Sale!

LDLR Gene Hypercholesterolemia Due to LDL-Receptor-Disorder Autosomal Dominant Genetic Test Cost

Original price was: 5,600 د.إ.Current price is: 4,400 د.إ.

-21%

The LDLR gene is crucial in the body’s management of cholesterol levels. It encodes the low-density lipoprotein receptor, which is responsible for removing LDL cholesterol (often referred to as “bad” cholesterol) from the bloodstream. Hypercholesterolemia due to LDL-receptor disorder is a condition where mutations in the LDLR gene impair this process, leading to elevated levels of LDL cholesterol. This condition is typically inherited in an autosomal dominant pattern, meaning a mutation in just one of the two copies of the gene can cause the disorder.

In individuals with a family history of hypercholesterolemia or early heart disease, genetic testing for LDLR gene mutations can be crucial for early diagnosis and management. DNA Labs UAE offers a specific test aimed at identifying mutations in the LDLR gene that are associated with this form of hypercholesterolemia. The test is priced at 4400 AED and involves analyzing the patient’s DNA to detect any genetic alterations that may affect the function of the LDL receptor.

Early identification of individuals carrying LDLR gene mutations allows for timely intervention, which may include lifestyle modifications and pharmacological treatment to manage cholesterol levels and reduce the risk of heart disease. This test is an important tool in the proactive management of inherited hypercholesterolemia, offering a pathway towards personalized medical care for affected individuals and their families.

Home  Sample collection service available

  • 100% accuaret Test Results
  • Ranked as Most trusted Genetic DNA Lab
  • This test is not intended for medical diagnosis or treatment
Guaranteed Safe Checkout

LDLR Gene Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant Genetic Test

Test Name: LDLR Gene Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant Genetic Test

Components: Blood or Extracted DNA or One drop Blood on FTA Card

Price: 4400.0 AED

Report Delivery: 3 to 4 Weeks

Method: NGS Technology

Test Type: Metabolic Disorders

Doctor: General Physician

Test Department: Genetics

Pre Test Information: Clinical History of Patient who is going for LDLR Gene Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant.

Test Details

LDLR gene hypercholesterolemia refers to a genetic disorder caused by mutations in the LDL receptor (LDLR) gene. This disorder is characterized by high levels of low-density lipoprotein cholesterol (LDL-C) in the blood, leading to an increased risk of cardiovascular diseases such as heart attacks and strokes.

The LDLR gene provides instructions for producing the LDL receptor protein, which plays a crucial role in removing LDL-C from the bloodstream. Mutations in this gene can disrupt the function of the LDL receptor, impairing its ability to remove LDL-C effectively. As a result, LDL-C accumulates in the blood, leading to hypercholesterolemia.

LDLR gene hypercholesterolemia is inherited in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the mutated gene from either parent to develop the disorder. Individuals with this condition have a 50% chance of passing the mutation onto each of their children.

NGS (Next-Generation Sequencing) genetic testing is a method used to identify genetic mutations in an individual’s DNA. It involves sequencing the entire exome or specific genes of interest to identify any changes or mutations that may be present. In the case of LDLR gene hypercholesterolemia, NGS genetic testing can identify specific mutations in the LDLR gene that are responsible for the disorder.

NGS genetic testing for LDLR gene hypercholesterolemia can help diagnose affected individuals, determine their risk of developing cardiovascular diseases, and guide treatment decisions. It can also be used for genetic counseling and to identify at-risk family members who may benefit from early intervention and preventive measures.

It is important to note that genetic testing for LDLR gene hypercholesterolemia should be performed by a qualified healthcare professional or genetic counselor, who can interpret the results and provide appropriate recommendations based on the individual’s specific situation.

Test Name LDLR Gene Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant Genetic Test
Components
Price 4400.0 AED
Sample Condition Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery 3 to 4 Weeks
Method NGS Technology
Test type Metabolic Disorders
Doctor General Physician
Test Department: Genetics
Pre Test Information Clinical History of Patient who is going for LDLR Gene Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hypercholesterolemia due to LDL-receptor-disorder autosomal dominant
Test Details

LDLR gene hypercholesterolemia refers to a genetic disorder caused by mutations in the LDL receptor (LDLR) gene. This disorder is characterized by high levels of low-density lipoprotein cholesterol (LDL-C) in the blood, leading to an increased risk of cardiovascular diseases such as heart attacks and strokes.

The LDLR gene provides instructions for producing the LDL receptor protein, which plays a crucial role in removing LDL-C from the bloodstream. Mutations in this gene can disrupt the function of the LDL receptor, impairing its ability to remove LDL-C effectively. As a result, LDL-C accumulates in the blood, leading to hypercholesterolemia.

LDLR gene hypercholesterolemia is inherited in an autosomal dominant manner, meaning that a person only needs to inherit one copy of the mutated gene from either parent to develop the disorder. Individuals with this condition have a 50% chance of passing the mutation onto each of their children.

NGS (Next-Generation Sequencing) genetic testing is a method used to identify genetic mutations in an individual’s DNA. It involves sequencing the entire exome or specific genes of interest to identify any changes or mutations that may be present. In the case of LDLR gene hypercholesterolemia, NGS genetic testing can identify specific mutations in the LDLR gene that are responsible for the disorder.

NGS genetic testing for LDLR gene hypercholesterolemia can help diagnose affected individuals, determine their risk of developing cardiovascular diseases, and guide treatment decisions. It can also be used for genetic counseling and to identify at-risk family members who may benefit from early intervention and preventive measures.

It is important to note that genetic testing for LDLR gene hypercholesterolemia should be performed by a qualified healthcare professional or genetic counselor, who can interpret the results and provide appropriate recommendations based on the individual’s specific situation.