IMMUNOHISTOCHEMISTRY CD117 Test
At DNA Labs UAE, we offer the IMMUNOHISTOCHEMISTRY CD117 Test at a cost of AED 410.0.
Test Components
- Price: 410.0 AED
Sample Condition
To perform the test, please submit tumor tissue in 10% Formal-saline or a Formalin fixed paraffin embedded block. The sample should be shipped at room temperature. Additionally, provide a copy of the Histopathology report, site of biopsy, and clinical history.
Report Delivery
The sample is processed daily, and the report will be delivered by 6 pm. The turnaround time for the report is as follows:
- Sample Block: 5 days
- Tissue Biopsy: 5 days
- Tissue large complex: 7 days
Method
The IMMUNOHISTOCHEMISTRY CD117 Test is performed using immunohistochemistry. This test is primarily used for cancer diagnosis.
Doctor
The test is conducted by our team of experienced oncologists and pathologists.
Test Department
The IMMUNOHISTOCHEMISTRY CD117 Test is conducted in our specialized Test Department.
Pre Test Information
Before conducting the test, please provide a copy of the Histopathology report, site of biopsy, and clinical history.
Test Details
The IMMUNOHISTOCHEMISTRY CD117 Test is a diagnostic test used to detect the presence of CD117, also known as c-Kit, in tissue samples. CD117 is a protein found on the surface of certain cells, including hematopoietic stem cells and mast cells. It plays a crucial role in cell growth and differentiation.
The CD117 test is commonly used in the diagnosis and classification of various cancers, particularly gastrointestinal stromal tumors (GISTs). GISTs are tumors that arise from the cells of the gastrointestinal tract and are characterized by the presence of a mutation in the c-Kit gene.
The CD117 test helps identify the presence of CD117/c-Kit protein on the tumor cells, confirming the diagnosis of GIST. The test is performed on tissue samples obtained through a biopsy or surgical resection. The tissue sample is processed, embedded in paraffin, and cut into thin sections. These sections are then mounted onto glass slides and subjected to a series of staining procedures using specific antibodies against CD117.
The antibodies bind to the CD117 protein, and the resulting staining pattern can be visualized under a microscope. A positive CD117 test indicates the presence of CD117 protein on the tumor cells, suggesting a diagnosis of GIST or other CD117-positive cancers. This information is crucial for determining the appropriate treatment options, as some targeted therapies specifically target the CD117 protein.
It is important to note that the CD117 test is just one component of a comprehensive diagnostic workup and should be interpreted in conjunction with other clinical and pathological findings. A pathologist with expertise in immunohistochemistry will evaluate the stained slides and provide a report on the results of the CD117 test.
| Test Name | IMMUNOHISTOCHEMISTRY CD117 Test |
|---|---|
| Components | |
| Price | 410.0 AED |
| Sample Condition | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Report Delivery | Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days |
| Method | Immunohistochemistry |
| Test type | Cancer |
| Doctor | Oncologist, Pathologist |
| Test Department: | |
| Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test Details | The immunohistochemistry CD117 test is a diagnostic test used to detect the presence of CD117, also known as c-Kit, in tissue samples. CD117 is a protein that is found on the surface of certain cells, including hematopoietic stem cells and mast cells. It plays a crucial role in cell growth and differentiation. The CD117 test is commonly used in the diagnosis and classification of various cancers, particularly gastrointestinal stromal tumors (GISTs). GISTs are tumors that arise from the cells of the gastrointestinal tract and are characterized by the presence of a mutation in the c-Kit gene. The CD117 test helps to identify the presence of CD117/c-Kit protein on the tumor cells, confirming the diagnosis of GIST. The test is performed on tissue samples obtained through a biopsy or surgical resection. The tissue sample is processed, embedded in paraffin, and cut into thin sections. These sections are then mounted onto glass slides and subjected to a series of staining procedures using specific antibodies against CD117. The antibodies bind to the CD117 protein, and the resulting staining pattern can be visualized under a microscope. A positive CD117 test indicates the presence of CD117 protein on the tumor cells, suggesting a diagnosis of GIST or other CD117-positive cancers. This information is crucial for determining the appropriate treatment options, as some targeted therapies specifically target the CD117 protein. It is important to note that the CD117 test is just one component of a comprehensive diagnostic workup, and it should be interpreted in conjunction with other clinical and pathological findings. A pathologist with expertise in immunohistochemistry will evaluate the stained slides and provide a report on the results of the CD117 test. |
