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Immunohistochemistry Inhibin Test

Original price was: 460 د.إ.Current price is: 410 د.إ.

-11%

The Immunohistochemistry Inhibin Test is a specialized diagnostic procedure used to detect the presence of inhibin protein in tissue samples. Inhibin is a hormone that plays a crucial role in regulating the production of follicle-stimulating hormone (FSH) and has significant implications in reproductive biology, including ovarian and testicular function. This test is particularly useful in the diagnosis of various reproductive and endocrine disorders, as well as in identifying certain types of tumors that may produce inhibin, such as granulosa cell tumors in the ovary and Sertoli cell tumors in the testis.

Performed using immunohistochemistry (IHC) techniques, the test involves the application of antibodies specific to inhibin on tissue sections to visualize the hormone’s presence under a microscope. This method allows for precise localization and quantification of inhibin expression within the tissue architecture, providing valuable insights into the pathology of the specimen being examined.

At DNA Labs UAE, the Immunohistochemistry Inhibin Test is available for 410 AED. The lab is equipped with state-of-the-art facilities and employs advanced methodologies to ensure accurate and reliable test results. Patients and healthcare providers can expect professional service and timely delivery of results, making DNA Labs UAE a preferred choice for diagnostic and research purposes in the region.

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  • This test is not intended for medical diagnosis or treatment
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IMMUNOHISTOCHEMISTRY INHIBIN Test

Test Name: IMMUNOHISTOCHEMISTRY INHIBIN Test

Components: Inhibin

Price: 410.0 AED

Sample Condition: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Report Delivery: Sample Daily by 6 pm; Report Block: 5 days, Tissue Biopsy: 5 days, Tissue large complex: 7 days

Method: Immunohistochemistry

Test Type: Cancer

Doctor: Oncologist, Pathologist

Test Department: DNA Labs UAE

Pre Test Information: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.

Test Details

Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissues using antibodies that bind to the target protein. It is commonly used in research and diagnostic laboratories to study the distribution and expression of proteins in various tissues.

Inhibin is a protein hormone that is primarily produced by the ovaries and testes. It plays a role in regulating the production of follicle-stimulating hormone (FSH) in the pituitary gland. In women, inhibin is produced by the granulosa cells of ovarian follicles, while in men, it is produced by Sertoli cells in the testes.

The inhibin test using immunohistochemistry involves the following steps:

  1. Tissue sample preparation: A tissue sample is collected, typically through a biopsy or surgical procedure. The sample is then processed and embedded in paraffin or frozen for sectioning.
  2. Sectioning: The tissue sample is cut into thin sections, usually around 4-6 micrometers thick, using a microtome. These sections are then mounted onto glass slides.
  3. Antigen retrieval: If necessary, antigen retrieval may be performed to improve the accessibility of the target protein. This step involves treating the tissue sections with heat or enzymes to reverse the cross-linking and allow better antibody binding.
  4. Blocking: To prevent non-specific antibody binding, the tissue sections are treated with a blocking solution, such as serum or bovine serum albumin (BSA).
  5. Primary antibody incubation: The tissue sections are incubated with a primary antibody specific to inhibin. This antibody recognizes and binds to the target protein in the tissue.
  6. Secondary antibody incubation: After washing off any unbound primary antibody, the tissue sections are incubated with a secondary antibody conjugated to a detection system, such as a fluorescent dye or enzyme.
  7. Visualization: The bound secondary antibody is visualized using a microscope or other imaging systems. Fluorescent dyes emit light of a specific wavelength when excited by a specific light source, while enzyme-based detection systems produce a color change upon substrate addition.
  8. Counterstaining: To visualize the tissue structure and enhance contrast, the tissue sections may be counterstained with dyes like hematoxylin or eosin.

The result of an inhibin immunohistochemistry test can help determine the presence, distribution, and intensity of inhibin expression in the tissue sample. It can be used to study various diseases and conditions related to inhibin, such as ovarian tumors, testicular tumors, and disorders of reproductive function.

Test Name IMMUNOHISTOCHEMISTRY INHIBIN Test
Components
Price 410.0 AED
Sample Condition Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Report Delivery Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days
Method Immunohistochemistry
Test type Cancer
Doctor Oncologist, Pathologist
Test Department:
Pre Test Information Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Test Details

Immunohistochemistry (IHC) is a technique used to detect specific proteins in tissues using antibodies that bind to the target protein. It is commonly used in research and diagnostic laboratories to study the distribution and expression of proteins in various tissues.

Inhibin is a protein hormone that is primarily produced by the ovaries and testes. It plays a role in regulating the production of follicle-stimulating hormone (FSH) in the pituitary gland. In women, inhibin is produced by the granulosa cells of ovarian follicles, while in men, it is produced by Sertoli cells in the testes.

The inhibin test using immunohistochemistry involves the following steps:

1. Tissue sample preparation: A tissue sample is collected, typically through a biopsy or surgical procedure. The sample is then processed and embedded in paraffin or frozen for sectioning.

2. Sectioning: The tissue sample is cut into thin sections, usually around 4-6 micrometers thick, using a microtome. These sections are then mounted onto glass slides.

3. Antigen retrieval: If necessary, antigen retrieval may be performed to improve the accessibility of the target protein. This step involves treating the tissue sections with heat or enzymes to reverse the cross-linking and allow better antibody binding.

4. Blocking: To prevent non-specific antibody binding, the tissue sections are treated with a blocking solution, such as serum or bovine serum albumin (BSA).

5. Primary antibody incubation: The tissue sections are incubated with a primary antibody specific to inhibin. This antibody recognizes and binds to the target protein in the tissue.

6. Secondary antibody incubation: After washing off any unbound primary antibody, the tissue sections are incubated with a secondary antibody conjugated to a detection system, such as a fluorescent dye or enzyme.

7. Visualization: The bound secondary antibody is visualized using a microscope or other imaging systems. Fluorescent dyes emit light of a specific wavelength when excited by a specific light source, while enzyme-based detection systems produce a color change upon substrate addition.

8. Counterstaining: To visualize the tissue structure and enhance contrast, the tissue sections may be counterstained with dyes like hematoxylin or eosin.

The result of an inhibin immunohistochemistry test can help determine the presence, distribution, and intensity of inhibin expression in the tissue sample. It can be used to study various diseases and conditions related to inhibin, such as ovarian tumors, testicular tumors, and disorders of reproductive function.