Test Price
2,800 AED✅ Home Collection Available
LAMA3 Gene (Epidermolysis Bullosa, Junctional, Herlitz Type) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced Genetic Test sequences the entire LAMA3 gene to detect pathogenic variants causing Herlitz junctional epidermolysis bullosa (JEB-H), a severe blistering skin disorder presenting at birth. Using Next-Generation Sequencing (NGS) technology, it delivers unparalleled diagnostic precision, enabling early intervention and genetic counseling for affected families in the UAE.
Test Specifications
- Methodology: NGS (Next Generation Sequencing)
- Sample Requirements: Blood (whole blood, extracted DNA, or one drop on FTA Card)
- TAT (Turnaround Time): 3 to 4 Weeks
- Price: 2800 AED (all-inclusive, excluding optional home collection fee)
- Pre-Test Information: Clinical history and a genetic counseling session to draw a pedigree chart of affected family members are mandatory.
| Feature | Our LAMA3 NGS Test | Alternative (Gene Panel / Sanger) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity; full gene coverage including deep intronic regions | 80-90% sensitivity; may miss large deletions/duplications or novel variants |
| Method | Next Generation Sequencing (Illumina platform) | Sanger sequencing or targeted gene panels (limited coverage) |
| Turnaround | 3–4 weeks (cold‑chain stabilized sample) | 5–8 weeks (often without cold‑chain logistics) |
| Regulatory Compliance | ISO 9001:2015, DHA/MOHAP, Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), and Federal Law No. 2 of 2019 | Variable; may lack UAE-specific accreditation |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Geneticist, I emphasize that this genetic test is a cornerstone for confirming Herlitz JEB, yet it must always be interpreted alongside clinical findings. A negative result does not rule out related blistering disorders, and all families should receive thorough genetic counseling. We remain committed to guiding you through every step with empathy and precision.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA ID: 9294403
⚠️ Medication Safety Notice
Do not discontinue any prescribed medication or topical treatment without consulting your doctor. Abrupt cessation of wound care or systemic therapies can precipitate severe blistering and life-threatening infections in epidermolysis bullosa.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients with active systemic infection, recent blood transfusion (within 2 weeks), or those unable to provide informed consent (for minors, legal guardian consent is mandatory per UAE Personal Data Protection Law).
- ER Red Flags: Rapidly spreading bullae with fever, signs of sepsis, respiratory distress (laryngeal involvement), or failure to thrive in a neonate—seek immediate emergency care irrespective of test timing.
- Data Privacy: Your genetic data is protected under Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and processed strictly within DHA‑licensed facilities.
Patient FAQ & Clinical Guidance
1. What does the LAMA3 Genetic Test detect?
Snippet: This test identifies disease‑causing mutations in the LAMA3 gene responsible for Herlitz junctional epidermolysis bullosa with near‑100% accuracy.
It screens the entire coding region and splice sites for point mutations, small insertions/deletions, and copy number variants, enabling definitive molecular diagnosis and differentiation from other epidermolysis bullosa subtypes.
2. Why is genetic counselling required before the test?
Snippet: Mandatory pre‑test genetic counselling maps your family’s inheritance pattern and ensures informed consent, meeting UAE regulatory requirements.
Our certified genetic counsellors construct a detailed pedigree chart, explain possible outcomes, and discuss reproductive options, guaranteeing you understand the test’s benefits, limitations, and potential psychosocial impact.
3. How are samples collected and transported in the UAE?
Snippet: A DHA‑certified phlebotomist collects blood at your home using an ISO‑certified cold‑chain kit, preserving DNA integrity from 8 AM to 11 PM.
The sample is immediately placed in a temperature‑controlled transport container, and all logistics comply with UAE PDPL and ISO 9001:2015 standards. Whole blood, extracted DNA, or a single drop on an FTA card are accepted, offering maximum flexibility.
UAE Regulatory & Data Privacy Adherence
This diagnostic service operates in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – safeguarding your genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – ensuring secure digital health records.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – governing clinical safety and patient consent.
- ISO 9001:2015 Certification: INT/EGQ/2509DA/3139.
All tests are conducted under DHA Facility License No. 1143 at Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE. For emergencies, call 998 or visit the nearest hospital.
Clinical & Logistical Metadata
| Test Name | LAMA3 Gene (Epidermolysis Bullosa, Junctional, Herlitz Type) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type / Matrix | Whole Blood, Extracted DNA, or FTA Card Spot |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | Q81.1 |
| LOINC Code | 81305-1 |
| DHA Facility License & Laboratory Address | License 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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