JAG2 Gene Craniofacial and Neuro-developmental Abnormalities
At DNA Labs UAE, we offer a comprehensive genetic test for JAG2 gene craniofacial and neuro-developmental abnormalities. This test can help diagnose and understand the underlying cause of these abnormalities, allowing for appropriate treatment and management strategies.
Test Details
The JAG2 gene is responsible for producing a protein called jagged-2, which plays a crucial role in the Notch signaling pathway. This pathway is essential for the development of various tissues and organs in the body. Mutations or alterations in the JAG2 gene can lead to craniofacial and neuro-developmental abnormalities.
To diagnose JAG2-related craniofacial and neuro-developmental abnormalities, we use a genetic test called next-generation sequencing (NGS). NGS is a high-throughput method that allows for the rapid sequencing of large amounts of DNA. It can detect mutations or alterations in the JAG2 gene that may be responsible for the observed abnormalities.
During the test, we obtain a DNA sample from the individual being tested. This can be done through a blood sample, saliva sample, or one drop of blood on an FTA card. The DNA sample is then sequenced using NGS technology to identify any changes or mutations in the JAG2 gene.
Test Components and Price
The cost of the JAG2 gene craniofacial and neuro-developmental abnormalities genetic test is AED 4400.0. The test includes:
- NGS Technology
- Dysmorphology Test Type
- Genetics Test Department
Sample Condition and Report Delivery
We accept blood samples, extracted DNA, or one drop of blood on an FTA card as sample conditions for the test. The report will be delivered within 3 to 4 weeks after the sample is received.
Pre Test Information
Before undergoing the JAG2 gene craniofacial and neuro-developmental abnormalities genetic test, it is important to provide the clinical history of the patient. Additionally, a genetic counseling session will be conducted to draw a pedigree chart of family members affected by JAG2 gene craniofacial and neuro-developmental abnormalities.
Doctor and Test Department
The JAG2 gene craniofacial and neuro-developmental abnormalities genetic test is conducted under the supervision of a pediatrician. The test is performed in our Genetics Test Department.
Please note that genetic testing, including NGS, should only be performed and interpreted by qualified healthcare professionals, such as geneticists or genetic counselors. These professionals can provide appropriate counseling and guidance based on the test results.
| Test Name | JAG2 Gene Craniofacial and neuro-developmental abnormalities JAG2 related Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Dysmorphology |
| Doctor | Pediatrics |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for JAG2 Gene Craniofacial and neuro-developmental abnormalities, JAG2 related NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with JAG2 Gene Craniofacial and neuro-developmental abnormalities, JAG2 related NGS Genetic DNA Test gene JAG2 |
| Test Details |
The JAG2 gene is a gene that provides instructions for making a protein called jagged-2. This protein is involved in a signaling pathway known as the Notch signaling pathway, which plays a critical role in the development of various tissues and organs in the body. Mutations or alterations in the JAG2 gene can lead to craniofacial and neuro-developmental abnormalities. These abnormalities can vary widely in their severity and can affect different parts of the body, including the head, face, brain, and nervous system. To diagnose JAG2-related craniofacial and neuro-developmental abnormalities, a genetic test called next-generation sequencing (NGS) can be performed. NGS is a high-throughput method that allows for the rapid sequencing of large amounts of DNA. It can detect mutations or alterations in the JAG2 gene that may be responsible for the observed abnormalities. NGS genetic testing involves obtaining a DNA sample, usually through a blood sample or saliva sample, from the individual being tested. The DNA is then sequenced using NGS technology to identify any changes or mutations in the JAG2 gene. The results of the NGS genetic test can help healthcare professionals confirm a diagnosis of JAG2-related craniofacial and neuro-developmental abnormalities. This information can be crucial for understanding the underlying cause of the condition, predicting its progression, and informing appropriate treatment and management strategies. It is important to note that genetic testing, including NGS, should be performed and interpreted by qualified healthcare professionals, such as geneticists or genetic counselors, who can provide appropriate counseling and guidance based on the test results. |
