Immunosuppressant Drug Profile 4 Test sale cost 1920 AED
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Immunosuppressant Drug Profile 4 Test

Original price was: 2,130 د.إ.Current price is: 1,920 د.إ.

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The “Immunosuppressant Drug Profile 4 Test” is a specialized medical examination offered by DNA Labs UAE, designed to measure the levels of certain immunosuppressant drugs in the bloodstream. This test is particularly crucial for individuals who have undergone organ transplantation or those being treated for autoimmune diseases, as it helps in ensuring that the dosage of immunosuppressant medications is optimal. By monitoring the concentration of these drugs, healthcare providers can adjust dosages to prevent organ rejection while minimizing the risk of drug toxicity.

The test covers a specific panel of immunosuppressant drugs, although the exact drugs included in “Profile 4” are not specified here. These drugs typically include agents like cyclosporine, tacrolimus, sirolimus, and mycophenolate mofetil, among others, which are commonly used to suppress the immune system in various clinical scenarios.

Administered at DNA Labs UAE, a facility known for its state-of-the-art diagnostic services, the test ensures accuracy and reliability in results. The cost of the “Immunosuppressant Drug Profile 4 Test” is set at 1920 AED. Given the critical nature of immunosuppressant therapy in transplant and autoimmune disease management, this test plays a vital role in patient care, ensuring that therapeutic levels are maintained for efficacy while reducing the risk of adverse effects.

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IMMUNOSUPPRESSANT DRUG PROFILE 4 Test

Test Name: IMMUNOSUPPRESSANT DRUG PROFILE 4 Test

Components: Tacrolimus, Everolimus

Price: 1920.0 AED

Sample Condition: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated. Ideal sampling time: Just before the next dose (Trough levels). Provide date & time of sampling, dose taken & time of dosing.

Report Delivery: Sample Daily by 5 pm; Report Same day

Method: LC-MS/MS

Test type: Therapeutic Drug Monitoring

Doctor: Gastroenterologist, Nephrologist

Test Department: GENETIC

Pre Test Information: Provide date & time of sampling, dose taken & time of dosing.

Test Details

Name: Tacrolimus

Class: Immunosuppressant

Mechanism of Action: Tacrolimus inhibits the activation of T-lymphocytes by binding to and inhibiting the enzyme calcineurin. This prevents the production of cytokines and the activation of T-cells, leading to immunosuppression.

Indications: Tacrolimus is primarily used for the prevention of organ rejection in patients who have undergone organ transplantation, including liver, kidney, and heart transplants. It may also be used in the treatment of certain autoimmune diseases, such as rheumatoid arthritis and psoriasis.

Dosage and Administration: Tacrolimus is available in oral capsule and injection forms. The dosage may vary depending on the patient’s age, weight, and specific condition. It is typically administered twice daily, with or without food. The initial dose is usually higher and is gradually reduced over time to maintain therapeutic levels.

Adverse Effects: Common side effects of tacrolimus include tremor, headache, diarrhea, nausea, high blood pressure, and increased risk of infections. Long-term use may also increase the risk of developing certain types of cancer, such as lymphoma and skin cancer. It is important for patients taking tacrolimus to undergo regular monitoring of blood pressure, kidney function, and blood cell counts.

Contraindications: Tacrolimus is contraindicated in patients with hypersensitivity to the drug or its components. It should also be used with caution in patients with liver or kidney dysfunction, as it is primarily metabolized in the liver and excreted by the kidneys.

Drug Interactions: Tacrolimus may interact with several medications, including certain antibiotics, antifungals, and antivirals. It may also interact with drugs that affect the liver enzymes responsible for metabolizing tacrolimus, such as grapefruit juice. These interactions can affect the blood levels of tacrolimus and may require dose adjustments.

Monitoring: Regular monitoring of tacrolimus blood levels is essential to ensure therapeutic efficacy and prevent toxicity. The target blood levels may vary depending on the indication and the time since transplantation. Additional monitoring of kidney function, blood pressure, and blood cell counts is also recommended.

Pregnancy and Lactation: Tacrolimus should be used with caution during pregnancy, as it may cause harm to the fetus. It is not recommended for use during breastfeeding, as it may pass into breast milk and harm the infant.

Overall, tacrolimus is an effective immunosuppressant drug used in organ transplantation and certain autoimmune diseases. However, it carries the risk of various side effects and requires close monitoring to ensure optimal therapeutic outcomes.

Test Name IMMUNOSUPPRESSANT DRUG PROFILE 4 Test
Components *Tacrolimus*Everolimus
Price 1920.0 AED
Sample Condition 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated. Ideal sampling time: Just before the next dose (Trough levels). Provide date & time of sampling, dose taken & time of dosing.
Report Delivery Sample Daily by 5 pm; Report Same day
Method LC-MS/MS
Test type Therapeutic Drug Monitoring
Doctor Gastroenterologist, Nephrologist
Test Department: GENETIC
Pre Test Information Provide date & time of sampling, dose taken & time of dosing.
Test Details

Name: Tacrolimus

Class: Immunosuppressant

Mechanism of Action: Tacrolimus inhibits the activation of T-lymphocytes by binding to and inhibiting the enzyme calcineurin. This prevents the production of cytokines and the activation of T-cells, leading to immunosuppression.

Indications: Tacrolimus is primarily used for the prevention of organ rejection in patients who have undergone organ transplantation, including liver, kidney, and heart transplants. It may also be used in the treatment of certain autoimmune diseases, such as rheumatoid arthritis and psoriasis.

Dosage and Administration: Tacrolimus is available in oral capsule and injection forms. The dosage may vary depending on the patient’s age, weight, and specific condition. It is typically administered twice daily, with or without food. The initial dose is usually higher and is gradually reduced over time to maintain therapeutic levels.

Adverse Effects: Common side effects of tacrolimus include tremor, headache, diarrhea, nausea, high blood pressure, and increased risk of infections. Long-term use may also increase the risk of developing certain types of cancer, such as lymphoma and skin cancer. It is important for patients taking tacrolimus to undergo regular monitoring of blood pressure, kidney function, and blood cell counts.

Contraindications: Tacrolimus is contraindicated in patients with hypersensitivity to the drug or its components. It should also be used with caution in patients with liver or kidney dysfunction, as it is primarily metabolized in the liver and excreted by the kidneys.

Drug Interactions: Tacrolimus may interact with several medications, including certain antibiotics, antifungals, and antivirals. It may also interact with drugs that affect the liver enzymes responsible for metabolizing tacrolimus, such as grapefruit juice. These interactions can affect the blood levels of tacrolimus and may require dose adjustments.

Monitoring: Regular monitoring of tacrolimus blood levels is essential to ensure therapeutic efficacy and prevent toxicity. The target blood levels may vary depending on the indication and the time since transplantation. Additional monitoring of kidney function, blood pressure, and blood cell counts is also recommended.

Pregnancy and Lactation: Tacrolimus should be used with caution during pregnancy, as it may cause harm to the fetus. It is not recommended for use during breastfeeding, as it may pass into breast milk and harm the infant.

Overall, tacrolimus is an effective immunosuppressant drug used in organ transplantation and certain autoimmune diseases. However, it carries the risk of various side effects and requires close monitoring to ensure optimal therapeutic outcomes.

SKU: TEST-5089 Category:

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