IMMUNOHISTOCHEMISTRY ALK-1 Test
Test Name: IMMUNOHISTOCHEMISTRY ALK-1 Test
Components: ALK-1 antibody
Price: 420.0 AED
Sample Condition: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Report Delivery: 10 days
Method: Immunohistochemistry
Test Type: Cancer
Doctor: Oncologist, Pathologist
Test Department: DNA Labs UAE
Pre Test Information: Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
What is the IMMUNOHISTOCHEMISTRY ALK-1 Test?
The ALK-1 (Anaplastic Lymphoma Kinase-1) test is an immunohistochemistry (IHC) test used to detect the presence of ALK protein in tissue samples. ALK is a receptor tyrosine kinase that is normally expressed in the nervous system, but can also be aberrantly expressed in certain types of cancer, such as anaplastic large cell lymphoma (ALCL) and non-small cell lung cancer (NSCLC).
The ALK-1 test involves staining tissue sections with an antibody that specifically binds to the ALK protein. If ALK is present in the tissue, the antibody will bind to it, and this can be visualized under a microscope using a detection system. The presence of ALK protein in the tissue indicates that the cancer cells may be driven by ALK gene rearrangements, which can be targeted with specific ALK inhibitors.
Diagnosis and Classification of ALCL and NSCLC
The ALK-1 test is commonly used in the diagnosis and classification of ALCL and NSCLC. It helps identify patients who may benefit from targeted therapies that inhibit the ALK pathway. Additionally, the ALK-1 test can be used to monitor treatment response and disease progression in patients undergoing ALK inhibitor therapy.
Role in Cancer Management
Overall, the ALK-1 immunohistochemistry test plays a crucial role in the management of ALK-positive cancers by providing valuable information for diagnosis, treatment selection, and monitoring.
| Test Name | IMMUNOHISTOCHEMISTRY ALK-1 Test |
|---|---|
| Components | |
| Price | 420.0 AED |
| Sample Condition | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Report Delivery | 10 days |
| Method | Immunohistochemistry |
| Test type | Cancer |
| Doctor | Oncologist, Pathologist |
| Test Department: | |
| Pre Test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test Details |
The ALK-1 (Anaplastic Lymphoma Kinase-1) test is an immunohistochemistry (IHC) test used to detect the presence of ALK protein in tissue samples. ALK is a receptor tyrosine kinase that is normally expressed in the nervous system, but can also be aberrantly expressed in certain types of cancer, such as anaplastic large cell lymphoma (ALCL) and non-small cell lung cancer (NSCLC). The ALK-1 test involves staining tissue sections with an antibody that specifically binds to the ALK protein. If ALK is present in the tissue, the antibody will bind to it, and this can be visualized under a microscope using a detection system. The presence of ALK protein in the tissue indicates that the cancer cells may be driven by ALK gene rearrangements, which can be targeted with specific ALK inhibitors. The ALK-1 test is commonly used in the diagnosis and classification of ALCL and NSCLC. It helps identify patients who may benefit from targeted therapies that inhibit the ALK pathway. Additionally, the ALK-1 test can be used to monitor treatment response and disease progression in patients undergoing ALK inhibitor therapy. Overall, the ALK-1 immunohistochemistry test plays a crucial role in the management of ALK-positive cancers by providing valuable information for diagnosis, treatment selection, and monitoring. |
