IMMUNOHISTOCHEMISTRY PLA2R Test
Components: Price – 470.0 AED
Sample Condition: Submit tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Report Delivery: Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex: 7 days
Method: Immunohistochemistry
Test type: Disorders of Kidney
Doctor: Nephrologist, Pathologist
Test Department: HISTOLOGY
Pre Test Information: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Test Details
The PLA2R test is an immunohistochemistry (IHC) test used to detect the presence of phospholipase A2 receptor (PLA2R) in kidney tissue. This test is primarily used to aid in the diagnosis of primary membranous nephropathy (PMN), a kidney disease characterized by the deposition of immune complexes in the glomerular basement membrane.
During the PLA2R test, a small sample of kidney tissue is collected through a biopsy procedure. The tissue sample is then processed and embedded in paraffin wax to create thin sections. These sections are mounted on glass slides and treated with specific antibodies that bind to the PLA2R protein if present. The antibodies used in the PLA2R test are typically labeled with a fluorescent or enzymatic marker, allowing for the visualization of the protein under a microscope.
If the tissue sample shows positive staining for PLA2R, it indicates the presence of PLA2R in the kidney tissue, suggesting a diagnosis of PMN. The PLA2R test is considered a highly specific and sensitive diagnostic tool for PMN. It helps differentiate PMN from secondary causes of membranous nephropathy, such as lupus nephritis or drug-induced nephropathy.
Additionally, monitoring PLA2R levels over time can be useful in assessing disease activity and response to treatment in patients with PMN.
| Test Name | IMMUNOHISTOCHEMISTRY PLA2R Test |
|---|---|
| Components | |
| Price | 470.0 AED |
| Sample Condition | Submit tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Report Delivery | Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days |
| Method | Immunohistochemistry |
| Test type | Disorders of Kidney |
| Doctor | Nephrologist, Pathologist |
| Test Department: | HISTOLOGY |
| Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test Details | The PLA2R test is an immunohistochemistry (IHC) test used to detect the presence of phospholipase A2 receptor (PLA2R) in kidney tissue. This test is primarily used to aid in the diagnosis of primary membranous nephropathy (PMN), a kidney disease characterized by the deposition of immune complexes in the glomerular basement membrane. During the PLA2R test, a small sample of kidney tissue is collected through a biopsy procedure. The tissue sample is then processed and embedded in paraffin wax to create thin sections. These sections are mounted on glass slides and treated with specific antibodies that bind to the PLA2R protein if present. The antibodies used in the PLA2R test are typically labeled with a fluorescent or enzymatic marker, allowing for the visualization of the protein under a microscope. If the tissue sample shows positive staining for PLA2R, it indicates the presence of PLA2R in the kidney tissue, suggesting a diagnosis of PMN. The PLA2R test is considered a highly specific and sensitive diagnostic tool for PMN. It helps differentiate PMN from secondary causes of membranous nephropathy, such as lupus nephritis or drug-induced nephropathy. Additionally, monitoring PLA2R levels over time can be useful in assessing disease activity and response to treatment in patients with PMN. |
