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Immunophenotyping by Flow Cytometry TdT Test Cost

Original price was: 530 د.إ.Current price is: 480 د.إ.

-9%

Immunophenotyping by Flow Cytometry TdT (Terminal deoxynucleotidyl transferase) Test is a sophisticated diagnostic procedure used to identify and classify cells based on the presence of specific surface markers or proteins. This test is particularly significant in the diagnosis and classification of leukemia and lymphomas, where it aids in determining the lineage and developmental stage of malignant cells. TdT is an enzyme that is highly expressed in the early stages of T and B lymphocyte development, making its detection crucial for diagnosing acute lymphoblastic leukemia (ALL) and some types of lymphoblastic lymphoma.

Flow cytometry is the technology underpinning this test, enabling the rapid analysis of multiple characteristics of single cells as they flow in a fluid stream through a beam of light. The presence or absence of TdT, along with other cell markers, helps in the accurate classification of hematological malignancies, which is vital for determining the most effective treatment strategy.

In the United Arab Emirates, this specific test is available at DNA Labs UAE, a leading diagnostic center known for its state-of-the-art facilities and expert team of pathologists and technicians. The cost of the Immunophenotyping by Flow Cytometry TdT Test at DNA Labs UAE is 480 AED. This test is a critical tool in the arsenal of diagnostic procedures for hematologic cancers, offering patients a targeted approach to treatment and management of their condition.

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IMMUNOPHENOTYPING BY FLOW CYTOMETRY TdT Test

Test Details

The TdT (Terminal deoxynucleotidyl transferase) test is a flow cytometry-based immunophenotyping assay used to detect the presence of TdT enzyme in cells. TdT is an enzyme that adds nucleotides to the ends of DNA strands during V(D)J recombination, a process that occurs during the development of T and B lymphocytes.

The TdT test is commonly used in the diagnosis and classification of lymphoid malignancies, such as acute lymphoblastic leukemia (ALL). In normal lymphoid cells, TdT expression is restricted to early precursor cells, while mature lymphocytes do not express TdT. However, in certain lymphoid malignancies, TdT can be aberrantly expressed, providing important diagnostic information.

The TdT test involves staining cells with fluorescently labeled antibodies specific for TdT. The cells are then analyzed using flow cytometry, a technique that allows for the simultaneous analysis of multiple parameters on individual cells. By measuring the fluorescence intensity of the TdT antibody, flow cytometry can determine the presence or absence of TdT in the analyzed cells.

The TdT test is typically performed on bone marrow or peripheral blood samples. It can help distinguish between different types of lymphoid malignancies and can be used in combination with other immunophenotyping markers to provide a more comprehensive characterization of the disease.

Overall, the TdT test is a valuable tool in the diagnosis and classification of lymphoid malignancies, providing important information about the stage and type of the disease.

Test Name

IMMUNOPHENOTYPING BY FLOW CYTOMETRY TdT Test

Components

Price: 480.0 AED

Sample Condition

  • 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube
  • 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube
  • Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE.
  • Specify time, date, and clinical details on the test request form.

Report Delivery

Sample: Daily by 9 am

Report: Same day

Method

Flow Cytometry

Test Type

Cancer

Doctor

Oncologist, Hematologist

Test Department

FLOW CYTOMETRY

Pre Test Information

Give brief clinical history.

Test Name IMMUNOPHENOTYPING BY FLOW CYTOMETRY TdT Test
Components
Price 480.0 AED
Sample Condition 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tubeAND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube. Ship immediately at 18\u0192??22?\u00f8C. DO NOT REFRIGERATE OR FREEZE. Specify time, date and clinical details on test request form.
Report Delivery Sample Daily by 9 am; Report Same day
Method Flow Cytometry
Test type Cancer
Doctor Oncologist, Hematologist
Test Department: FLOW CYTOMETRY
Pre Test Information Give brief clinical history.
Test Details

The TdT (Terminal deoxynucleotidyl transferase) test is a flow cytometry-based immunophenotyping assay used to detect the presence of TdT enzyme in cells. TdT is an enzyme that adds nucleotides to the ends of DNA strands during V(D)J recombination, a process that occurs during the development of T and B lymphocytes.

The TdT test is commonly used in the diagnosis and classification of lymphoid malignancies, such as acute lymphoblastic leukemia (ALL). In normal lymphoid cells, TdT expression is restricted to early precursor cells, while mature lymphocytes do not express TdT. However, in certain lymphoid malignancies, TdT can be aberrantly expressed, providing important diagnostic information.

The TdT test involves staining cells with fluorescently labeled antibodies specific for TdT. The cells are then analyzed using flow cytometry, a technique that allows for the simultaneous analysis of multiple parameters on individual cells. By measuring the fluorescence intensity of the TdT antibody, flow cytometry can determine the presence or absence of TdT in the analyzed cells.

The TdT test is typically performed on bone marrow or peripheral blood samples. It can help distinguish between different types of lymphoid malignancies and can be used in combination with other immunophenotyping markers to provide a more comprehensive characterization of the disease.

Overall, the TdT test is a valuable tool in the diagnosis and classification of lymphoid malignancies, providing important information about the stage and type of the disease.