LIVER KIDNEY MICROSOMAL LKM ANTIBODY IFA Test
Cost: AED 370.0
Symptoms, Diagnosis, and Test Details
The Liver Kidney Microsomal (LKM) Antibody IFA test is a diagnostic test used to detect the presence of antibodies against liver and kidney microsomes in the blood. These antibodies are associated with autoimmune liver diseases such as autoimmune hepatitis type 2 and some cases of drug-induced liver injury.
During the test, a small blood sample is collected from the patient and sent to a laboratory for analysis. In the laboratory, the blood sample is exposed to liver and kidney microsomes that have been fixed to a slide. If the patient’s blood contains LKM antibodies, they will bind to the microsomes on the slide. The test uses indirect immunofluorescence assay (IFA) to detect the binding of antibodies.
After incubation, the slide is washed to remove unbound antibodies, and a fluorescent-labeled secondary antibody is added. This secondary antibody binds to the patient’s antibodies that are bound to the microsomes. When the slide is viewed under a fluorescence microscope, the presence of fluorescent signal indicates the presence of LKM antibodies.
The LKM Antibody IFA test is useful in diagnosing autoimmune liver diseases, particularly autoimmune hepatitis type 2. It can also help differentiate autoimmune liver diseases from other liver conditions. However, it is important to note that a positive test result does not necessarily mean that the patient has liver disease, as LKM antibodies can also be found in healthy individuals or in other autoimmune conditions.
Pre Test Information
No special preparation required.
Test Department: IMMUNOPATHOLOGY
Doctor: Gastroenterologist
Report Delivery
Sample daily by 9 am; Report same day.
Sample Condition
2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen.
Test Type
Disorders of Liver
Test Results and Treatment
The test is typically ordered by a healthcare provider if a patient presents with symptoms of liver disease, such as jaundice, fatigue, or abdominal pain, and there is suspicion of an autoimmune cause. The results of the test, along with other clinical findings and additional laboratory tests, are used to make a diagnosis and determine the appropriate treatment plan.
| Test Name | LIVER KIDNEY MICROSOMAL LKM ANTIBODY IFA Test |
|---|---|
| Components | |
| Price | 370.0 AED |
| Sample Condition | 2 mL (1 mL min.) serum from 1 SST. Ship refrigerated or frozen. |
| Report Delivery | Sample Daily by 9 am;Report Same day |
| Method | Immunofluorescence Assay |
| Test type | Disorders of Liver |
| Doctor | Gastroenterologist |
| Test Department: | IMMUNOPATHOLOGY |
| Pre Test Information | No special preparation required |
| Test Details |
The Liver Kidney Microsomal (LKM) Antibody IFA test is a diagnostic test used to detect the presence of antibodies against liver and kidney microsomes in the blood. These antibodies are associated with autoimmune liver diseases such as autoimmune hepatitis type 2 and some cases of drug-induced liver injury. During the test, a small blood sample is collected from the patient and sent to a laboratory for analysis. In the laboratory, the blood sample is exposed to liver and kidney microsomes that have been fixed to a slide. If the patient’s blood contains LKM antibodies, they will bind to the microsomes on the slide. The test uses indirect immunofluorescence assay (IFA) to detect the binding of antibodies. After incubation, the slide is washed to remove unbound antibodies, and a fluorescent-labeled secondary antibody is added. This secondary antibody binds to the patient’s antibodies that are bound to the microsomes. When the slide is viewed under a fluorescence microscope, the presence of fluorescent signal indicates the presence of LKM antibodies. The LKM Antibody IFA test is useful in diagnosing autoimmune liver diseases, particularly autoimmune hepatitis type 2. It can also help differentiate autoimmune liver diseases from other liver conditions. However, it is important to note that a positive test result does not necessarily mean that the patient has liver disease, as LKM antibodies can also be found in healthy individuals or in other autoimmune conditions. The test is typically ordered by a healthcare provider if a patient presents with symptoms of liver disease, such as jaundice, fatigue, or abdominal pain, and there is suspicion of an autoimmune cause. The results of the test, along with other clinical findings and additional laboratory tests, are used to make a diagnosis and determine the appropriate treatment plan. |
