ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test
At DNA Labs UAE, we offer the ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test. This test helps in diagnosing leukocyte adhesion deficiency (LAD), specifically LAD type 1, which is a rare autosomal recessive disorder.
Test Details
The ITGB2 gene is responsible for encoding the integrin beta-2 subunit, a protein involved in leukocyte adhesion and migration. Mutations in this gene can lead to LAD, causing impaired leukocyte adhesion to blood vessel walls and defective migration to sites of infection or inflammation. As a result, individuals with LAD experience recurrent severe bacterial infections and impaired wound healing.
Our ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test utilizes Next-Generation Sequencing (NGS) technology. This advanced method allows for the simultaneous analysis of multiple genes, including the ITGB2 gene, to identify genetic variations or mutations associated with LAD. By providing a comprehensive analysis, this test offers a more accurate diagnosis.
Test Components and Price
The ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test is priced at AED 4400.0. The test can be performed on a blood or extracted DNA sample, or even just one drop of blood on an FTA card.
Report Delivery
After the sample is collected, the report will be delivered within 3 to 4 weeks.
Test Type and Department
The ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test falls under the category of Metabolic Disorders. It is conducted in our Genetics department.
Referring Doctor
Our ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test can be requested by a General Physician.
Pre Test Information
Prior to the test, it is essential to provide the clinical history of the patient who is going for the ITGB2 Gene Leukocyte Adhesion Deficiency NGS Genetic DNA Test. Additionally, a genetic counseling session is recommended to draw a pedigree chart of family members affected with Leukocyte adhesion deficiency.
Benefits of the ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test
The results of the ITGB2 Gene Leukocyte Adhesion Deficiency Genetic Test can help guide treatment decisions, provide information on disease prognosis, and assist in genetic counseling for affected individuals and their families.
| Test Name | ITGB2 Gene Leukocyte adhesion deficiency Genetic Test |
|---|---|
| Components | |
| Price | 4400.0 AED |
| Sample Condition | Blood or Extracted DNA or One drop Blood on FTA Card |
| Report Delivery | 3 to 4 Weeks |
| Method | NGS Technology |
| Test type | Metabolic Disorders |
| Doctor | General Physician |
| Test Department: | Genetics |
| Pre Test Information | Clinical History of Patient who is going for ITGB2 Gene Leukocyte adhesion deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Leukocyte adhesion deficiency |
| Test Details |
The ITGB2 gene is responsible for encoding the integrin beta-2 subunit, which is a protein involved in leukocyte adhesion and migration. Mutations in the ITGB2 gene can lead to a condition called leukocyte adhesion deficiency (LAD), specifically LAD type 1. LAD is a rare autosomal recessive disorder characterized by impaired leukocyte adhesion to the blood vessel walls and subsequent defective migration to sites of infection or inflammation. This results in recurrent severe bacterial infections and impaired wound healing. NGS (Next-Generation Sequencing) genetic testing is a method used to analyze multiple genes simultaneously to identify genetic variations or mutations associated with a particular condition, such as LAD. This type of testing allows for a comprehensive analysis of the ITGB2 gene and other relevant genes, providing a more accurate diagnosis. NGS genetic testing for LAD can be performed on a blood or saliva sample, and the results can help guide treatment decisions, provide information on disease prognosis, and assist in genetic counseling for affected individuals and their families. |
