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Lupus Anticoagulant Panel LAC Panel Test

640 د.إ

-10%

The Lupus Anticoagulant Panel, commonly abbreviated as LAC Panel Test, is a specialized blood test designed to detect the presence of lupus anticoagulants in the blood. Lupus anticoagulants are antibodies associated with an increased risk of blood clots; these antibodies can interfere with the normal clotting process, leading to complications such as deep vein thrombosis, stroke, or miscarriage. This test is particularly important for individuals suspected of having antiphospholipid syndrome (APS) or those with a history of unexplained blood clotting events.

The test is conducted by drawing a blood sample from the patient, which is then analyzed in a laboratory setting. The LAC Panel Test involves a series of assays to confirm the presence and activity of lupus anticoagulants, making it a crucial tool in diagnosing conditions related to abnormal clotting and autoimmune disorders.

In the United Arab Emirates, DNA Labs UAE offers the Lupus Anticoagulant Panel Test with a cost of 640 AED. DNA Labs UAE is known for its state-of-the-art facilities and adherence to international standards in medical testing, ensuring accurate and reliable results. Patients seeking to undergo the LAC Panel Test at DNA Labs UAE can expect professional service and comprehensive support throughout the testing process.

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LUPUS ANTICOAGULANT PANEL (LAC PANEL) Test

Test Name: LUPUS ANTICOAGULANT PANEL (LAC PANEL) Test

Components: APTT, PTT-LA, dRVVT

Price: 640.0 AED

Sample Condition: 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Report Delivery: Sample Daily by 3 pm; Report Next day

Method: Electromechanical Clot Detection

Test Type: Thromboembolic disorders

Doctor: Hematologist

Test Department: Pre Test Information

Overnight fasting is preferred. It is recommended that the patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling as these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Test Details

The LUPUS ANTICOAGULANT PANEL, also known as the LAC PANEL test, is a series of laboratory tests used to diagnose lupus anticoagulant (LA), which is an autoimmune disorder that causes abnormal blood clotting. The LAC PANEL test typically includes the following tests:

  1. Activated Partial Thromboplastin Time (aPTT): This test measures the time it takes for blood to clot. In the presence of lupus anticoagulant, the aPTT is prolonged.
  2. Dilute Russell Viper Venom Time (dRVVT): This test is similar to the aPTT but uses a specific reagent derived from a snake venom. It is more sensitive in detecting lupus anticoagulant.
  3. Platelet Neutralization Procedure (PNP): This test is used to confirm the presence of lupus anticoagulant by neutralizing the anticoagulant activity of patient plasma with normal platelets.
  4. Hexagonal Phase Phospholipid Neutralization (HexPhos): This test is used to detect lupus anticoagulant by neutralizing the anticoagulant activity of patient plasma with hexagonal phase phospholipids.
  5. Confirmation Testing: If the initial screening tests are positive, additional confirmatory tests may be performed, such as mixing studies or specific factor assays.

The LAC PANEL test is ordered when a patient presents with symptoms of abnormal blood clotting, such as deep vein thrombosis or recurrent miscarriages. It is important to note that a positive LAC PANEL test does not necessarily mean the patient has lupus, as lupus anticoagulant can be found in other autoimmune diseases and even in healthy individuals. Therefore, further clinical evaluation is necessary to make a definitive diagnosis.

Test Name LUPUS ANTICOAGULANT PANEL LAC PANEL Test
Components *APTT*PTT-LA*dRVVT
Price 640.0 AED
Sample Condition 3 mL whole blood in 1 Blue Top (Sodium Citrate) tube. Mix thoroughly by inversion. Transport to Lab within 4 hours. If this is not possible, make PPP within 1 hour of collection as follows: Centrifuge sample at 3600 rpm for 15 min. & transfer supernatant to a clean plastic tube. Centrifuge this supernatant again at 3600 rpm for 15 min. & finally transfer the supernatant (PPP) to 1 labelled clean plastic screw capped vial. FREEZE IMMEDIATELY. Ship frozen. DO NOT THAW. Overnight fasting is preferred. Duly filled Coagulation Requisition Form(Form 15) is mandatory.
Report Delivery Sample Daily by 3 pm; Report Next day
Method Electromechanical Clot Detection
Test type Thromboembolic disorders
Doctor Hematologist
Test Department:
Pre Test Information Overnight fasting is preferred. It is recommended that patient discontinues Heparin for 1 day and Oral Anticoagulants for 7 days prior to samplingas these drugs may affect test results. Discontinuation should be with prior consent from the treating Physician. Duly filled Coagulation Requisition Form(Form 15) is mandatory.
Test Details

The LUPUS ANTICOAGULANT PANEL, also known as the LAC PANEL test, is a series of laboratory tests used to diagnose lupus anticoagulant (LA), which is an autoimmune disorder that causes abnormal blood clotting. The LAC PANEL test typically includes the following tests:

1. Activated Partial Thromboplastin Time (aPTT): This test measures the time it takes for blood to clot. In the presence of lupus anticoagulant, the aPTT is prolonged.

2. Dilute Russell Viper Venom Time (dRVVT): This test is similar to the aPTT but uses a specific reagent derived from a snake venom. It is more sensitive in detecting lupus anticoagulant.

3. Platelet Neutralization Procedure (PNP): This test is used to confirm the presence of lupus anticoagulant by neutralizing the anticoagulant activity of patient plasma with normal platelets.

4. Hexagonal Phase Phospholipid Neutralization (HexPhos): This test is used to detect lupus anticoagulant by neutralizing the anticoagulant activity of patient plasma with hexagonal phase phospholipids.

5. Confirmation Testing: If the initial screening tests are positive, additional confirmatory tests may be performed, such as mixing studies or specific factor assays.

The LAC PANEL test is ordered when a patient presents with symptoms of abnormal blood clotting, such as deep vein thrombosis or recurrent miscarriages. It is important to note that a positive LAC PANEL test does not necessarily mean the patient has lupus, as lupus anticoagulant can be found in other autoimmune diseases and even in healthy individuals. Therefore, further clinical evaluation is necessary to make a definitive diagnosis.