnosis, identify the specific genetic cause of the disorder, and guide treatment options and genetic counseling.
| Test Name | MT-ND3 Gene Mitochondrial complex I deficiency Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Neurological Disorders |
| Doctor | Neurologist |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for MT-ND3 Gene Mitochondrial complex I deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MT-ND3 Gene Mitochondrial complex I deficiency |
| Test Details |
The MT-ND3 gene is a gene found in the mitochondrial DNA (mtDNA) and encodes for a subunit of the mitochondrial complex I enzyme. Mitochondrial complex I is responsible for the first step in the electron transport chain, which is crucial for the production of ATP (cellular energy). A deficiency in the MT-ND3 gene can lead to mitochondrial complex I deficiency, which is a rare genetic disorder. This deficiency impairs the normal functioning of the electron transport chain and reduces the production of ATP. As a result, affected individuals may experience a wide range of symptoms, including muscle weakness, exercise intolerance, developmental delay, intellectual disability, seizures, and organ dysfunction. NGS (Next-Generation Sequencing) genetic testing is a type of genetic test that uses advanced sequencing technologies to analyze multiple genes simultaneously. In the context of mitochondrial complex I deficiency, NGS genetic testing can be used to identify mutations or variations in the MT-ND3 gene and other genes associated with mitochondrial complex I deficiency. This testing can help in confirming a diagnosis, identifying the specific genetic cause of the disorder, and guiding treatment options and genetic counseling. |
