JAK2 Gene JAK2 Selective Sequencing of Exons 12
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JAK2 Gene JAK2 Selective Sequencing of Exons 12, 14, and 16 Genetic Test Cost

Original price was: 5,600 د.إ.Current price is: 4,400 د.إ.

-21%

The “JAK2 Gene JAK2 Selective Sequencing of Exons 12, 14, and 16 Genetic Test” is a specialized diagnostic procedure available at DNA Labs UAE, aimed at identifying mutations within the Janus kinase 2 (JAK2) gene, specifically within exons 12, 14, and 16. The JAK2 gene plays a crucial role in the signaling pathways that regulate blood cell production in the bone marrow. Mutations in this gene are associated with various myeloproliferative disorders, including polycythemia vera, essential thrombocythemia, and myelofibrosis, which are conditions characterized by the excessive production of blood cells.

This test is particularly significant for patients exhibiting symptoms or laboratory findings suggestive of these hematologic disorders, as it helps in confirming the diagnosis, guiding treatment decisions, and assessing prognosis. The sequencing of exons 12, 14, and 16 is critical as mutations in these regions are commonly implicated in the diseases mentioned.

Performed at the state-of-the-art facilities of DNA Labs UAE, the test cost is set at 4400 AED. The price reflects the advanced technology and expertise required to accurately sequence these specific exons of the JAK2 gene. Upon completion, the test provides clinicians with vital genetic information, enabling personalized patient management strategies based on the genetic makeup of the individual’s condition.

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JAK2 Gene JAK2 selective sequencing of exons 12 14 and 16 Genetic Test

At DNA Labs UAE, we offer the JAK2 Gene JAK2 selective sequencing of exons 12, 14, and 16 Genetic Test at a cost of AED 4400.0. This test is designed to identify mutations or variants in the JAK2 gene that are associated with myeloproliferative neoplasms (MPNs), such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis.

Test Details

The JAK2 gene is responsible for producing a protein called Janus kinase 2, which plays a role in regulating cell growth and division. Mutations in this gene have been linked to various blood disorders, including MPNs. Our selective sequencing test focuses on specific regions of the JAK2 gene, namely exons 12, 14, and 16. Exons are the coding regions of a gene that contain instructions for protein production.

Using next-generation sequencing (NGS) technology, we are able to sequence millions of DNA fragments simultaneously. This allows us to quickly and accurately identify specific mutations or variants in the JAK2 gene that may be responsible for MPNs. NGS is a high-throughput DNA sequencing method that enables us to analyze large portions of the genome, including targeted genes like JAK2.

Test Components and Price

The JAK2 Gene JAK2 selective sequencing of exons 12, 14, and 16 Genetic Test is priced at AED 4400.0. The test can be performed on blood samples, extracted DNA, or even a single drop of blood on an FTA card.

Report Delivery and Method

After the sample is collected, the report will be delivered within 3 to 4 weeks. Our test is conducted using NGS technology, ensuring accurate and reliable results.

Doctor and Test Department

This test is typically recommended by oncologists, as MPNs are a type of cancer. At DNA Labs UAE, our Genetics department specializes in conducting this test and providing comprehensive genetic services.

Pre Test Information

Prior to the test, we recommend a genetic counseling session to gather the clinical history of the patient. This includes information about any family members who may have been affected by MPNs. Drawing a pedigree chart can help identify patterns of inheritance and guide the testing process.

Conclusion

The JAK2 Gene JAK2 selective sequencing of exons 12, 14, and 16 Genetic Test offered by DNA Labs UAE is a valuable tool for diagnosing and managing MPNs. By identifying specific mutations or variants in the JAK2 gene, this test can aid in making accurate diagnoses, determining prognosis, and guiding treatment decisions for individuals suspected of having or already diagnosed with MPNs.

Test Name JAK2 Gene JAK2 selective sequencing of exons 12 14 and 16 Genetic Test
Components
Price 4400.0 AED
Sample Condition Blood or Extracted DNA or One drop Blood on FTA Card
Report Delivery 3 to 4 Weeks
Method NGS Technology
Test type Cancer
Doctor Oncologist
Test Department: Genetics
Pre Test Information Clinical History of Patient who is going for JAK2 Gene JAK2, selective sequencing of exons 12, 14 and 16 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with JAK2 Gene JAK2, selective sequencing of exons 12, 14 and 16 NGS Genetic DNA Test gene JAK2
Test Details

The JAK2 gene is a protein-coding gene that provides instructions for making a protein called Janus kinase 2. This protein is involved in signaling pathways that regulate cell growth and division. Mutations in the JAK2 gene have been associated with several blood disorders, including myeloproliferative neoplasms (MPNs) such as polycythemia vera, essential thrombocythemia, and primary myelofibrosis.

Selective sequencing of exons 12, 14, and 16 of the JAK2 gene is a type of genetic test that focuses on specific regions of the gene. Exons are the coding regions of a gene that contain the instructions for making the protein, while introns are non-coding regions. By sequencing only specific exons, this test can identify mutations or variants that are known to be associated with MPNs.

Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that allows for the simultaneous sequencing of millions of DNA fragments. This technology enables researchers to quickly and accurately sequence large portions of the genome, including specific genes like JAK2.

The selective sequencing of exons 12, 14, and 16 of the JAK2 gene using NGS can help identify specific mutations or variants that may be responsible for MPNs. This information can be useful for diagnosis, prognosis, and treatment decisions for individuals suspected of having or already diagnosed with MPNs.

SKU: TEST-4499 Category:

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