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Immunosuppressant Drug Profile 1 Test Cost

Original price was: 2,130 د.إ.Current price is: 1,920 د.إ.

-10%

The “Immunosuppressant Drug Profile 1 Test” is a specialized diagnostic examination offered at DNA Labs UAE, designed to monitor and measure the levels of certain immunosuppressive drugs in the bloodstream. This test is particularly crucial for patients who have undergone organ transplants or those being treated for autoimmune diseases, as it helps in ensuring that the dosage of immunosuppressant medication is optimal. By maintaining the right balance, the test aids in preventing organ rejection while minimizing the risk of drug toxicity.

The cost of the test is 1920 AED, reflecting the intricate nature of the analysis and the sophisticated technology utilized to achieve accurate results. Conducted in the state-of-the-art facilities of DNA Labs UAE, the test ensures reliability and precision, providing essential information for the effective management of immunosuppressive therapy. This test is a key component in the personalized treatment plans for patients requiring immunosuppression, enabling healthcare providers to make informed decisions regarding dosage adjustments and overall treatment strategies.

Description

IMMUNOSUPPRESSANT DRUG PROFILE 1 Test

Test Cost: AED 1920.0

Test Components:

Tacrolimus
Sirolimus

Sample Condition:

3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated. Ideal sampling time: Just before the next dose (Trough levels). Provide date & time of sampling, dose taken & time of dosing.

Report Delivery:

Sample Daily by 5 pm; Report Same day

Method:

LC-MS/MS

Test Type:

Therapeutic Drug Monitoring

Doctor:

Gastroenterologist, Nephrologist

Test Department:

GENETIC

Pre Test Information:

Provide date & time of sampling, dose taken & time of dosing.

Test Details:

Drug Name: Methotrexate

Drug Class: Immunosuppressant, Antimetabolite

Mechanism of Action: Methotrexate inhibits the enzyme dihydrofolate reductase, which is necessary for the synthesis of DNA, RNA, and proteins. By interfering with these processes, methotrexate suppresses the proliferation of immune cells, particularly T cells, leading to immunosuppression.

Indications: Methotrexate is commonly used in the treatment of various autoimmune diseases, including rheumatoid arthritis, psoriasis, and Crohn’s disease. It can also be used in the management of certain types of cancer, such as leukemia and lymphoma.

Dosage and Administration: Methotrexate can be taken orally, as a tablet or liquid, or administered as an injection. The dosage and frequency of administration depend on the specific condition being treated and individual patient factors. It is important to follow the prescribed dosage and administration instructions closely.

Contraindications and Precautions: Methotrexate is contraindicated in individuals with known hypersensitivity to the drug, severe renal impairment, severe liver impairment, or significant bone marrow suppression. It should be used with caution in patients with pre-existing liver disease, renal impairment, or compromised immune function. Methotrexate is also contraindicated in pregnant women, as it can cause severe birth defects.

Adverse Effects: Common side effects of methotrexate include nausea, vomiting, diarrhea, mouth sores, hair loss, and fatigue. More serious adverse effects can occur, such as liver toxicity, bone marrow suppression, and lung inflammation. Regular monitoring of liver function and blood cell counts is essential during treatment.

Drug Interactions: Methotrexate can interact with various medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), penicillins, sulfonamides, and certain antibiotics. These interactions can increase the risk of methotrexate toxicity. It is important to inform the healthcare provider about all medications being taken, including over-the-counter drugs and supplements.

Warnings and Precautions: Methotrexate can have toxic effects on multiple organs, particularly the liver, kidneys, and bone marrow. Regular monitoring of liver function tests, complete blood counts, and renal function is necessary to detect any potential complications. Methotrexate should not be used during pregnancy or breastfeeding due to the risk of birth defects and harm to the infant.

Overall, methotrexate is an effective immunosuppressant drug used in the treatment of autoimmune diseases and certain types of cancer. However, close monitoring and adherence to dosage instructions are crucial to minimize the risk of adverse effects and drug interactions.

Test Name	IMMUNOSUPPRESSANT DRUG PROFILE 1 Test
Components	TacrolimusSirolimus
Price	1920.0 AED
Sample Condition	3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube. Ship refrigerated. Ideal sampling time: Just before the next dose (Trough levels). Provide date & time of sampling, dose taken & time of dosing.
Report Delivery	Sample Daily by 5 pm; Report Same day
Method	LC-MS/MS
Test type	Therapeutic Drug Monitoring
Doctor	Gastroenterologist, Nephrologist
Test Department:	GENETIC
Pre Test Information	Provide date & time of sampling, dose taken & time of dosing.
Test Details	Drug Name: Methotrexate Drug Class: Immunosuppressant, Antimetabolite Mechanism of Action: Methotrexate inhibits the enzyme dihydrofolate reductase, which is necessary for the synthesis of DNA, RNA, and proteins. By interfering with these processes, methotrexate suppresses the proliferation of immune cells, particularly T cells, leading to immunosuppression. Indications: Methotrexate is commonly used in the treatment of various autoimmune diseases, including rheumatoid arthritis, psoriasis, and Crohn’s disease. It can also be used in the management of certain types of cancer, such as leukemia and lymphoma. Dosage and Administration: Methotrexate can be taken orally, as a tablet or liquid, or administered as an injection. The dosage and frequency of administration depend on the specific condition being treated and individual patient factors. It is important to follow the prescribed dosage and administration instructions closely. Contraindications and Precautions: Methotrexate is contraindicated in individuals with known hypersensitivity to the drug, severe renal impairment, severe liver impairment, or significant bone marrow suppression. It should be used with caution in patients with pre-existing liver disease, renal impairment, or compromised immune function. Methotrexate is also contraindicated in pregnant women, as it can cause severe birth defects. Adverse Effects: Common side effects of methotrexate include nausea, vomiting, diarrhea, mouth sores, hair loss, and fatigue. More serious adverse effects can occur, such as liver toxicity, bone marrow suppression, and lung inflammation. Regular monitoring of liver function and blood cell counts is essential during treatment. Drug Interactions: Methotrexate can interact with various medications, including nonsteroidal anti-inflammatory drugs (NSAIDs), penicillins, sulfonamides, and certain antibiotics. These interactions can increase the risk of methotrexate toxicity. It is important to inform the healthcare provider about all medications being taken, including over-the-counter drugs and supplements. Warnings and Precautions: Methotrexate can have toxic effects on multiple organs, particularly the liver, kidneys, and bone marrow. Regular monitoring of liver function tests, complete blood counts, and renal function is necessary to detect any potential complications. Methotrexate should not be used during pregnancy or breastfeeding due to the risk of birth defects and harm to the infant. Overall, methotrexate is an effective immunosuppressant drug used in the treatment of autoimmune diseases and certain types of cancer. However, close monitoring and adherence to dosage instructions are crucial to minimize the risk of adverse effects and drug interactions.

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