IMMUNOPHENOTYPING BY FLOW CYTOMETRY CD64 Test
Test Name: IMMUNOPHENOTYPING BY FLOW CYTOMETRY CD64 Test
Components: CD64 Test
Price: 480.0 AED
Sample Condition: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube and 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube. Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Specify time, date, and clinical details on the test request form.
Report Delivery: Sample Daily by 9 am; Report Same day
Method: Flow Cytometry
Test type: Cancer
Doctor: Hematologist, Oncologist
Test Department: FLOW CYTOMETRY
Pre Test Information: Give brief clinical history.
Test Details:
The CD64 test is a flow cytometry-based immunophenotyping assay used to measure the expression of CD64 on the surface of immune cells, particularly monocytes and macrophages. CD64, also known as FcRI, is a high-affinity receptor for the Fc region of immunoglobulin G (IgG). It is expressed on the surface of monocytes, macrophages, and to a lesser extent, neutrophils. CD64 plays a crucial role in immune responses by mediating the phagocytosis of opsonized pathogens and immune complexes.
The CD64 test is commonly used in clinical and research settings to assess the activation status of monocytes and macrophages. It can be used to identify and quantify the proportion of cells expressing CD64, as well as to determine the intensity of CD64 expression on these cells. Changes in CD64 expression levels can provide valuable insights into immune system dysregulation, such as in autoimmune diseases, infections, and certain malignancies.
To perform the CD64 test, peripheral blood or other biological samples are collected from the patient and treated with specific antibodies labeled with fluorochromes that bind to CD64. The samples are then analyzed using flow cytometry, which allows for the simultaneous measurement of multiple parameters, such as cell size, granularity, and fluorescence intensity. By gating on the monocyte or macrophage population, the expression levels of CD64 can be determined.
The CD64 test can provide valuable information about the activation and function of monocytes and macrophages in various disease states. It can aid in the diagnosis, prognosis, and monitoring of diseases, as well as in the assessment of therapeutic interventions targeting these immune cells.
| Test Name | IMMUNOPHENOTYPING BY FLOW CYTOMETRY CD64 Test |
|---|---|
| Components | |
| Price | 480.0 AED |
| Sample Condition | 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tubeAND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube. Ship immediately at 18\u0192??22?\u00f8C. DO NOT REFRIGERATE OR FREEZE. Specify time, date and clinical details on test request form. |
| Report Delivery | Sample Daily by 9 am; Report Same day |
| Method | Flow Cytometry |
| Test type | Cancer |
| Doctor | Hematologist, Oncologist |
| Test Department: | FLOW CYTOMETRY |
| Pre Test Information | Give brief clinical history. |
| Test Details |
The CD64 test is a flow cytometry-based immunophenotyping assay used to measure the expression of CD64 on the surface of immune cells, particularly monocytes and macrophages. CD64, also known as FcRI, is a high-affinity receptor for the Fc region of immunoglobulin G (IgG). It is expressed on the surface of monocytes, macrophages, and to a lesser extent, neutrophils. CD64 plays a crucial role in immune responses by mediating the phagocytosis of opsonized pathogens and immune complexes. The CD64 test is commonly used in clinical and research settings to assess the activation status of monocytes and macrophages. It can be used to identify and quantify the proportion of cells expressing CD64, as well as to determine the intensity of CD64 expression on these cells. Changes in CD64 expression levels can provide valuable insights into immune system dysregulation, such as in autoimmune diseases, infections, and certain malignancies. To perform the CD64 test, peripheral blood or other biological samples are collected from the patient and treated with specific antibodies labeled with fluorochromes that bind to CD64. The samples are then analyzed using flow cytometry, which allows for the simultaneous measurement of multiple parameters, such as cell size, granularity, and fluorescence intensity. By gating on the monocyte or macrophage population, the expression levels of CD64 can be determined. The CD64 test can provide valuable information about the activation and function of monocytes and macrophages in various disease states. It can aid in the diagnosis, prognosis, and monitoring of diseases, as well as in the assessment of therapeutic interventions targeting these immune cells. |
