IMMUNOHISTOCHEMISTRY MUC4 Test – DNA Labs UAE
Test Details
IMMUNOHISTOCHEMISTRY MUC4 Test is a technique used to detect specific proteins in tissue samples using antibodies. MUC4 is a protein commonly expressed in various tissues, including the respiratory and digestive tracts.
The MUC4 test involves the use of specific antibodies that bind to the MUC4 protein in tissue samples. These antibodies are usually labeled with a colored or fluorescent marker, allowing for visualization of the protein under a microscope.
This test is often used in diagnostic pathology to identify the presence and distribution of MUC4 protein in tissue samples. It can help in the diagnosis and classification of certain diseases, such as pancreatic cancer and lung adenocarcinoma.
Test Procedure
- Tissue sample preparation: The tissue sample is collected from a patient and processed to create thin sections that can be mounted on glass slides.
- Antigen retrieval: The tissue sections are treated to retrieve the MUC4 protein antigen, which may be masked or damaged during the tissue processing.
- Blocking: The tissue sections are treated with a blocking solution to prevent non-specific binding of antibodies.
- Primary antibody incubation: The tissue sections are incubated with the primary antibody specific to the MUC4 protein. This antibody binds to the MUC4 protein if it is present in the tissue sample.
- Secondary antibody incubation: The tissue sections are then incubated with a secondary antibody that is labeled with a colored or fluorescent marker. This secondary antibody binds to the primary antibody, allowing for visualization of the MUC4 protein.
- Visualization: The tissue sections are examined under a microscope to visualize the presence and distribution of the MUC4 protein. The colored or fluorescent marker indicates the location of the MUC4 protein in the tissue sample.
Test Cost
The cost of the IMMUNOHISTOCHEMISTRY MUC4 Test is 520.0 AED.
Sample Condition
To perform the test, submit tumor tissue in 10% Formal-saline or Formalin fixed paraffin embedded block. The sample should be shipped at room temperature. Additionally, provide a copy of the Histopathology report, site of biopsy, and clinical history.
Report Delivery
The test results will be delivered within 10 days.
Test Type
The IMMUNOHISTOCHEMISTRY MUC4 Test is specifically used for cancer detection.
Doctor
This test can be ordered by an Oncologist or a Pathologist.
Test Department
The IMMUNOHISTOCHEMISTRY MUC4 Test is performed in the Histology department of DNA Labs UAE.
Pre Test Information
Prior to the test, provide a copy of the Histopathology report, site of biopsy, and clinical history.
Conclusion
The IMMUNOHISTOCHEMISTRY MUC4 Test is a valuable diagnostic tool for identifying the presence and distribution of MUC4 protein in tissue samples. It can aid in the diagnosis and prognosis of certain diseases, providing valuable information for clinicians and pathologists.
| Test Name | IMMUNOHISTOCHEMISTRY MUC4 Test |
|---|---|
| Components | |
| Price | 520.0 AED |
| Sample Condition | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Report Delivery | 10 days |
| Method | Immunohistochemistry |
| Test type | Cancer |
| Doctor | Oncologist, Pathologist |
| Test Department: | HISTOLOGY |
| Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test Details | Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples using antibodies. MUC4 is a protein that is commonly expressed in various tissues, including the respiratory and digestive tracts. The MUC4 test involves the use of specific antibodies that bind to the MUC4 protein in tissue samples. These antibodies are usually labeled with a colored or fluorescent marker, which allows for visualization of the protein under a microscope. The MUC4 test is often used in diagnostic pathology to identify the presence and distribution of MUC4 protein in tissue samples. It can help in the diagnosis and classification of certain diseases, such as pancreatic cancer and lung adenocarcinoma. The procedure for performing the MUC4 test involves the following steps: 1. Tissue sample preparation: The tissue sample is collected from a patient and processed to create thin sections that can be mounted on glass slides. 2. Antigen retrieval: The tissue sections are treated to retrieve the MUC4 protein antigen, which may be masked or damaged during the tissue processing. 3. Blocking: The tissue sections are treated with a blocking solution to prevent non-specific binding of antibodies. 4. Primary antibody incubation: The tissue sections are incubated with the primary antibody specific to the MUC4 protein. This antibody binds to the MUC4 protein if it is present in the tissue sample. 5. Secondary antibody incubation: The tissue sections are then incubated with a secondary antibody that is labeled with a colored or fluorescent marker. This secondary antibody binds to the primary antibody, allowing for visualization of the MUC4 protein. 6. Visualization: The tissue sections are examined under a microscope to visualize the presence and distribution of the MUC4 protein. The colored or fluorescent marker indicates the location of the MUC4 protein in the tissue sample. The results of the MUC4 test can help in the diagnosis and prognosis of certain diseases. The presence or absence of MUC4 protein, as well as its distribution in the tissue sample, can provide valuable information for clinicians and pathologists. |
