MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS) PANEL Test
The MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS) PANEL test is a diagnostic tool used to detect and monitor a condition called monoclonal gammopathy of undetermined significance (MGUS).
MGUS is a relatively common condition in which abnormal plasma cells produce an excess of a specific type of antibody called monoclonal protein or M protein.
The MGUS PANEL test typically includes several components:
- Serum protein electrophoresis (SPEP): This test separates the different types of proteins in the blood and helps identify any abnormal protein bands that may indicate the presence of MGUS.
- Immunofixation electrophoresis (IFE): This test is used to further characterize any abnormal protein bands detected in the SPEP. It helps determine the specific type of M protein present.
- Serum free light chain assay (FLC): This test measures the levels of free light chains, which are components of antibodies, in the blood. An abnormal ratio of kappa to lambda light chains may indicate MGUS.
- Quantitative immunoglobulins: This test measures the levels of different types of immunoglobulins (IgG, IgA, IgM) in the blood. MGUS may cause an abnormal increase or decrease in these levels.
The MGUS PANEL test is typically ordered when a patient presents with symptoms such as unexplained bone pain, fatigue, recurrent infections, or kidney damage. It is also used to monitor the progression of MGUS over time, as it has the potential to progress to more serious conditions like multiple myeloma.
It is important to note that the MGUS PANEL test is not a definitive diagnostic test for MGUS or related conditions. Further testing, such as bone marrow biopsy, may be necessary to confirm a diagnosis. Additionally, regular monitoring is recommended for patients with MGUS to detect any progression or development of related disorders.
Test Details:
- Test Name: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE MGUS PANEL Test
- Components:
- Protein Electrophoresis, Serum
- Immunotyping, Serum
- Kappa / Lambda Light chains Free, Serum
- Price: 1640.0 AED
- Sample Condition: 3 mL (2 mL min.) serum from 1 SST. Ship refrigerated or frozen. Grossly hemolysed samples not acceptable.
- Report Delivery: Sample Daily by 9 am; Report Next day
- Method: Capillary Electrophoresis, Agarose Gel Electrophoresis, Immunofixation, Nephelometry
- Test Type: Multiple Myeloma
- Doctor: Hematologist, Nephrologist, Oncologist
- Test Department: ELECTROPHORESIS
- Pre Test Information: No special preparation required
Test Name | MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE MGUS PANEL Test |
---|---|
Components | *Protein Electrophoresis, Serum *Immunotyping, Serum *Kappa / Lambda Light chains Free, Serum |
Price | 1640.0 AED |
Sample Condition | 3 mL (2 mL min.) serum from 1 SST. Shiprefrigeratedorfrozen. Grossly hemolysedsamplesnotacceptable. |
Report Delivery | Sample Daily by 9 am; Report Next day |
Method | Capillary Electrophoresis, Agarose Gel Electrophoresis, Immunofixation, Nephelometry |
Test type | Multiple Myeloma |
Doctor | Hematologist, Nephrologist, Oncologist |
Test Department: | ELECTROPHORESIS |
Pre Test Information | No special preparation required |
Test Details |
The MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE (MGUS) PANEL test is a diagnostic tool used to detect and monitor a condition called monoclonal gammopathy of undetermined significance (MGUS). MGUS is a relatively common condition in which abnormal plasma cells produce an excess of a specific type of antibody called monoclonal protein or M protein. The MGUS PANEL test typically includes several components: 1. Serum protein electrophoresis (SPEP): This test separates the different types of proteins in the blood and helps identify any abnormal protein bands that may indicate the presence of MGUS. 2. Immunofixation electrophoresis (IFE): This test is used to further characterize any abnormal protein bands detected in the SPEP. It helps determine the specific type of M protein present. 3. Serum free light chain assay (FLC): This test measures the levels of free light chains, which are components of antibodies, in the blood. An abnormal ratio of kappa to lambda light chains may indicate MGUS. 4. Quantitative immunoglobulins: This test measures the levels of different types of immunoglobulins (IgG, IgA, IgM) in the blood. MGUS may cause an abnormal increase or decrease in these levels. The MGUS PANEL test is typically ordered when a patient presents with symptoms such as unexplained bone pain, fatigue, recurrent infections, or kidney damage. It is also used to monitor the progression of MGUS over time, as it has the potential to progress to more serious conditions like multiple myeloma. It is important to note that the MGUS PANEL test is not a definitive diagnostic test for MGUS or related conditions. Further testing, such as bone marrow biopsy, may be necessary to confirm a diagnosis. Additionally, regular monitoring is recommended for patients with MGUS to detect any progression or development of related disorders. |